Organic & Biomolecular Chemistry

The first issue of Organic & Biomolecular Chemistry, formed from the merger and strategic development of Perkin Transactions 1 & 2, will be published on 10 January 2003. The electronic version will go up on 23 December 2002.

Barbara Imperiali, Francois Diederich, Ben Feringa and Chi-Huey Wong are amongst the first eminent scientists to publish Advance Articles in the journal. Further details are given below. The first issue will also feature contributions from Steve Ley, Jay Siegel and Michael Burkart, these will be available online soon.

Advance Articles Now Available on the Journal Website Include:-


    HIV-1 Protease: Mechanism and Drug Discovery
    Chi-Huey Wong, Scripps, USA

    A donor-acceptor substituted molecular motor: unidirectional rotation driven by visible light.
    Ben Feringa, Groningen, The Netherlands

    A new synthesis of porphobilinogen analogues, inhibitors of hydroxymethylbilane synthase
    Finian Leeper, Cambridge, UK

    Non-steady-state kinetic study of the SN2 reaction between p-nitrophenoxide ion and methyl iodide in aprotic solvents containing water. Evidence for a 2-step mechanism.
    Vernon D. Parker, Utah State, USA

    Facilitated transport of sodium or potassium chloride across vesicle membranes using a ditopic salt-binding macrobicycle
    Bradley D. Smith, Notre Dame, USA

    From central to planar chirality, the first example of atropenantioselective cycloetherification
    Jieping Zhu, CNRS, France

    Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity
    Franois Diederich, ETH, Switzerland

    Peptides to peptidomimetics: Towards the design and synthesis of bioavailable inhibitors of oligosaccharyl transferas

Contact: Christopher Marshall
Royal Society of Chemistry

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