HOME >> BIOLOGY >> NEWS
Promising hospital anti-infection strategy probably won't work, study shows

Hospital patients increasingly face tenacious bacterial infections because microbes found in hospitals acquire resistance to commonly prescribed antibiotics. A recent strategy alternating the most commonly used antibiotics has sparked hope of stopping the spread of antibiotic resistance.

But a new model shows that the practice of cycling alternating between two or more classes of antibiotics as often as every few months probably will not work. It is an unexpected finding at a time when clinical tests of the practice with real patients are in progress.

"We were really surprised. We expected to find a number of cases where it would work, and it was the exact opposite," said Carl Bergstrom, a University of Washington assistant professor of biology.

Instead of cycling, Bergstrom said, hospitals could probably help patients more by prescribing a variety of antibiotics, a method known as mixing. That means instead of having a standard, rotating antibiotic that is used routinely within a single unit, such as intensive care, or even throughout the hospital, a more effective strategy would be to have two or more generally prescribed antibiotics being administered randomly. Two people sharing a room could routinely receive different antibiotics.

Bergstrom noted that antibiotic mixing already is relatively common, not as a conscious strategy but rather because individual doctors develop preferences for the types of medications they prescribe. That can instigate the same type of antibiotic variety as mixing would introduce.

The theory behind antibiotic cycling is that, just as a pathogen strain begins to adapt to a particular antibiotic, a new antibiotic is introduced and the pathogen must start from scratch in building resistance. However, the model implies that pathogens actually encounter new antibiotics more frequently when hospitals use antibiotic mixing than when they use cycling, so cycling is unlikely to reduce res
'"/>

Contact: Vince Stricherz
vinces@u.washington.edu
206-543-2580
University of Washington
9-Aug-2004


Page: 1 2

Related biology news :

1. Promising research: From employment issues to virology
2. Promising new tool shows how dividing cells finish what they start
3. Promising biomarker for melanoma is identified
4. Promising multi-strain HIV vaccine candidate emerges
5. Promising new therapies for deadly form of leukemia
6. Dr. Robert C. Gallo to Collaborate with Visiting Israeli Scientist on Promising HIV Vaccine Research at Marylands Institute of Human Virology
7. SFU Spin-Off Company To Research Promising Antibacterial Agents
8. SFU Molecular Biologist Pursues Promising New Way To Fight Disease
9. UNC-CH Researchers Develop Promising Heart Research Tool
10. Duke Researchers Call Gene Therapy A Promising Strategy For Sickle Cell Anemia
11. Promising Fatty Acid Research Leads To MS Clinical Trial

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/30/2020)... ... January 30, 2020 , ... Accelera Canada , a full-service firm ... market, is pleased to announce that the company has opened the doors of its ... in 2017. , “We are so thrilled to now have all our partners ...
(Date:1/29/2020)... THE WOODLANDS, Texas (PRWEB) , ... January 29, ... ... clinical grade DNA plasmid, announced it will start production of a DNA vaccine ... an agreement executed with Inovio Pharmaceuticals. A grant of up to $9 million ...
(Date:1/27/2020)... ... January 27, 2020 , ... On Thursday, February 20, ... Life Sciences, Reed Tech and Richard Castle, Global Account Manager Medical Device ... the procedure, other topics include EU MDR timing deadlines, best practices in creating and ...
Breaking Biology News(10 mins):
(Date:2/11/2020)... ... February 11, 2020 , ... ... solutions services in North America, today announced that the City of Fort Worth ... its biosolids management needs. Commencing in April of 2020, Synagro will assume operation ...
(Date:2/5/2020)... Conn. (PRWEB) , ... February 04, 2020 , ... ... develops tools for characterizing microbiome populations down to the strain level, has announced ... will sell Shoreline Biome’s microbiome kits and other products to companies and research ...
(Date:2/3/2020)... ... February 03, 2020 , ... Ovation Travel Group ... Travel, Technology Industry Travel and Biotech/Healthcare Industry Travel Indexes. , All of the ... following statistics:, Average airfare price paid Domestically, Internationally ...
(Date:1/28/2020)... ... January 28, 2020 , ... ... exclusive distributor to food and beverage manufactures within North America. Both Lifecycle and ... This agreement will allow each company to pool their collective resources and provide ...
Breaking Biology Technology:
Cached News: