HOME >> BIOLOGY >> NEWS
Possible new cure for psoriasis

This press release is also available in German.

Cell biologists of the University of Bonn, in cooperation with the University of Leeds (U.K.) and industry may have discovered a new effective therapy for psoriasis: a specific group of what are known as metalloproteinase inhibitors can normalise the increased tendency of epidermis cells (keratinocytes) to divide, which is the cause of this unpleasant lepidosis. The researchers were not able to detect any toxic side-effects, at least not in cell cultures. Their findings are now being published in the Journal of Investigative Dermatology (Vol. 123, No. 3).

About two million Germans suffer from psoriasis (from the Greek psora meaning 'itching, scratching'). In this incurable disease the regeneration of the epidermis is speeded up enormously: whereas it normally renews itself in just under four weeks, this period is cut to four to seven days in psoriasis patients. The reason is the greatly increased rate of cell division of the keratinocytes. They form a layer which separates the epidermis from the dermis, which lies beneath it. The ageing cells pass from this germinal layer to the surface until they finally scale off.

The disease progresses in waves. Its typical features are clearly defined red areas which are covered with silvery white scales. In the Middle Ages they were thought to be the symptoms of leprosy; a large number of the 'lepers' who were persecuted and even burnt were probably suffering from psoriasis, which is not contagious. What is worse than the changes to the skin itself is the stigma attached to the disease: 'During one of the periods when the disease is more intense many patients think that it is unreasonable to expect people to put up with their presence,' the Bonn cytobiologist Professor Volker Herzog explains. 'Some patients withdraw completely; depressions are not infrequent.'


'"/>

Contact: Professor Volker Herzog
Herzog@uni-bonn.de
49-228-735-301
University of Bonn
16-Aug-2004


Page: 1 2 3

Related biology news :

1. Possible link discovered between gene responsible for blood vessel development and ACD in newborns
2. Possible mechanism for link between diabetes and Alzheimers disease discovered
3. Scientists switch components in cell circuits: Possible new technology, therapy
4. Possible new cell type found in developing inner ear
5. Possible gene for form of mental retardation, brain development identified
6. Possible cause and treatment for shock uncovered by UC San Diego bioengineers
7. Reproductive Signals Affect Lifespan In Roundworm C. Elegans, Offering Possible Insight Into Human Aging Process
8. UV Rays, Fire And Flame Retardants To Be Reviewed For Possible Listing As Carcinogens, NTP Announces
9. Coffee Without Addiction, Possible New Treatment For Osteoporosis, Wrinkle-Free Cotton, And More
10. Mechanism For Fungal Adherence Found, Possible Key To Disease
11. UI Researchers Find Possible Genetic Link Between The X Chromosome And Ovarian Cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced Design ... will feature emerging and evolving technology through its ... Summits will run alongside the expo portion of the ... panels and demonstrations focused on trending topics within 3D ... design and manufacturing event will take place June 13-15, 2017 ...
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... RPS ... clinical study that demonstrates the accuracy of the FebriDx® test, a commercially-ready, ... acute bacterial and viral respiratory tract infections by testing the body’s immune ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and chief research ... Inc. has been selected for membership in ARCS Alumni Hall of Fame ...
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia Inc ., a ... Webinar titled, “Pathology is going digital. Is your lab ready?” with Dr. Nicolas ... practices and how Proscia improves lab economics and realizes an increase in diagnostic ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... the implantation and pregnancy rates in frozen and fresh in vitro fertilization ... progesterone and maternal age to IVF success. , After comparing the results from ...
Breaking Biology Technology:
Cached News: