HOME >> BIOLOGY >> NEWS
Phenotype MicroArray(TM) can test thousands of cell properties simultaneously

Hayward, CA June 26, 2001 A new high-throughput cell analysis tool capable of measuring hundreds to thousands of cellular properties simultaneously has been developed by scientists at Biolog, Inc., who report their work in the July issue of the journal Genome Research. The new Phenotype MicroArrayTM (PM) technology permits the study of a wide range of cell properties (phenotypes) as a means of understanding how a gene or a drug affects living cells a critical step in identifying new drug targets and developing safe and effective new drugs.

The Genome Research article describes the use of PMs to determine the function of genes one of the most important applications of the new technology. Researchers can use PMs to analyze gene function by conducting a very detailed comparison of two cell lines one of which has been modified by a genetic change and directly measuring the cellular response to that change. In Genome Research, Biolog scientists report tests conducted in the cell model bacterium E. coli. Using PMs, the scientists were able to detect the expected changes in cellular response, known as phenotypic changes, associated with genes whose function was already known. More importantly, the PMs were able to detect several unexpected phenotypes as well, leading the researchers to make new discoveries about gene function.

Given the recent explosion of genes sequenced, there is a critical need to quickly, efficiently and accurately characterize and sort through the thousands of genes that are now proposed as potential drug targets, said Barry Bochner, Ph.D., Biolog chairman and vice president of research and development. By providing rapid and detailed answers to how a gene of unknown function affects a cell at the physiological level, Phenotype MicroArrays can greatly accelerate the critical step of evaluating potential drug targets. In addition, this technology can help to protect biological discoveries, since the ability to patent a gen
'"/>

Contact: Tim Mullane
tmullane@biolog.com
510-785-2564 x319
Biolog, Inc.
25-Jun-2001


Page: 1 2 3

Related biology news :

1. Daily vitamins could prevent vision loss among thousands
2. Scientists at TSRI identify thousands of proteins associated with deadliest form of malaria
3. White sharks migrate thousands of miles across the sea, new study finds
4. Wind-borne pollutants may travel thousands of miles
5. Findings of novel nanoproperties in selenium produced by bacteria open new area of exploration
6. Alcohols pharmacological properties, not smell or taste, reinforce its effects
7. Green tea boosts antimicrobial properties of toothpaste
8. MITs smart surface switches properties reversibly
9. Invariant properties in coevolutionary networks of plant-animal interactions
10. Purdue creates self-generating nanotubes with dial-up properties
11. NIST chemists define and refine properties of plastic microsystems

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/5/2020)... ... March 05, 2020 , ... In September 2016, ... The AlphaSTEM Test™ is the first, and still only, available technology that provides ... attempt to provide information about the number and quality of therapeutic tissue stem ...
(Date:3/4/2020)... ... March 04, 2020 , ... VGXI, Inc., a ... has been nominated as a finalist in the category of Best Contract Manufacturing ... VGXI expedites manufacturing of a DNA vaccine against the novel coronavirus, COVID-19, under ...
(Date:3/3/2020)... ... 2020 , ... Board-certified oral and maxillofacial surgeon, Dr. Michael Noffze offers experienced ... and experience, Dr. Noffze can successfully extract problem and impacted wisdom teeth in teens ... beneficial to the oral and overall health of most patients as these extra teeth ...
Breaking Biology News(10 mins):
(Date:3/19/2020)... ... March 18, 2020 , ... Family ... signals to provide rapid insight into their perceptions of events. Imagine if a ... other. What if they could measure the level of engagement of each individual ...
(Date:3/12/2020)... (PRWEB) , ... March 12, 2020 , ... ... of atomic force microscopy (AFM) technology, increases the business investment in Europe by ... , The Grand Opening Ceremony of the new Nanoscience Center Europe took ...
(Date:3/10/2020)... ... March 10, 2020 , ... ... is pleased to announce the addition of Carson Dickey to its growing ... validation in the biopharmaceutical cold chain. He provides design and validation engineering ...
(Date:3/4/2020)... (PRWEB) , ... March 04, ... ... , an industry-leading provider of recombinant antibody products and services, today announced ... customers the flexibility to rapidly express a large number of antibodies at ...
Breaking Biology Technology:
Cached News: