HOME >> BIOLOGY >> NEWS
Other highlights in the August 4 JNCI

Low Levels of "Good" Cholesterol Associated With Increased Postmenopausal Breast Cancer Risk

Low levels of high-density lipoprotein (HDL) cholesterol--the "good" cholesterol--are associated with an increased risk of postmenopausal breast cancer in overweight and obese women, according to a new study.

Low HDL cholesterol is a component of metabolic syndrome, which is also characterized by obesity, glucose intolerance, and hypertension. Both metabolic syndrome and breast cancer have been increasing worldwide. Increased levels of insulin and insulin-like growth factor in metabolic syndrome have been linked to breast cancer, but the role of other biomarkers, such as HDL cholesterol is not known.

Anne-Sofie Furberg, M.D., Ph.D., of the University of Troms in Norway, and colleagues analyzed data from a Norwegian cohort of nearly 39,000 women over a follow-up period of 21 years. Low levels of HDL cholesterol were associated with an increased risk of postmenopausal breast cancer in women who were overweight or obese. The association was strongest in women who gained weight over the years of follow-up.

Contacts:

  • Anne-Sofie Furberg, Institute of Community Medicine, University of Troms, 47-99-41-4007, anne-sofie.furberg@ism.uit.no
  • Inger Thune, Institute of Community Medicine, 47 91 37 27 17, inger.thune@ism.uit.no

    HER-2/neu Overexpression in Breast Cancer Does Not Adversely Influence Response to First-Line Chemotherapy

    Breast cancer patients with tumors that overexpress the gene HER-2/neu are more likely to have a poor clinical outcome. A new study finds that HER-2/neu overexpression does not lead to a poorer response to chemotherapy in women with metastatic breast cancer.

    There is some evidence that HER-2/neu overexpression is associated with a better response to anthracycline-based chemotherapy, b
    '"/>



  • Contact: Sarah L. Zielinski
    jncimedia@oupjournals.org
    301-841-1287
    Journal of the National Cancer Institute
    3-Aug-2004


    Page: 1 2 3

    Related biology news :

    1. Other highlights in the September 1 JNCI
    2. Other highlights in the August 18 JNCI
    3. Other highlights in the July 7 JNCI
    4. Other highlights in the June 16 JNCI
    5. Other Highlights in the June 2 JNCI
    6. Other highlights in the May 19 JNCI
    7. Other highlights in the May 5 JNCI
    8. Other highlights of the March 17 issue of JNCI
    9. Other highlights in the March 3 issue of JNCI
    10. Other highlights in the February 18 issue of JNCI
    11. Other highlights in the February 4 issue of JNCI

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:11/19/2019)... ... November 19, 2019 , ... Diagenode, ... and Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader in life ... will offer Single-Cell ATAC-Seq (scATAC-Seq) Services, featuring Bio-Rad’s Droplet Digital PCR technology, to ...
    (Date:11/14/2019)... ... ... Personalized Stem Cells, Inc (“PSC”), a human adipose-derived stem cell company, ... stem cell treatment of knee osteoarthritis . The first treatment came shortly after the ... , In July of 2019, PSC received FDA approval for a New ...
    (Date:11/12/2019)... IRVINE, Calif. (PRWEB) , ... November 12, 2019 ... ... an open call for proposals from nonprofit U.S. universities and research institutions for ... grant will provide support of up to $1.2 million per site for the ...
    Breaking Biology News(10 mins):
    (Date:11/5/2019)... ... November 05, 2019 , ... Focal Healthcare ... Mark for its Fusion Bx 2.0 prostate fusion biopsy solution. By combining information ... Bx 2.0 will give urologists across Europe the ability to perform targeted transrectal ...
    (Date:11/2/2019)... , ... October 31, 2019 , ... ... Adaptive Biotechnologies in a live webinar on Friday, November 15, ... immuno-oncology. , Immunosequencing, the science of profiling T-cell receptors (TCRs) and B-cell ...
    (Date:10/30/2019)... , ... October 30, 2019 , ... ... to showcase the many roles innovation and technology play in educating the next ... Innovation, featured hands-on learning opportunities and presentations by WesternU administrators and representatives of ...
    (Date:10/29/2019)... Mass. (PRWEB) , ... October 29, 2019 , ... ... spectral signature of the skin*. Using Silios CMS-C multispectral imagers , researchers ... new approach can replace identification based on retinal imaging, face recognition, fingerprints and ...
    Breaking Biology Technology:
    Cached News: