HOME >> BIOLOGY >> NEWS
'Panning for gold' in the maize genome

ARLINGTON, Va.-- Decoding of a variety of plant genomes could accelerate due to two complementary methods that remove from analysis vast stretches of DNA that do not contain genes.

The approaches, applied jointly in efforts to determine the gene sequences in maize, are described in the Dec. 19 issue of the journal Science. The evaluation of these methods and the assembly of the resulting sequences were undertaken by two groups led by researchers from The Institute for Genomic Research (TIGR) in Rockville, Md., and Cold Spring Harbor Laboratory in New York.

The research was funded by the National Science Foundation's Plant Genome Research Program.

Only about a quarter of the maize genome codes for genes, and these are found in small clusters scattered through a mixture of non-coding DNA and transposons (mobile DNA segments). Two different methods tested by the TIGR group successfully captured parts of the maize genome containing genes. The gene-sequences are of most interest because they provide the specific blueprint for an organism's development, structure and physiology.

With so much non-gene sequence to deal with, it has not been feasible to sequence and assemble the whole maize genome with current technologies. Thus, it is a major shortcut to capture only the portion of the maize sequence containing its genes without having to sequence the entire genome.

"Collecting the maize genes for sequencing is like panning for gold," said Jane Silverthorne, program director for NSF's plant genome program. "Just as gold can be separated from the surrounding rock because it is denser, maize genes can be separated from the surrounding DNA by their chemical and sequence properties."

The first method tested, called methylation filtration, removes sequences that contain a chemical modification (methylation) found on most of the repeated sequences and transposons, leaving behind the proverbial gold of genes.
'"/>

Contact: Sean Kearns
skearns@nsf.gov
703-292-1963
National Science Foundation
18-Dec-2003


Page: 1 2

Related biology news :

1. National Corn Growers Association announces valuable maize genome data now available to scientists
2. Mexican farmers effectively cultivate phenotypic diversity in maize
3. Sequencing project results in six-fold reduction of effective size of maize genome
4. Scientists discover way to streamline analysis of maize genome
5. NSF funds $10.2m maize gene sequencing push
6. Scientists sequence genome of kind of organism central to biospheres carbon cycle
7. Keep genome data freely accessible
8. The book opens on the first tree genome
9. NSF awards 22 new projects for plant genome research
10. Milk genome symposium
11. Environmental decontamination, greenhouse gases, and the genome of a methane-loving bacterium

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/7/2018)... (PRWEB) , ... August 07, 2018 , ... CallTower ... today their new CT Cloud Voice and SIP solutions. CT Cloud solutions are ... secure, quality voice solution that is far superior to traditional PBX systems, at a ...
(Date:8/1/2018)... ... August 01, 2018 , ... Dr. Asher Kimchi, Founder ... winning recipients of the 2018 IAC Awards at the 23rd World Congress on Heart ... also named four faculty to receive the Distinguished Fellowship Awards. , Dr. Asher Kimchi, ...
(Date:8/1/2018)... , ... August 01, 2018 , ... Visikol CEO Dr. ... services and strong pharmaceutical company partnerships that Visikol will far exceed its original 2018 ... developing its suite of digital pathology tools, whole mount imaging ...
Breaking Biology News(10 mins):
(Date:8/9/2018)... ... August 08, 2018 , ... ... was developed and is continually updated by a talented scientific team that includes ... service provides: , 1. Information on the medical impact of a patient’s ...
(Date:8/9/2018)... ... August 09, 2018 , ... Simpson ... construction (AEC) experts with building owners and managers for a full-day discussion on ... Construct symposium comes to Boston for the first time on Thursday, 13 September ...
(Date:7/31/2018)... (PRWEB) , ... July 31, 2018 , ... ... 2 additional CE/IVD marked molecular quality controls to its expanding CE/IVD product inventory. ... controls to our expanding CE/IVD QC offerings. ZeptoMetrix remains entirely committed to fully ...
(Date:7/25/2018)... ... July 25, 2018 , ... Dimitrius Anagnos, an evidence-based ... combat inflammation and autoimmune disorders. , The preclinical research assessed biomarkers for ... was reported:, Over 70% decrease in Interleukin (IL-1ß) ...
Breaking Biology Technology:
Cached News: