ing. In those with confirmed significant CAD, 39 percent had chest pain relief from nitroglycerin, compared with 38 percent of patients who showed no evidence of coronary artery disease. Among those diagnosed with CAD, just 34.6 percent with a known history of CAD or newly diagnosed with CAD had chest pain relief from nitroglycerin. The frequency of diabetes, traditional CAD risk factors and medication use was similar in patients with or without chest pain relief from nitroglycerin.

Charles A. Henrikson, M.D., first author of the study and a cardiology fellow at Hopkins, says, "Nitroglycerin is still fine to use for patients with chest pain, but physicians must follow them through additional testing to determine whether they truly have CAD."

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Contact: Karen Blum
kblum@jhmi.edu
410-955-1534
Johns Hopkins Medical Institutions
13-Nov-2001

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