HOME >> BIOLOGY >> NEWS
Protemix corporation announces discovery of way to repair hearts damaged by diabetes

Auckland, New Zealand (August 31, 2004): New Zealand biopharmaceutical company Protemix Corporation has announced the discovery of a treatment which appears to reverse heart disease in people suffering from diabetes and may lead to a more effective intervention in a major cause of death worldwide.

A study1 published in the September issue of the world-leading journal Diabetes shows that six months treatment with the orally active small molecule, LaszarinTM, brought about a significant reduction towards normal heart size in diabetic patients with cardiac enlargement.

Diabetes is often accompanied by enlargement and dysfunction of the heart and coronary heart disease and these are major causes of death2. According to the World Health Organisation, over 194 million people have diabetes.

The research led by Professor Garth Cooper and Dr. John Baker of Protemix demonstrates for the first time that defective metabolism of copper in people with diabetes is implicated in the development of heart disease. LaszarinTM, developed in New Zealand by Protemix, removes the excess copper from the body.

The study in preclinical models and in Phase 2 human clinical trials in subjects with type-2 diabetes, showed that LaszarinTM caused increased urinary output of copper compared with treated controls. The researchers found reversed heart failure in preclinical models. They also found that the damaged hearts in the preclinical models and humans had substantively regenerated after treatment with LaszarinTM .

Professor Cooper explained: 'The next step is to investigate this novel treatment, which is the first in its class, in Phase 3 trials in humans. We are currently submitting our Investigational New Drug Application (IND) to the US Food and Drug Administration (FDA) to enable this process to occur. If successful in Phase 3, LaszarinTM has a potential worldwide market of over tw
'"/>

Contact: Joan Kureczka
JKureczka@comcast.net
415-821-2413
Kureczka/Martin Associates
30-Aug-2004


Page: 1 2

Related biology news :

1. High CO2 levels hamper nitrate incorporation by plants
2. Nonprofits, corporations can collaborate to improve environmental management
3. Secretary of Energy announces seven E.O. Lawrence Award Winners
4. Popular Science announces Third Annual Brilliant 10
5. The American Phytopathological Society announces 2004 awards
6. NSF announces six FIBR awards to tackle some of biologys most challenging questions
7. JGI announces community sequencing program portfolio
8. APS announces the winners of its 2004 postdoctoral fellowship in physiological genomics
9. National Corn Growers Association announces valuable maize genome data now available to scientists
10. DFG announces three percent budget increase
11. Chemical Society announces EPA awards for environmentally friendly technology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... GARDENS, Fla. , April 11, 2017 /PRNewswire/ ... management and secure authentication solutions, today announced that ... by Intelligence Advanced Research Projects Activity (IARPA) to ... IARPA,s Thor program. "Innovation has been ... and IARPA,s Thor program will allow us to ...
(Date:4/5/2017)... 5, 2017  The Allen Institute for Cell Science ... a one-of-a-kind portal and dynamic digital window into the ... the first application of deep learning to create predictive ... lines and a growing suite of powerful tools. The ... and future publicly available resources created and shared by ...
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... , ... San Diego-based team building and cooking events company, Lajollacooks4u, has unveiled ... bold new look is part of a transformation to increase awareness, appeal to new ... , It will also expand its service offering from its signature gourmet cooking classes ...
(Date:10/10/2017)... , ... October 10, 2017 , ... Dr. Bob Harman, ... his local San Diego Rotary Club. The event entitled “Stem Cells ... and had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... innovation and business process optimization firm for the life sciences and healthcare industries, ... conference in San Francisco. , The presentation, “Automating GxP Validation for Agile ...
(Date:10/9/2017)... , ... October 09, 2017 , ... The award-winning American ... broadcast first quarter 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. , ... faced with the challenge of how to continue to feed a growing nation. At ...
Breaking Biology Technology:
Cached News: