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Protein is key for digestive function of the pancreas

f digestive enzymes in the blood in the pancreases of normal and VAMP8-deficient mice. Compared to normal mice, mice lacking VAMP8 had substantially reduced blood levels of digestive enzymes and demonstrated partial resistance to pancreatitis. This suggests that VAMP8 may be involved in the abnormal secretion of digestive enzymes associated with pancreatitis. Further research is needed to establish whether VAMP8 is directly linked to pancreatitis.


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Contact: Heidi Hardman
hhardman@cell.com
617-397-2879
Cell Press
13-Sep-2004


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