Penny wise and pound-foolish: Study shows need for second pathologist's opinion

A study of more than 6,000 patients by Johns Hopkins researchers found that one or two out of every 100 people who come to larger medical centers for treatment following a biopsy arrive with a diagnosis that's "totally wrong." The results suggest that second opinion pathology exams not only prevent errors, but also save lives and money.

Patients who fail to receive a second pathologist's exam of their biopsied tissue at the incoming hospital or elsewhere "have a small but significant risk of getting the wrong treatment, including surgery or chemotherapy," says pathologist Jonathan L. Epstein, M.D., who led a Hopkins research team. "That's not to mention the psychological trauma of having the wrong prognosis for an illness," he adds, "or the financial burden of the wrong treatment."

The study appears in the December edition of the journal Cancer.

The team compared the original pathologists' reports that 6,171 patients brought to Hopkins prior to treatment, with additional Hopkins-required pathology reports on the incoming patients. Eighty-six of the patients or 1.4 percent were wrongly diagnosed, Epstein says. "That's not a huge number, percentage-wise," he adds, "but the fact that it's as high as it is remains significant, as does the actual number of patients affected across the country."

In reality, the number of patients misdiagnosed in their original pathology reports is probably closer to 2 percent, Epstein says, because the study didn't consider patients wrongly given a clean bill of health from cancer. Such patients don't typically come to a large medical center for treatment.

The researchers tallied only cases in which the difference in the second report would cause a real change in patients' therapy or in their prognosis. More subtle disparities, such as saying a particular type of cancer was somewhat more advanced, weren't part of the s

Contact: Marjorie Centofanti
Johns Hopkins Medical Institutions

Page: 1 2 3

Related biology news :

1. Study: Emission of smog ingredients from trees is increasing rapidly
2. Study explores gene transfer to modify underlying course of Alzheimers disease
3. Study reveals why eyes in some paintings seem to follow viewers
4. Study by Israeli scientists provides insight on DNA code
5. Study reveals first genetic step necessary for prostate cancer growth
6. Study of flu patients reveals virus outsmarting key drug
7. Study in Science reveals recreational fishing takes big bite of ocean catch
8. Study suggests cell-cycle triggers might be cancer drug targets
9. Study narrows search for genes placing men at increased risk for prostate cancer
10. Study links high carbohydrate diet to increased breast cancer risk
11. Study explains spatial orientation differences between sexes

Post Your Comments:

(Date:6/23/2020)... ... June 23, 2020 , ... Rigaku Corporation ... next event in a series of TOPIQ webinars, which will cover the Transferable ... was developed in response to social distancing measures that resulted in postponements and ...
(Date:6/13/2020)... ... June 11, 2020 , ... Bode Technology (Bode), ... its forensic genealogy team. Bode’s Forensic Genealogy Service (FGS) continues to ... DNA analysis methods. The team has added experienced genealogists, each having over a ...
(Date:6/5/2020)... ... ... Greffex, a pioneering vaccine and gene therapy company based in Houston, Texas, welcomes Mr. ... global perspective to make an impact in a post pandemic world,” said Co-Chairman John ... director of the company. , “The Greffex board is excited to have Neil as ...
Breaking Biology News(10 mins):
(Date:5/15/2020)... ... 15, 2020 , ... Sentien Biotechnologies, Inc., a clinical-stage biotechnology company developing novel ... Mr. Ganz will continue to lead Sentien’s Board of Directors, a role he ... Brian Miller and Sentien’s management team. , Mr. Ganz has more than ...
(Date:5/14/2020)... (PRWEB) , ... May 12, 2020 , ... ... tools for translational research, is bringing together thousands of industry leaders, clinicians, research ... program highlights two plenary speakers, Carl June, MD, Director of the Center for ...
(Date:5/14/2020)... ... May 13, 2020 , ... Early stages of drug discovery ... no information on the drug’s mechanism of action (MOA). Gene expression profiling technologies ... the activity of molecular pathways. This information can complement phenotypic readouts and can ...
(Date:5/5/2020)... ... May 04, 2020 , ... Red Nucleus, ... sciences industry, today announced that Informa Training Partners, a life sciences training company ... Red Nucleus Boston, effective immediately. , “The name change solidifies a stronger presence ...
Breaking Biology Technology:
Cached News: