HOME >> BIOLOGY >> NEWS
Polymers promote nerve regeneration

AMES, Iowa Using microscale channels cut in an ultrathin biodegradable polymer, a researcher at the U.S. Department of Energy's Ames Laboratory is working to regrow nerve cells. The technique, which may one day allow the paralyzed to walk and the blind to see, has been proven to work for peripheral nerve regeneration in laboratory rats.

Nerve cells are unlike most other biological tissue. When a nerve is severed, the part of the neuron "downstream" of the injury typically dies off. And neurons in the human body can be several feet long. Grafting, which works well for other tissue such as skin, isn't the best option because of loss of nerve function where the donor tissue is removed and the difficulty in getting the nerve cells to line up and reconnect.

"Nerve cells aren't able to easily bridge gaps of more than one centimeter," says Surya Mallapragada, an Ames Laboratory associate in Materials Chemistry and a chemical engineering professor at Iowa State University. "Peripheral nervous system (PNS) axons the part of the nerve cell which carries the impulses normally have a connective tissue sheath of myelin guide their growth, and without that guidance, they aren't able grow productively."

Since the nervous system carries electrical impulses, it helps to think of nerve cells in terms of electrical wiring. Bundles of nerves are like an electrical cable with multiple wires. When a nerve "cable" is cut and cells die, it would be as though the copper wire downstream of the damage disappeared, leaving only the empty plastic insulation tubes. In order for new copper wiring to push out across the gap and fill in the empty insulation tubes, you'd need a way to guide the wires into the empty insulation. And that's where Mallapragada's research comes in.

By working on a cellular scale, she has developed a way to help guide neurons so they grow in the right direction. Starting with biodegradable polymer films only a few hundred microns thick (
'"/>

Contact: Surya Mallapragada
suryakm@iastate.edu
515-294-7407
DOE/Ames Laboratory
12-Feb-2003


Page: 1 2 3

Related biology news :

1. Reversible Process For Forming Supramolecular Polymers Could Be The Basis Of Fibers, Molecular Transport Mechanisms
2. Model Polymers Reveal New Clues to Protein Folding
3. Dr. Brenda Milner promoted to Companion of the Order of Canada
4. Increased atmospheric carbon dioxide promotes algal growth
5. Symbiotic fungi promote invasion into diverse plant communities (Rudgers et al.)
6. Symbiotic fungi promote invasion into diverse plant communities (Rudgers et al.)
7. Estrogen promotes gender differences in brains response to stress
8. Cell death promotes learning growth
9. Grant promotes marine ornamental fish aquaculture
10. Study suggests ovarian cancer cells can alter surroundings to promote chemotherapy resistance
11. Body hormone ghrelin, a food intake and weight gain influence, is found to promote sleep

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... its 2016 Annual Report on Form 10-K on Thursday April 13, ... ... the Investor Relations section of the Company,s website at http://www.nxt-id.com ... http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... DUBLIN , Apr. 11, 2017 Research ... Tracking Market 2017-2021" report to their offering. ... The global eye tracking market to grow at ... The report, Global Eye Tracking Market 2017-2021, has been prepared based ... report covers the market landscape and its growth prospects over the ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... ... a basic first aid supply for any work environment, but most personal eye wash can ... a dangerous substance enters both eyes? It’s one less decision, and likely quicker response time ... , “Whether its dirt and debris, or an acid or alkali, getting anything in your ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... pathology, announced today it will be hosting a Webinar titled, “Pathology is going ... Pathology Associates , on digital pathology adoption best practices and how Proscia improves ...
(Date:10/11/2017)... Netherlands and LAGUNA HILLS, Calif. ... Institute of Cancer Research, London (ICR) ... MMprofiler™ with SKY92, SkylineDx,s prognostic tool to risk-stratify patients with ... known as MUK nine . The University of ... which is partly funded by Myeloma UK, and ICR will ...
(Date:10/11/2017)... ... October 11, 2017 , ... A ... pregnancy rates in frozen and fresh in vitro fertilization (IVF) transfer ... age to IVF success. , After comparing the results from the fresh and ...
Breaking Biology Technology:
Cached News: