HOME >> BIOLOGY >> NEWS
Other highlights in the January 21 issue of JNCI

Review Examines Effect of Genetic Counseling on Awareness, Risk Perception
Genetic counseling leads to increased knowledge of cancer genetics and does not have an adverse impact on anxiety or distress of the patients being counseled, according to a systematic review.

The identification of genes that are associated with a high risk of certain types of cancer has led to an increased demand for genetic counseling from individuals at increased risk for the disease. To determine the quality and strength of evidence related to psychological outcomes of genetic counseling for familial cancer, Dejana Braithwaite, of the Institute of Public Health at the University of Cambridge, and colleagues conducted a meta-analysis of 21 controlled trials and prospective studies of the impact of genetic counseling for breast, ovarian, and colorectal cancer on cognitive, affective, and behavioral outcomes.

They found that, in controlled studies, genetic counseling for familial cancer was associated with improved knowledge of cancer genetics but did not alter the level of perceived risk, whereas, in prospective studies, there was an improvement in accuracy of perceived risk. The authors conclude that these findings should be investigated further through well-designed, well-reported, randomized controlled trials with suitable comparison groups and additional outcome measures.

Gene Mutation Affects Sensitivity of Cancer Cells to Chemotherapy Drugs
A research team has found that a specific mutation in a gene critical to folate metabolism alters the sensitivity of colon and breast cancer cells to common chemotherapy drugs, suggesting that the gene might be a useful marker for tailoring chemotherapy or that it is a potential target to improve sensitivity to chemotherapy.

Folate is a form of a B vitamin that is critical for DNA synthesis, DNA repair, and epigenetic regulation. About 35% of the general North American population h
'"/>

Contact: Katherine Arnold
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
20-Jan-2004


Page: 1 2 3

Related biology news :

1. Other highlights in the September 1 JNCI
2. Other highlights in the August 18 JNCI
3. Other highlights in the August 4 JNCI
4. Other highlights in the July 7 JNCI
5. Other highlights in the June 16 JNCI
6. Other Highlights in the June 2 JNCI
7. Other highlights in the May 19 JNCI
8. Other highlights in the May 5 JNCI
9. Other highlights of the March 17 issue of JNCI
10. Other highlights in the March 3 issue of JNCI
11. Other highlights in the February 18 issue of JNCI

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/17/2016)... 17, 2016 ABI Research, the leader ... global biometrics market will reach more than $30 ... from 2015. Consumer electronics, particularly smartphones, continue to ... anticipated to reach two billion shipments by 2021 ... Pavlakis , Research Analyst at ABI Research. "Surveillance ...
(Date:3/14/2016)... , March 14, 2016 NXTD ) ... mobile commerce market, announces the airing of a new series ... the week of March 21 st .  The commercials will ... its popular Squawk on the Street show. --> ... the growing mobile commerce market, announces the airing of a ...
(Date:3/11/2016)... --> --> ... Recognition Market by Technology (Pattern Recognition), by Component (Hardware, ... Type (On-Premises and Cloud), by Industry Vertical and by ... the global market is expected to grow from USD ... 2020, at a CAGR of 19.1%. , ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... ... 05, 2016 , ... CereScan, the nation’s leader in providing ... National Stroke Awareness Month in May. An infographic created by CereScan will ... CereScan will donate $1 up to a maximum of $3,000 through users who ...
(Date:5/4/2016)... NY (PRWEB) , ... May 04, 2016 , ... The ... a genetic disorder that causes tumors to grow on nerves throughout the body. It ... cure. , Through numerous community events held during the month of May, as well ...
(Date:5/3/2016)... PUNE, India , May 3, 2016 ... Type (DNA Chip (Genomics, Drug Discovery, Gene ... Chips), End user (Academics Institutes, Diagnostics Centers), ... 2020" published by MarketsandMarkets, the market is ... 2020 from USD 7.63 Billion in 2015, ...
(Date:5/3/2016)... ... May 03, 2016 , ... Flagship Biosciences, the ... Gillett to its Board of Directors. Dr. Gillett recently retired from Charles River ... President and Chief Scientific Officer. A board-certified veterinary pathologist, Dr. Gillett joined Charles ...
Breaking Biology Technology:
Cached News: