HOME >> BIOLOGY >> NEWS
Prostate Cancer May Be Predicted 10 Years Before Diagnosis

men with prostate cancer. All men in this study are participants in the BLSA, a longitudinal study of aging established in 1958. They return for follow-up visits every 2 years when they undergo a battery of tests including collection of blood samples. Four years before diagnosis, total PSA was significantly greater for men who developed prostate cancer (5.0ng/ml?0.9) compared to men with BPH (2.8ng/ml?0.3) and controls (0.8 ng/ml?0.1.) Free PSA levels were similar among groups at four years before diagnosis. However, the ratio of free to total PSA continuously decreased among cancer cases over the decade before prostate cancer diagnosis. At a time when total and free PSA levels were similar among groups (8 years before diagnosis), the ratio of free to total PSA was significantly lower for cancer cases (0.13?0.01) compared to BPH (0.17?0.01) and control cases (0.21?0.02). The values that most accurately detected prostate cancer were free to total PSA ratio of ?0.12 when total PSA was between 4.0 - 10.0ng/ml.

"The majority of men who have elevated PSA levels and have further diagnostic tests, such as prostate biopsies, do not have prostate cancer," says Dr. H. Ballentine Carter, a urologist at Johns Hopkins School of Medicine who worked on the study. Dr. Fozard adds, "This study shows that the ratio of free to total PSA may be useful in helping the physician to perdict whether prostate cancer is or is not developing." The American Cancer Society, the American Urological Society, and the American College of Radiology recommend that men have a PSA test and digital rectal exam annually, beginning at age 50. African American men and those with a family history of prostate cancer should have the same tests beginning at age 40. In 1996, an estimated 317,100 new cases of prostate cancer were diagnosed, and prostate cancer was responsible for an estimated 41,400 deaths. Prostate cancer rates are 37 percent higher for black men than white men. Between 1980 and 1990
'"/>

Contact: Suzanne Lewis
MillerM@31.nia.nih.gov
410-558-8114
NIH/National Institute on Aging
31-Dec-1996


Page: 1 2 3

Related biology news :

1. Prostate cancer test works as well for black men, study shows
2. Renowned Prostate Cancer Experts Present Latest Findings At UCSF Cancer Center Symposium
3. Seattle Researchers Zero In On Location Of Gene For Inherited Prostate Cancer; Gene Also Linked To Brain Cancer
4. Common Prostate Cancer: A Different Process Altogether?
5. Plant-Based Fat May Reduce Risk Of Prostate Cancer By Altering Testosterone Metabolism, UB Study Shows
6. Study Of Protein Reveals Two Different Prostate Cancers;One More Deadly Also Shows That Benign Prostate Hyperplasia Not A Precursor To Prostate Cancer
7. Penn Researchers Find Mutation In Prostate Cancer Gene
8. A New Molecular Marker For Prostate Cancer
9. Duration Of Pre-Clinical Prostate Cancer Based On Serial PSA Data From The VA Normative Aging Study
10. PSA Levels Mean More Extensive Prostate Disease In Older Men
11. New Test May Reduce Need For Some Prostate Cancer Biopsies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/4/2020)... , ... July 03, 2020 , ... ... to earn outstanding recognition and multiple awards for not only the products and ... portfolio, SoME® Skincare and Vivace® Microneedle RF. All the brands built by ABM ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... (MBS) has announced a publication detailing the use of its revolutionary NEXTGENPCR ... chain reaction (RT-PCR) in 16 minutes. The article, titled "Ultra-fast one-step RT-PCR ...
(Date:7/1/2020)... , ... July 01, 2020 , ... ... awareness and solutions for glioblastoma—the most common and aggressive adult brain cancer—announced today ... JD, PhD. Senior Fellows are charged with supporting the organization’s initiatives and overall ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 30, 2020 , ... ... software for the life sciences industry, today announced the release of its ... specifically for Medical Science Liaisons (MSLs) and other field medical professionals. ...
(Date:7/18/2020)... ... July 17, 2020 , ... ... firm for the life sciences and food industries, is pleased to announce that ... Clinical Research – Business Development. , Charles is an accomplished and results-driven sales ...
(Date:7/7/2020)... DIEGO (PRWEB) , ... July 06, 2020 , ... R3 ... new program featuring up to 200 million stem cells. Depending on the patient's condition, ... seniors in the US will die having some form of Alzheimers dementia, and the ...
(Date:6/28/2020)... NIGUEL, Calif. (PRWEB) , ... June 25, 2020 , ... ... announced the launch of Safe Space™ for businesses of all types to ensure cleanliness, ... 3D LiDAR. , A Safe Space™ enabled business will provide a health ...
Breaking Biology Technology:
Cached News: