HOME >> BIOLOGY >> NEWS
Oxidants play major role in healing of damaged blood vessels

Researchers and clinicians have long labeled oxidants as villains in the fight against heart disease. But clinical trials using anti-oxidants against heart disease have been disappointing.

New research here is showing these same oxidants are critical for the healing of damage to the cardiovascular system and may tell us why anti-oxidants haven't worked.

Without the right mix of oxidants - also called "free radicals" -- at the sites of vascular injury, blood vessel walls won't heal. This finding offers one explanation for why antioxidant therapies haven't been effective in treating heart disease, as had once been hoped.

In a paper published in a recent issue of the journal Circulation Research, scientists at Ohio State University reported that endothelial cells adjacent to wounds on the inner surface of the vessel wall produced more oxidants than did identical cells farther away from the wound.

"We were looking at the possibility that when you stress endothelial cells, oxidants would be produced by these cells, damaging them," explained Pascal Goldschmidt, director of Ohio State University's Heart and Lung Institute. "Instead, we found that the oxidants are an important part of the repair process."

The report, led by Leni Moldovan, a postdoctoral fellow in Goldschmidt's laboratory, focussed on the endothelium, the layer of smooth cells that lines the walls of every blood vessel in the
'"/>

Contact: Pascal Goldschmidt
goldschmidt-1@medctr.osu.edu
614-688-5779
Ohio State University
11-Apr-2000


Page: 1 2 3 4

Related biology news :

1. Brown ecologist garners major National Science Foundation grant
2. Genetic mutation found that is major contributor to type 1 diabetes
3. Researchers report major advance in gene therapy technique
4. K-State business researchers to help with major study on food supply veterinary medicine
5. NPS Pharma and VIMAC Ventures locate at MaRS, a major new research and enterprise center in Toronto
6. Kinase backgrounder: Iressa discovery part of major kinase project at Dana-Farber
7. Inflammation, hypertension are focus of major new MCG research program
8. Gene plays major role in formation of stem cells and cancer
9. Researchers make major gain in understanding how prions jump species
10. Scientists crack genome sequence of a major parasitic pathogen
11. Diet a major factor in breast cancer time for government action

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2017)... YORK , April 4, 2017   EyeLock ... today announced that the United States Patent and Trademark ... patent broadly covers the linking of an iris image ... same transaction) and represents the company,s 45 th ... latest patent is very timely given the multi-modal biometric ...
(Date:3/30/2017)... 30, 2017  On April 6-7, 2017, Sequencing.com will ... hackathon at Microsoft,s headquarters in ... focus on developing health and wellness apps that provide ... the Genome is the first hackathon for personal ... largest companies in the genomics, tech and health industries ...
(Date:3/30/2017)... 2017 Trends, opportunities and forecast in this ... technology (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, ... end use industry (government and law enforcement, commercial and ... and others), and by region ( North America ... Asia Pacific , and the Rest of the ...
Breaking Biology News(10 mins):
(Date:9/20/2017)... Station, TX (PRWEB) , ... ... ... Services, LLC (IPS), a leading global provider of engineering, architecture, project controls, ... provider of prefabricated cleanrooms, today announced the unveiling of the iCON™ brand ...
(Date:9/20/2017)... ... September 20, 2017 , ... RoviSys, a leading independent provider ... opening of an office in Taipei, Taiwan. This new location allows RoviSys to ... new relationships in the region. Located in the Neihu area of Taipei, the ...
(Date:9/19/2017)... ... September 19, 2017 , ... The new and improved Oakton® pocket testers, ... even stand upright with a new cap design that is versatile, functional and leakproof. ... who need to test water quality. , The Oakton pocket testers have many user-friendly ...
(Date:9/19/2017)... (PRWEB) , ... September 19, ... ... York State Department of Financial Services (NYS DFS) cybersecurity regulations have ... banking, finance and insurance organizations operating in the state (“Covered Entities”) to ...
Breaking Biology Technology:
Cached News: