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PNNL recognized for commercializing technologies

Richland, Wash. -- The Department of Energy's Pacific Northwest National Laboratory has been recognized for transferring technologies that will enhance drug discovery, treat cancer with fewer side effects, and advance the capabilities of sophisticated analytical instruments known as inductively coupled plasma mass spectrometers for biological and biomedical research.

The Federal Laboratory Consortium is honoring PNNL with three 2004 Excellence in Technology Transfer Awards for the laboratory's Electrodynamic Ion Funnel, alpha particle immunotherapy for treating leukemia and solid-tumor metastases, and Inductively Coupled Plasma/Mass Spectrometry Collision/Reaction Cell Technology.

The PNNL technologies were among 24 recognized nationwide by the FLC this year. With 57 awards, PNNL has been honored by the FLC more than any other federal laboratory since the recognition program began in 1984.

Electrodynamic Ion Funnel

The PNNL-developed Electrodynamic Ion Funnel significantly improves the sensitivity of analytical instruments such as mass spectrometers by improving the focusing and transmission of gaseous ions. Sensitivity is a key measure of the analytical value of a mass spectrometer. Enhanced sensitivity allows, for example, the detection of many new proteins from blood plasma and the possibility of discovering new biomarkers for the early detection of cancer.

The funnel's capability for focusing significantly more ions into the mass spectrometer for analysis will result in lower detection limits, improved data collection, new applications and greater understanding of the substances analyzed.

Originally developed to enhance PNNL's mass spectrometry capabilities, the Electrodynamic Ion Funnel uses a series of ring electrodes of increasingly smaller size in combination with both radio frequency and direct current electric potentials. This provides for the efficient collection of ions in the presence of gases where th
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Contact: Lisa Brown
lisa.brown@pnl.gov
509-375-2465
DOE/Pacific Northwest National Laboratory
1-Mar-2004


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