HOME >> BIOLOGY >> NEWS
PCB exposure is bad news for the female sex drive

Female rats that are exposed to PCBs in the womb are reluctant to mate as adults. This raises the possibility that similar chemical contaminants can cause low sex drives in women.

PCBs are a group of stable chemical additives once widely used in the production of pesticides, lubricants and plastics. Their use was banned in many countries after it became clear that some PCBs mimic hormones. But there is strong evidence that PCBs are still widespread in the environment. The food crisis that struck Belgium in June was partly caused by PCB contamination of poultry and dairy produce.

Zoologists Yu-Wen Chung and Lynwood Clemens of Michigan State University in East Lansing tested the effects on rats of two commercial PCBs, Aroclor 1221 and 1254. A1221 is known to mimic oestrogen and A1254 is thought to reduce dopamine levels in the brain.

They injected 40 pregnant rats with either pure sesame oil or a mixture of oil and the PCBs, first on day 14 of gestation, then on the day of the pup's birth and again 10 days later while the pups were suckling. Two months later, Chung and Clemens looked at the sexual behaviour of the female offspring.

"Female rats normally adopt a stereotypical posture when copulating, raising their back and hindquarters to help the male mate," says Chung. But rats exposed to A1221 did not indulge in this sexual come-on nearly as often as rats exposed to A1254 or those that had not been exposed to either PCB.

A second test paired female and large male rats in a cage with two compartments. If the females didn't feel like mating, they could escape into the second chamber through a hole too small for the larger frustrated males to follow.

It turned out that females exposed to A1221 left the males more often and took longer to return after each copulation attempt by the males (Bulletin of Environmental Contamination and Toxicology, vol 62, p 664). "We found that females stayed away
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-171-331-2751
New Scientist
4-Aug-1999


Page: 1 2

Related biology news :

1. USC study links historical increases in life span to lower childhood exposure to infection
2. 9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites
3. Managing occupational exposures to potential bioterrorist agents
4. Infant rats eagerly accept high concentrations of alcohol upon first exposure
5. Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
6. Transplant rejection averted by simple light exposure in Stanford animal study
7. OHSU researchers discover possible connection between infant hormone exposure, obesity
8. Prenatal exposure to second-handsmoke greater for disadvantaged children, study finds
9. Deficits associated with prenatal alcohol exposure can be seen as early as infancy
10. Household activities release a cloud of dust, increasing exposure to particulate pollution
11. Models help estimate childrens exposure to toxins

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: PCB exposure bad news for the female sex drive

(Date:4/17/2014)... trials to treat tuberculosis could be the basis for ... bacteria, fungal infections and parasites, yet evade resistance, according ... collaborators. , Led by U. of I. chemistry professor ... drug SQ109 attacks the tuberculosis bacterium, how the drug ... to malaria and how targeting multiple pathways reduces ...
(Date:4/17/2014)... word for chili peppers. Information about archaeological remains of ... of the appearance of words for chili peppers in ... domesticated and highlight the value of multi-proxy data analysis. ... of nine papers presented in a special feature issue ... Sciences on plant and animal domestication edited by ...
(Date:4/17/2014)... West Orange, NJ. April 16, 2014. Kessler Foundation ... for $1.8 million from the Department of Defense ... PhD, is principal investigator for the randomized, double-blinded, ... to improve bone and muscle strength after spinal ... Human Performance & Engineering Research at Kessler Foundation. ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2Chickens to chili peppers 2Chickens to chili peppers 3Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2
(Date:1/15/2014)... , Jan. 15, 2014 TaiGen Biotechnology Company, ... exclusive agreement with R-Pharm, a leading Russian pharmaceutical company, ... the Russian Federation , ... Independent States (CIS). Nemonoxacin is a novel antibiotic for the ...
(Date:1/14/2014)... 2014 Histogen, Inc., a regenerative medicine ... grown under simulated embryonic conditions, today announced that they ... Medical, Inc. for physician-dispensed aesthetic products containing Histogen’s proprietary ... agreement is an amendment to the existing license between ...
(Date:1/14/2014)... York, NY (PRWEB) January 14, 2014 ... of Alliqua, Inc. (OTCQB: ALQA). Alliqua is an emerging ... to serve the wound care market. , Free report ... was restructured with a seasoned management team and Board, ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 iLab Solutions, the ... as the new Director of Product Strategy. In this role, ... as iLab sub-teams to guide in the development of iLab ... provides the maximum possible benefit to the scientific community by ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
Cached News: