HOME >> BIOLOGY >> NEWS
Peering inside the body, with a new spinliterally

COPENHAGEN, Denmark --This story is unabashedly all spin. What's the angle? Why, magic. Its subject--a mouse in a form-fitted Plexiglas tube--performs the honors, spinning like an old phonograph record, at a leisurely one to three revolutions a second, and tilted just so inside a magnetic field being pelted with radio waves. The tiny rodent-adventurer and her cohorts are put under and emerge from the experience no worse for the wear.

This technique, in turn, called slow-magic-angle spinning magnetic resonance spectroscopy, or "slow MAS" for short, has provided researchers a new glimpse inside living tissue and cells that other biomedical imaging methods cannot render. The difference between conventional nuclear magnetic resonance, or NMR, and slow MAS is akin to a near-sighted person looking at a mountain range without his glasses one moment and with glasses the next. Once-indistinguishable peaks and valleys appear, the peaks in this case representing previously unseen biochemical compounds as they appear in living tissues.

"It's a noninvasive way to look at function of living organs and the components at work in them such as fat, glucose and other metabolites," said Robert Wind, a physicist and laboratory fellow at the Department of Energy's Pacific Northwest National Laboratory, and slow-spin technique inventor. "We think this new technique can be used to diagnose diseases and assess the body's response to drugs and even to observe the working physiology of living cells."

Today, at an international nuclear NMR conference (http://www.models.kvl.dk/NMRinFood/), Wind described the technique and experiments that show slow MAS's potential for studying metabolism in muscle and organs. His spinning subject in this case was raw (and very dead) rabbit flesh. He also has taken disembodied mouse livers and brains for slow spins around the magnet, revealing chemical spectra in tissue up to 10 times th
'"/>

Contact: Bill Cannon
cannon@pnl.gov
509-375-3732
DOE/Pacific Northwest National Laboratory
14-Sep-2004


Page: 1 2 3

Related biology news :

1. Peering inside a blood vessel
2. Peering at a machine that pries DNA apart
3. Microbes found in Mayan ruins may deteriorate stone from inside out
4. Scripps scientists look deep inside sharks and their high-performance swimming system
5. IUB scientists to study the ecology of infectious disease -- inside ticks
6. 3-D imaging inside living organism, using quantum dots
7. Automated imaging of brain tissue, high-quality glimpses inside arteries
8. Heart disease among some Japanese may be due to sequencing variation inside a gene
9. Tiny bugs in mealybugs have smaller bugs inside them
10. Buffalo neuroimaging researchers studying multiple sclerosis from inside human brain
11. Farming inside forests hurts bird communities more than timber harvesting, study suggests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... , Apr. 11, 2017 Research and ... Market 2017-2021" report to their offering. ... The global eye tracking market to grow at a ... report, Global Eye Tracking Market 2017-2021, has been prepared based on ... covers the market landscape and its growth prospects over the coming ...
(Date:4/6/2017)... , April 6, 2017 Forecasts ... ANPR, Document Readers, by End-Use (Transportation & Logistics, Government ... Oil, Gas & Fossil Generation Facility, Nuclear Power), Industrial, ... Other) Are you looking for a definitive ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... USA (PRWEB) , ... October 11, 2017 , ... ComplianceOnline’s ... take place on 7th and 8th June 2018 in San Francisco, CA. The Summit ... as well as several distinguished CEOs, board directors and government officials from around the ...
(Date:10/11/2017)... the Netherlands and LAGUNA HILLS, Calif. ... The Institute of Cancer Research, London ... use MMprofiler™ with SKY92, SkylineDx,s prognostic tool to risk-stratify patients ... trial known as MUK nine . The University of ... trial, which is partly funded by Myeloma UK, and ICR ...
(Date:10/11/2017)... ... 11, 2017 , ... Singh Biotechnology today announced that the ... its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B VHH13 single ... the cell membrane and bind intracellular STAT3 and inhibit its function. Dysregulation of ...
(Date:10/10/2017)... ... October 10, 2017 , ... For the second time ... US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled to Washington, D.C. ... US2020. , US2020’s mission is to change the trajectory of STEM education in ...
Breaking Biology Technology:
Cached News: