HOME >> BIOLOGY >> NEWS
Potent new compound from blue-green algae may help treat, elucidate nerve disorders

Click here for abstract.

HONOLULU, Dec. 19 - Amid a growing list of biologically useful chemicals from the sea, a newly discovered compound - kalkitoxin - stands out for its potential to help researchers understand nerve function, which could someday lead to new treatments for pain, epilepsy and possibly stroke. The finding was reported here today at the 2000 International Chemical Congress of Pacific Basin Societies.

The weeklong scientific meeting, held once every five years, is hosted by the American Chemical Society, in conjunction with its counterparts in Australia, Canada, Japan and New Zealand.

Lead investigator William Gerwick, Ph.D., a pharmacy professor at Oregon State University in Corvallis, says the neurotoxin - a metabolite in cyanobacteria - is fundamentally new in both structure and potency.

"What we've found is a spectacularly potent neurotoxin, meaning kalkitoxin can kill neurons," explained Gerwick. "And when a compound is very toxic, it's working by a very specific mechanism." He and his collaborators hope to use that mechanism "to dissect neurochemical pathways and to understand how drugs affect them," he said.

Their discovery began "in an absolutely beautiful bay" of the Caribbean island of Curacao, near Venezuela, Gerwick said. "In 1994, we found a collection of cyanobacteria growing like hairs off the sea floor. We brought several liters of it back to Oregon for testing." Marine cyanobacteria, also called blue-green algae, are most familiar to many people as "pond scum."

Back in the laboratory, Gerwick's team ground up samples of the simple plant and tested extracts on brine shrimp and fish. One extract proved toxic even in concentrations of parts per billion. The researchers named the as-yet-mysterious compound after the island's Kalki Bay
'"/>

Contact: Charmayne Marsh
y_marsh@acs.org
808-944-6381
American Chemical Society
18-Dec-2000


Page: 1 2

Related biology news :

1. Potential for enhanced sequestration of carbon in soils supports evaluations
2. Potent toxin reveals new antibiotic resistance mechanism
3. Potential blood test for colon cancer risk
4. Potential new treatment for Gaucher disease developed by scientists at Scripps Research Institute
5. Potential cause of arthritis discovered
6. Potential of regenerative medicine explored
7. Potential therapy reported for children, adults with end-stage liver disease
8. Potential allergy vaccine boosts hope for sufferers
9. Potential of tailoring drugs to genetic makeup confirmed--but challenges remain
10. Potential new anthrax therapy discovered
11. Potential gene therapy carriers created that mimic viruses, without the risk

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/15/2016)... 2016  A new partnership announced today will ... decisions in a fraction of the time it ... high-value life insurance policies to consumers without requiring ... Force Diagnostics, rapid testing (A1C, Cotinine and HIV) ... pressure, weight, pulse, BMI, and activity data) available ...
(Date:4/13/2016)... 2016  IMPOWER physicians supporting Medicaid patients in ... clinical standard in telehealth thanks to a new partnership ... platform, IMPOWER patients can routinely track key health measurements, ... index, and, when they opt in, share them with ... a local retail location at no cost. By leveraging ...
(Date:3/29/2016)... 29, 2016 LegacyXChange, Inc. (OTC: ... and SelectaDNA/CSI Protect are pleased to announce our successful ... a variety of writing instruments, ensuring athletes signatures against ... collectibles from athletes on LegacyXChange will be assured of ... DNA. Bill Bollander , CEO states, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... NEW YORK , June, 23, 2016  The ... students to envision new ways to harness living systems ... of Modern Art (MoMA) in New York ... more than 130 participating students, showcased projects at MoMA,s ... included Paola Antonelli , MoMA,s senior curator of ...
(Date:6/23/2016)... ON (PRWEB) , ... June 23, 2016 , ... STACS ... DNA Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as ... the STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In ...
(Date:6/23/2016)... June 23, 2016  Blueprint Bio, a company dedicated ... the medical community, has closed its Series A funding ... . "We have received a commitment from ... we need to meet our current goals," stated ... the runway to complete validation on the current projects ...
(Date:6/23/2016)... ... 23, 2016 , ... ClinCapture, the only free validated electronic ... showcase its product’s latest features from June 26 to June 30, 2016 for ... Disrupting Clinical Trials in The Cloud during the conference. DIA (Drug Information ...
Breaking Biology Technology:
Cached News: