Barbara Imperiali, Francois Diederich, Ben Feringa and Chi-Huey Wong are amongst the first eminent scientists to publish Advance Articles in the journal. Further details are given below. The first issue will also feature contributions from Steve Ley, Jay Siegel and Michael Burkart, these will be available online soon.

Advance Articles Now Available on the Journal Website Include:-

Perspective

HIV-1 Protease: Mechanism and Drug Discovery
Chi-Huey Wong, Scripps, USA

A donor-acceptor substituted molecular motor: unidirectional rotation driven by visible light.
Ben Feringa, Groningen, The Netherlands

A new synthesis of porphobilinogen analogues, inhibitors of hydroxymethylbilane synthase
Finian Leeper, Cambridge, UK

Non-steady-state kinetic study of the SN2 reaction between p-nitrophenoxide ion and methyl iodide in aprotic solvents containing water. Evidence for a 2-step mechanism.
Vernon D. Parker, Utah State, USA

Facilitated transport of sodium or potassium chloride across vesicle membranes using a ditopic salt-binding macrobicycle
Bradley D. Smith, Notre Dame, USA

From central to planar chirality, the first example of atropenantioselective cycloetherification
Jieping Zhu, CNRS, France

Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity
Franois Diederich, ETH, Switzerland

Peptides to peptidomimetics: Towards the design and synthesis of bioavailable inhibitors of oligosaccharyl transferas
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