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Protein transforms sedentary muscles into exercised muscles, researchers report

rcise.

"After evaluating the measurements we found that the muscles looked like and functioned as a type I muscle," Bassel-Duby said.

UT Southwestern scientists also performed the muscle-fiber type analysis for today's study and are continuing their own research into the signal transduction pathways that are involved in muscle fiber-type switching.

"The long-term goal of this research is to provide insight and treatment therapy to patients who have muscle fatigue, or are confined to bed rest, to enable them to have stronger, exercised muscles," Bassel-Duby said.

Other UT Southwestern researchers involved in the Nature study were Dr. Eric Olson, chairman of molecular biology, and Dr. Eiji Isotani, a former visiting assistant professor in physiology.


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Contact: Amy Shields
Amy.Shields@UTSouthwestern.edu
214-648-3404
UT Southwestern Medical Center
14-Aug-2002


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