Predictive testing for hereditary breast and ovarian cancer: its effect on women

One in ten women opted to have prophylactic mastectomy and nearly half opted to have their ovaries removed in the year following genetic tests which showed they were at risk of hereditary breast and ovarian cancer (HBOC), a Belgian clinical psychologist reported at the 3rd European Breast Cancer Conference in Barcelona today (Wednesday 20 March).

However Ms Erna Claes, who is studying the impact of predictive testing for HBOC, found that women who had been diagnosed as carriers were not significantly more or less distressed after the results of the predictive genetic testing than women who were found not to be carriers. Nor were there significant differences in distress levels before and after the results of genetic testing in either carriers or non-carriers, according to Ms Claes, a clinical psychologist at the Psychosocial Genetics Unit in Leuven, Belgium.

Instead the carriers took practical measures, following the screening recommendations and opting for regular medical examinations. About 10% had a prophylactic mastectomy within a year of the test result. Of the women who were carriers and aged over 35, 37% had had their ovaries removed (oophorectomy) before applying for predictive testing and 44% had prophylactic oophorectomy after the testing.

Ms Claes said there could be a number of reasons why the women reacted in the way that they did. Within our current study group, only a minority of women have chosen to have a prophylactic mastectomy so far. The majority seem to find this procedure too far reaching or consider it will have too much impact on their lives, their partner or their sexual relations. However, long-term follow-up results are needed in order to see whether more women will choose to have prophylactic mastectomy after the predictive genetic test result. It is possible that what happens in their families could have an impact on their choice, for instance if their sister, mother or aunt is diagnosed with breast or ovar

Contact: Emma Mason
Federation of European Cancer Societies

Page: 1 2 3

Related biology news :

1. Far more men than women favor routine paternity testing at birth
2. Nucleic acid-amplification testing further safeguards nations blood supply
3. Clinical judgement still counts strongly alongside genetic testing
4. Genetic testing of embryos to pick savior sibling OK with most Americans
5. Annual bioethics forum to explore genetic testing
6. New toxicity test could cut animal testing
7. Revised guidelines published for testing for hereditary type of colorectal cancer
8. Study calls for end to age thresholds for prenatal genetic testing
9. Genetic testing of embryos
10. HPV testing could be future strategy for primary screening for cervical cancer
11. High-risk women welcome genetic testing for breast cancer gene

Post Your Comments:

(Date:8/6/2019)... ... August 06, 2019 , ... A ... system that could have far-reaching implications for personalized medicine, especially when seeking treatments ... is able to predict which stem cell donors and manipulation methods might yield ...
(Date:8/4/2019)... ... ... Stay on top of current hot topics through free webinars presented by leading experts ... so be sure to register today to save your place! Participate in the discussion ... upcoming webinars: , CLINICAL OPERATIONS , August 27 – Friend or Foe? An Assessment ...
(Date:8/1/2019)... ... 31, 2019 , ... Molecular Devices, LLC, a leader in ... of its FLIPR® Penta High-Throughput Cellular Screening System. , The new FLIPR Penta ... G-protein-coupled receptors (GPCRs) and ion channels, offering a new high-speed camera option capable ...
Breaking Biology News(10 mins):
(Date:6/12/2019)... TOWNSHIP, N.J. (PRWEB) , ... June 12, 2019 ... ... of custom built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, Medical Device ... with Shanghai Zillion has been signed. The agreement will grant exclusive rights for ...
(Date:6/11/2019)... ... June 10, 2019 , ... DeepDyve and ... scientific journals to DeepDyve’s rental service for peer-reviewed journals. , IOPP’s portfolio ... more than 20 million articles, sourced from more than 15,000 journals. , “By ...
(Date:6/11/2019)... ... June 11, 2019 , ... A study released today in ... are able to incorporate into human CD34+ cells, modifying their gene expression and ... increased the cells’ ability to lodge into bone marrow. This research performed by ...
(Date:5/31/2019)... (PRWEB) , ... May 29, ... ... our patent applications from the USPTO providing proprietary interest to our methodology, ... FOR SLEEP DISORDER DIAGNOSIS AND TREATMENT… extends Somnology’s IP rights including our ...
Breaking Biology Technology:
Cached News: