HOME >> BIOLOGY >> NEWS
PCB exposure is bad news for the female sex drive

Female rats that are exposed to PCBs in the womb are reluctant to mate as adults. This raises the possibility that similar chemical contaminants can cause low sex drives in women.

PCBs are a group of stable chemical additives once widely used in the production of pesticides, lubricants and plastics. Their use was banned in many countries after it became clear that some PCBs mimic hormones. But there is strong evidence that PCBs are still widespread in the environment. The food crisis that struck Belgium in June was partly caused by PCB contamination of poultry and dairy produce.

Zoologists Yu-Wen Chung and Lynwood Clemens of Michigan State University in East Lansing tested the effects on rats of two commercial PCBs, Aroclor 1221 and 1254. A1221 is known to mimic oestrogen and A1254 is thought to reduce dopamine levels in the brain.

They injected 40 pregnant rats with either pure sesame oil or a mixture of oil and the PCBs, first on day 14 of gestation, then on the day of the pup's birth and again 10 days later while the pups were suckling. Two months later, Chung and Clemens looked at the sexual behaviour of the female offspring.

"Female rats normally adopt a stereotypical posture when copulating, raising their back and hindquarters to help the male mate," says Chung. But rats exposed to A1221 did not indulge in this sexual come-on nearly as often as rats exposed to A1254 or those that had not been exposed to either PCB.

A second test paired female and large male rats in a cage with two compartments. If the females didn't feel like mating, they could escape into the second chamber through a hole too small for the larger frustrated males to follow.

It turned out that females exposed to A1221 left the males more often and took longer to return after each copulation attempt by the males (Bulletin of Environmental Contamination and Toxicology, vol 62, p 664). "We found that females stayed away
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-171-331-2751
New Scientist
4-Aug-1999


Page: 1 2

Related biology news :

1. USC study links historical increases in life span to lower childhood exposure to infection
2. 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
3. Managing occupational exposures to potential bioterrorist agents
4. Infant rats eagerly accept high concentrations of alcohol upon first exposure
5. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
6. Transplant rejection averted by simple light exposure in Stanford animal study
7. OHSU researchers discover possible connection between infant hormone exposure, obesity
8. Prenatal exposure to second-handsmoke greater for disadvantaged children, study finds
9. Deficits associated with prenatal alcohol exposure can be seen as early as infancy
10. Household activities release a cloud of dust, increasing exposure to particulate pollution
11. Models help estimate childrens exposure to toxins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: PCB exposure bad news for the female sex drive

(Date:10/19/2014)... in India over the last 30 years contributed ... growth during that time, according to a new ... Change ., "Energy access is fundamental to development: ... including education, communication, and health," says IIASA researcher ... increased energy access is widely agreed to be ...
(Date:10/17/2014)... – Accurate knowledge regarding Ebola is critical and pertinent ... of hazardous global outbreak and epidemic. The Journal, ... a special issue, Ebola Virus and Public Health, to ... knowledge in this critical societal moment. , On ... Ebola for Clinicians . The primer was prepared by ...
(Date:10/16/2014)... war on the human body. Battles are won, ... pancreatic cancer, this stalemate—known as tumor dormancy—can last ... a phenomena that is poorly understood. , ... of Salvatore Torquato, a Professor of Chemistry at ... tumor dormancy and the switch to a malignant ...
Breaking Biology News(10 mins):Improved electricity access has little impact on climate change 2Modeling tumor dormancy 2
(Date:10/22/2014)... According to new market research report "Cloud Professional ... & Support), by Service Model (SaaS, PaaS, IaaS), ... & Community)) - Global Forecast to 2019", published ... Services Market into various sub-segments with an in-depth ... the drivers and restraints for this market with ...
(Date:10/22/2014)... HONG KONG , Oct. 22, 2014  aTyr ... today that rare disease expert John C. McKew ... Dr. McKew brings more than two decades of expertise ... National Institutes of Health, Wyeth Research and Genetics Institute, ... lead aTyr,s efforts to expand and translate its novel ...
(Date:10/20/2014)... ON , Oct. 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: ... $1.7 million which brings Q3 orders to $5.8 million and provides ... control projects in North America and one ... continue to bid new projects at record levels," said Peter ... were higher at the end of Q3 than they have been ...
(Date:10/20/2014)... Earle Martin , Chief ... that Ellen Teplitzky, an experienced attorney specializing in ... industry, has joined the firm as Director of ... practice. NDA Partners provides legal services, including ... to top law firms and their clients in ...
Breaking Biology Technology:Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
Cached News: