HOME >> BIOLOGY >> NEWS
Potential allergy vaccine boosts hope for sufferers

Australian scientists have developed a potential vaccine for hayfever and other pollen related allergies.

The breakthrough could provide a lifeline to the 25 percent of the world's population suffering severe allergic responses to pollen.

Working with a rye grass protein - one of the most potent environmental allergens known - the team, from the University of Melbourne's Plant Molecular Biology and Biotechnology Group, has modified the gene responsible for its production.

The modified gene produced a protein that has a significantly reduced allergenic response, yet one still capable of boosting a person's immune response. These twin features are the key to a potential vaccine, or effective immunotherapy - the practice of giving allergic patients small, but increasing doses of allergen-containing extracts to boost their immunity to the allergen.

"Skin prick tests to assess the protein's safety suggest it is a significantly safer and more effective alternative to the current immunotherapy used to treat grass pollen allergies," says Associate Professor Prem Bhalla, joint leader of the group.

Their research is published in the latest European Journal of Immunology.

Current immunotherapy carries a significant risk of lethal side effects that include anaphylactic shock, a condition where the body rapidly becomes hypersensitive to an allergen.

"The symptoms of allergenic disease, like asthma, hayfever, allergic dermatitis and conjunctivitis, can be controlled with drugs, but specific immunotherapy is the only way to treat the causes of allergies that produce a potentially life threatening hypersensitivity (Type 1 allergies), says Bhalla.

Since its introduction in 1911, immunotherapy therapy has been subject to criticism and debate largely because the underlying immunological mechanisms of the human body are still unknown and because there has been no way of controlling the contents of the allergen-containing
'"/>

Contact: Jason Major
jmajor@unimelb.edu.au
61-3-8344-0181
University of Melbourne
6-Feb-2002


Page: 1 2 3

Related biology news :

1. Potential for enhanced sequestration of carbon in soils supports evaluations
2. Potential blood test for colon cancer risk
3. Potential new treatment for Gaucher disease developed by scientists at Scripps Research Institute
4. Potential cause of arthritis discovered
5. Potential of regenerative medicine explored
6. Potential therapy reported for children, adults with end-stage liver disease
7. Potential of tailoring drugs to genetic makeup confirmed--but challenges remain
8. Potential new anthrax therapy discovered
9. Potential gene therapy carriers created that mimic viruses, without the risk
10. New Class Of Synthetic Capsules That Mimic Biological Cells Has Wide Array Of Potential Uses
11. Role Of Protein Linked To Colon Cancer Identified, Offering Potential Target For Therapy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2019)... ... 29, 2019 , ... FileWave, the multi-platform endpoint management solution ... of version 13.1. The new version extends FileWave’s mobile device management features on ... release functionality. Version 13.1 builds on FileWave’s version 13 that was released in ...
(Date:5/31/2019)... ... ... Enso Discoveries Chief Executive Officer, Patrick Farley, is honored to give back to ... his gratitude and respect for those who have served their country. In honor of ... presented a check for $1,000 to the Green Beret Foundation, via former US Army ...
(Date:5/24/2019)... WOODLANDS, Texas (PRWEB) , ... May 24, 2019 , ... ... been published and is now available on the company’s global website. , Crystallography Times ... on single crystal X-ray diffraction. It serves the X-ray analysis community by presenting the ...
Breaking Biology News(10 mins):
(Date:5/2/2019)... , ... May 02, 2019 , ... Stay on top ... medical device and food industries. Access to all webinars is free, so be sure ... in your field! , Visit http://www.xtalks.com to see our upcoming webinars: , ...
(Date:4/25/2019)... ... , ... Frank is an albino, deaf Great Dane. His owners rescued him when he was ... issues. Despite his hearing impairment, he was always an active and playful pup. Frank bonded ... every day. As the two grew, playtime became rougher and Frank ended up injuring his ...
(Date:4/16/2019)... ... April 16, 2019 , ... ... their project partner, the U.S. Army Center for Environmental Health Research (USACEHR), with ... Combined In-Licensing/Out-Licensing.” , Blue Sources, a veteran-owned company located at the Frederick Innovative ...
(Date:4/12/2019)... , ... April 12, 2019 , ... ... developments in neurotechnology and will educate about innovative tools and devices being used ... local listings for more information. , This segment of Advancements will focus on ...
Breaking Biology Technology:
Cached News: