HOME >> BIOLOGY >> NEWS
Potential allergy vaccine boosts hope for sufferers

Australian scientists have developed a potential vaccine for hayfever and other pollen related allergies.

The breakthrough could provide a lifeline to the 25 percent of the world's population suffering severe allergic responses to pollen.

Working with a rye grass protein - one of the most potent environmental allergens known - the team, from the University of Melbourne's Plant Molecular Biology and Biotechnology Group, has modified the gene responsible for its production.

The modified gene produced a protein that has a significantly reduced allergenic response, yet one still capable of boosting a person's immune response. These twin features are the key to a potential vaccine, or effective immunotherapy - the practice of giving allergic patients small, but increasing doses of allergen-containing extracts to boost their immunity to the allergen.

"Skin prick tests to assess the protein's safety suggest it is a significantly safer and more effective alternative to the current immunotherapy used to treat grass pollen allergies," says Associate Professor Prem Bhalla, joint leader of the group.

Their research is published in the latest European Journal of Immunology.

Current immunotherapy carries a significant risk of lethal side effects that include anaphylactic shock, a condition where the body rapidly becomes hypersensitive to an allergen.

"The symptoms of allergenic disease, like asthma, hayfever, allergic dermatitis and conjunctivitis, can be controlled with drugs, but specific immunotherapy is the only way to treat the causes of allergies that produce a potentially life threatening hypersensitivity (Type 1 allergies), says Bhalla.

Since its introduction in 1911, immunotherapy therapy has been subject to criticism and debate largely because the underlying immunological mechanisms of the human body are still unknown and because there has been no way of controlling the contents of the allergen-containing
'"/>

Contact: Jason Major
jmajor@unimelb.edu.au
61-3-8344-0181
University of Melbourne
6-Feb-2002


Page: 1 2 3

Related biology news :

1. Potential for enhanced sequestration of carbon in soils supports evaluations
2. Potential blood test for colon cancer risk
3. Potential new treatment for Gaucher disease developed by scientists at Scripps Research Institute
4. Potential cause of arthritis discovered
5. Potential of regenerative medicine explored
6. Potential therapy reported for children, adults with end-stage liver disease
7. Potential of tailoring drugs to genetic makeup confirmed--but challenges remain
8. Potential new anthrax therapy discovered
9. Potential gene therapy carriers created that mimic viruses, without the risk
10. New Class Of Synthetic Capsules That Mimic Biological Cells Has Wide Array Of Potential Uses
11. Role Of Protein Linked To Colon Cancer Identified, Offering Potential Target For Therapy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... , ... July 01, 2020 , ... ... awareness and solutions for glioblastoma—the most common and aggressive adult brain cancer—announced today ... JD, PhD. Senior Fellows are charged with supporting the organization’s initiatives and overall ...
(Date:6/25/2020)... Mass. (PRWEB) , ... June 24, 2020 , ... ... of cloud-based enterprise software and software-driven clinical data services that accelerate drug development, ... for low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This ...
(Date:6/23/2020)... ... 2020 , ... The field of quantitation of large molecules or proteins has ... area. However, the use of mass spectrometry in this field has gained a lot ... do you choose which approach to use (LBA or MS)?” In many cases, ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... ... June 30, 2020 , ... ... insights, today announced that the launch of a new clinical diagnostics ... about the tumor microenvironment (TME). , “Flagship’s TissueInsight is a service that ...
(Date:6/28/2020)... ... June 25, 2020 , ... With ... a vaccine or drug treatment. In an effort to better understand the cellular ... the world’s largest imaging dataset portraying therapeutic compound effects from over 1,600 approved ...
(Date:6/28/2020)... SILVER SPRING, Md. (PRWEB) , ... June 26, ... ... the leading trade association representing security solutions providers, today announced its strong opposition ... . , The bill would impose a blanket ban on most federal use ...
(Date:6/23/2020)... ... June 23, 2020 , ... DeCurtis Corporation, the premier provider ... Derek Fournier has been appointed CEO and President. Founder and former CEO, David ... , “DeCurtis Corporation has been on an incredible journey for the last twenty ...
Breaking Biology Technology:
Cached News: