HOME >> BIOLOGY >> NEWS
PCB exposure is bad news for the female sex drive

Female rats that are exposed to PCBs in the womb are reluctant to mate as adults. This raises the possibility that similar chemical contaminants can cause low sex drives in women.

PCBs are a group of stable chemical additives once widely used in the production of pesticides, lubricants and plastics. Their use was banned in many countries after it became clear that some PCBs mimic hormones. But there is strong evidence that PCBs are still widespread in the environment. The food crisis that struck Belgium in June was partly caused by PCB contamination of poultry and dairy produce.

Zoologists Yu-Wen Chung and Lynwood Clemens of Michigan State University in East Lansing tested the effects on rats of two commercial PCBs, Aroclor 1221 and 1254. A1221 is known to mimic oestrogen and A1254 is thought to reduce dopamine levels in the brain.

They injected 40 pregnant rats with either pure sesame oil or a mixture of oil and the PCBs, first on day 14 of gestation, then on the day of the pup's birth and again 10 days later while the pups were suckling. Two months later, Chung and Clemens looked at the sexual behaviour of the female offspring.

"Female rats normally adopt a stereotypical posture when copulating, raising their back and hindquarters to help the male mate," says Chung. But rats exposed to A1221 did not indulge in this sexual come-on nearly as often as rats exposed to A1254 or those that had not been exposed to either PCB.

A second test paired female and large male rats in a cage with two compartments. If the females didn't feel like mating, they could escape into the second chamber through a hole too small for the larger frustrated males to follow.

It turned out that females exposed to A1221 left the males more often and took longer to return after each copulation attempt by the males (Bulletin of Environmental Contamination and Toxicology, vol 62, p 664). "We found that females stayed away
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-171-331-2751
New Scientist
4-Aug-1999


Page: 1 2

Related biology news :

1. USC study links historical increases in life span to lower childhood exposure to infection
2. 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
3. Managing occupational exposures to potential bioterrorist agents
4. Infant rats eagerly accept high concentrations of alcohol upon first exposure
5. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
6. Transplant rejection averted by simple light exposure in Stanford animal study
7. OHSU researchers discover possible connection between infant hormone exposure, obesity
8. Prenatal exposure to second-handsmoke greater for disadvantaged children, study finds
9. Deficits associated with prenatal alcohol exposure can be seen as early as infancy
10. Household activities release a cloud of dust, increasing exposure to particulate pollution
11. Models help estimate childrens exposure to toxins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: PCB exposure bad news for the female sex drive

(Date:2/5/2015)... , Jan. 26, 2015 NXT-ID, Inc. (NASDAQ: ... "Company"), a biometric authentication company focused on the growing ... corporate website ( http://www.nxt-id.com/ ) as part of its ... wallet. The Company launched its new consumer website for ... Pereira , CEO of NXT-ID said, "Our new corporate ...
(Date:2/5/2015)...  It is gratifying to see that the Obama ... science as a means to better understand human biology, ... was honored to participate in today,s White House event ... Since the 1980s my teams have been ... sequenced genome of a free living organism, the first ...
(Date:1/22/2015)... Jan. 13, 2015  Today, FreeWavz ( www.FreeWavz.com ), ... crowdfunding campaign on Fundable, https://www.fundable.com/freewavz . FreeWavz ... production capacity to meet customer demand. ... http://photos.prnewswire.com/prnh/20150113/168790 Invented by ...
Breaking Biology News(10 mins):NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2
(Date:2/26/2015)... Los Angeles, CA (PRWEB) February 26, 2015 ... organizing an online demonstration to support life extension technologies ... to 8pm UTC, Universal Coordinated Time, on March 21st ... around the world. , Eric Schulke, Founder of ... we must act with urgency. The Movement for Indefinite ...
(Date:2/26/2015)... BioEnterprise today announced that Northeast Ohio ... in growth funding during the past 13 years.  Funding ... – including the Ohio Third Frontier - and federal ... raised in the past five years. ... BioEnterprise Midwest Healthcare Growth Capital  Report.   ...
(Date:2/26/2015)... February 26, 2015 RURO, Inc., a ... FreezerPro® version 6.2 – the latest update to the ... is that of a quick and easy method to ... the latest version, RURO engineering has enhanced the system’s ... move large amounts of sample records. , "FreezerPro ...
(Date:2/26/2015)... Calif. , Feb. 26, 2015 ... Gold Partner status in Oracle PartnerNetwork. In attaining Gold ... its commitment to establish Oracle-related knowledge in delivering Ceres, ... challenges of joint customers. Originally developed for ... to rapidly zoom in and out of massive amounts ...
Breaking Biology Technology:Indefinite Life Extension Activists Organize Online Demonstration 2Indefinite Life Extension Activists Organize Online Demonstration 3More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 2More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 3More Than $2 Billion Invested in Northeast Ohio Bioscience Start-Up Companies Since 2002 4RURO Releases FreezerPro® version 6.2 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4
Cached News: