HOME >> BIOLOGY >> NEWS
PNNL gathers most complete protein map of 'world's toughest bacterium'

RICHLAND, Wash.--Scientists at the Department of Energy's Pacific Northwest National Laboratory have obtained the most complete protein coverage of any organism to date with the study of a radiation-resistant microbe known to survive extreme environments. This research potentially could open up new opportunities to harness this microorganism, called Deinococcus radiodurans, for bioremediation.

A study published in the Aug. 20 issue of the Proceedings of the National Academy of Sciences observed a 61 percent coverage of the microbe's possible predicted set of proteins, or its proteome. This is the most complete proteome reporting to date of any organism. (The proteome is the collection of proteins expressed by a cell under a specific set of conditions at a specific time.) PNNL scientists identified more than 1,900 proteins in D. radiodurans.

Studying the amount of each protein present at any time has become more important as scientists attempt to learn which proteins are involved in important cellular functions. DOE's Microbial Genome Program, an element of the Genomes to Life Program, provided the genomic information for various microorganisms, including D. radiodurans, and developed ways to predict the set of possible proteins, which hold the key to why and how these microbes carry out different functions.

D. radiodurans is of interest because of its potential to degrade radioactive materials, its ability to withstand high levels of radiation and its impressive DNA repair capabilities. The Guinness Book of World Records once called it the world's toughest bacterium.

"We've been able to see more of the proteins, especially those proteins that exist in small quantities," said Mary Lipton, PNNL senior research scientist and lead author of the PNAS paper. "Because our coverage is unprecedented, we're now able to provide biologists with protein-level information they never had access to before."

To identify proteins involved in va
'"/>

Contact: Staci Maloof
staci.maloof@pnl.gov
509-372-6313
DOE/Pacific Northwest National Laboratory
21-Aug-2002


Page: 1 2

Related biology news :

1. New MIT probe gathers data for better polymers
2. Study of ProCord for neurologically complete spinal cord injury
3. OneWorld Health completes enrollment, treatment in Phase III India trial
4. More than 300 critically endangered species completely unprotected, new study shows
5. Gene-rich human Chromosome 19 sequence completed
6. Laboratory rat gene sequencing completed
7. Pacific Northwest National Lab unveils most complete human blood-plasma proteome map to date
8. More than 700 threatened species remain completely unprotected, new study shows
9. Parasite, mosquito genomes complete malaria picture
10. Research reveals a more complete picture of breast tissue
11. First ever census of jaguars completed

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... Litmus ... an extensive third-party assessment of the company’s security practices has been completed. The ... security regulations. The comprehensive evaluation reviewed Litmus’ processes and systems, assessing them to ...
(Date:8/23/2020)... , ... August 21, 2020 , ... ... Corporation has been published and is now available on the company’s global ... diffraction—serves the X-ray analysis community, presenting current news and crystallographic research. , ...
(Date:8/12/2020)... ... August 11, 2020 , ... Both Roche, based ... entered into license agreements with Housey Pharma’s HMI subsidiary to gain access to ... have annual Research and Development spending in excess of US $10 billion. , ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... SCOTTSDALE, Ariz. (PRWEB) , ... August 13, 2020 ... ... 4254 on its annual Inc. 5000 list, the most prestigious ranking of the ... successful companies within the American economy’s most dynamic segment—its independent small businesses. Intuit, ...
(Date:8/7/2020)... ... August 06, 2020 , ... VGXI, a highly regarded ... on the purchase of greenfield for a new, expanded manufacturing facility. The site ... acres in the initial acquisition, with an option to purchase an additional 21 ...
(Date:7/31/2020)... ... July 29, 2020 , ... G-CON ... of its new tagline, “BUILDING FOR LIFE.” The adoption of this taglines comes ... globe, requiring fast track capacity to provide patients with urgently needed vaccines and ...
(Date:7/31/2020)... ... ... eSource has long been touted as the solution to high data management and ... it did not take off as quickly as people initially expected, and where eSource ... capturing data electronically for clinical trials and then repurposing it for downstream analysis, at ...
Breaking Biology Technology:
Cached News: