HOME >> BIOLOGY >> NEWS
Protemix corporation announces discovery of way to repair hearts damaged by diabetes

Auckland, New Zealand (August 31, 2004): New Zealand biopharmaceutical company Protemix Corporation has announced the discovery of a treatment which appears to reverse heart disease in people suffering from diabetes and may lead to a more effective intervention in a major cause of death worldwide.

A study1 published in the September issue of the world-leading journal Diabetes shows that six months treatment with the orally active small molecule, LaszarinTM, brought about a significant reduction towards normal heart size in diabetic patients with cardiac enlargement.

Diabetes is often accompanied by enlargement and dysfunction of the heart and coronary heart disease and these are major causes of death2. According to the World Health Organisation, over 194 million people have diabetes.

The research led by Professor Garth Cooper and Dr. John Baker of Protemix demonstrates for the first time that defective metabolism of copper in people with diabetes is implicated in the development of heart disease. LaszarinTM, developed in New Zealand by Protemix, removes the excess copper from the body.

The study in preclinical models and in Phase 2 human clinical trials in subjects with type-2 diabetes, showed that LaszarinTM caused increased urinary output of copper compared with treated controls. The researchers found reversed heart failure in preclinical models. They also found that the damaged hearts in the preclinical models and humans had substantively regenerated after treatment with LaszarinTM .

Professor Cooper explained: 'The next step is to investigate this novel treatment, which is the first in its class, in Phase 3 trials in humans. We are currently submitting our Investigational New Drug Application (IND) to the US Food and Drug Administration (FDA) to enable this process to occur. If successful in Phase 3, LaszarinTM has a potential worldwide market of over tw
'"/>

Contact: Joan Kureczka
JKureczka@comcast.net
415-821-2413
Kureczka/Martin Associates
30-Aug-2004


Page: 1 2

Related biology news :

1. High CO2 levels hamper nitrate incorporation by plants
2. Nonprofits, corporations can collaborate to improve environmental management
3. Secretary of Energy announces seven E.O. Lawrence Award Winners
4. Popular Science announces Third Annual Brilliant 10
5. The American Phytopathological Society announces 2004 awards
6. NSF announces six FIBR awards to tackle some of biologys most challenging questions
7. JGI announces community sequencing program portfolio
8. APS announces the winners of its 2004 postdoctoral fellowship in physiological genomics
9. National Corn Growers Association announces valuable maize genome data now available to scientists
10. DFG announces three percent budget increase
11. Chemical Society announces EPA awards for environmentally friendly technology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ARMONK, N.Y. and ITHACA, N.Y. ... IBM ) and Cornell University, a leader in dairy ... combined with bioinformatics designed to help reduce the chances ... breaches. With the onset of this dairy project, Cornell ... the Consortium for Sequencing the Food Supply Chain, a ...
(Date:5/23/2017)... 2017  Hunova, the first robotic gym for the rehabilitation and functional ... in Genoa, Italy . The first 30 robots will ... USA . The technology was developed and patented at ... IIT spin-off Movendo Technology thanks to a 10 million euro investment from ... click: ...
(Date:5/16/2017)... DALLAS , May 16, 2017   ... for health organizations, and MD EMR Systems ... certified development partner for GE, have established a ... Patient Portal product and the GE Centricity™ products, ... Centricity EMR. These new integrations ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 ... London (ICR) and University of ... prognostic tool to risk-stratify patients with multiple myeloma (MM), in ... nine . The University of Leeds ... by Myeloma UK, and ICR will perform the testing services ...
(Date:10/11/2017)... Tampa Bay, Florida (PRWEB) , ... October 11, ... ... Food and Drug Administration (FDA) has granted orphan drug designation to SBT-100, its ... antibody (sdAb) for the treatment of osteosarcoma. SBT-100 is able to cross the ...
(Date:10/10/2017)... ... October 10, 2017 , ... For the ... won a US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled to ... Experience from US2020. , US2020’s mission is to change the trajectory of STEM ...
(Date:10/10/2017)... Calif. , Oct. 10, 2017 SomaGenics ... from the NIH to develop RealSeq®-SC (Single Cell), expected ... for profiling small RNAs (including microRNAs) from single cells ... Program highlights the need to accelerate development of approaches ... "New techniques for measuring levels ...
Breaking Biology Technology:
Cached News: