HOME >> BIOLOGY >> NEWS
Protemix corporation announces discovery of way to repair hearts damaged by diabetes

Auckland, New Zealand (August 31, 2004): New Zealand biopharmaceutical company Protemix Corporation has announced the discovery of a treatment which appears to reverse heart disease in people suffering from diabetes and may lead to a more effective intervention in a major cause of death worldwide.

A study1 published in the September issue of the world-leading journal Diabetes shows that six months treatment with the orally active small molecule, LaszarinTM, brought about a significant reduction towards normal heart size in diabetic patients with cardiac enlargement.

Diabetes is often accompanied by enlargement and dysfunction of the heart and coronary heart disease and these are major causes of death2. According to the World Health Organisation, over 194 million people have diabetes.

The research led by Professor Garth Cooper and Dr. John Baker of Protemix demonstrates for the first time that defective metabolism of copper in people with diabetes is implicated in the development of heart disease. LaszarinTM, developed in New Zealand by Protemix, removes the excess copper from the body.

The study in preclinical models and in Phase 2 human clinical trials in subjects with type-2 diabetes, showed that LaszarinTM caused increased urinary output of copper compared with treated controls. The researchers found reversed heart failure in preclinical models. They also found that the damaged hearts in the preclinical models and humans had substantively regenerated after treatment with LaszarinTM .

Professor Cooper explained: 'The next step is to investigate this novel treatment, which is the first in its class, in Phase 3 trials in humans. We are currently submitting our Investigational New Drug Application (IND) to the US Food and Drug Administration (FDA) to enable this process to occur. If successful in Phase 3, LaszarinTM has a potential worldwide market of over tw
'"/>

Contact: Joan Kureczka
JKureczka@comcast.net
415-821-2413
Kureczka/Martin Associates
30-Aug-2004


Page: 1 2

Related biology news :

1. High CO2 levels hamper nitrate incorporation by plants
2. Nonprofits, corporations can collaborate to improve environmental management
3. Secretary of Energy announces seven E.O. Lawrence Award Winners
4. Popular Science announces Third Annual Brilliant 10
5. The American Phytopathological Society announces 2004 awards
6. NSF announces six FIBR awards to tackle some of biologys most challenging questions
7. JGI announces community sequencing program portfolio
8. APS announces the winners of its 2004 postdoctoral fellowship in physiological genomics
9. National Corn Growers Association announces valuable maize genome data now available to scientists
10. DFG announces three percent budget increase
11. Chemical Society announces EPA awards for environmentally friendly technology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... , March 30, 2017  On April 6-7, 2017, ... the Genome hackathon at Microsoft,s headquarters in ... competition will focus on developing health and wellness apps ... Hack the Genome is the first hackathon ... The world,s largest companies in the genomics, tech and ...
(Date:3/29/2017)... 2017  higi, the health IT company that operates ... America , today announced a Series B investment ... EveryMove. The new investment and acquisition accelerates higi,s strategy ... transform population health activities through the collection and workflow ... higi collects and secures data today on behalf of ...
(Date:3/24/2017)... MILAN , March 24, 2017 The Controller ... Deputy Controller Mr. Abdulla Algeen have received the prestigious international ... Continue Reading ... ... small picture) and Deputy Controller Abdulla Algeen (small picture on the right) ...
Breaking Biology News(10 mins):
(Date:8/11/2017)... (PRWEB) , ... August 11, 2017 , ... Algenist continues ... collagen-based formulation unlocking collagen like never before. , Collagen is the key structural ... to market with Liquid Collagen™, which include: , First ...
(Date:8/10/2017)... NC (PRWEB) , ... August 09, 2017 , ... Each ... Almost half never recover well enough to live an independent lifestyle and, even worse, ... , A new discovery by doctors at the University of California Davis Medical Center ...
(Date:8/10/2017)... ... August 10, 2017 , ... CNA ... outlet had initiated coverage on Next Group Holdings, Inc. and see's significant opportunity ... geared toward those that cannot engage in traditional banking services. According to industry ...
(Date:8/8/2017)... ... August 08, 2017 , ... Cynvenio Biosystems, Inc. ... announced the launch of its second generation PD-L1 expression test. The new blood ... highly sensitive and specific profiling and monitoring of PD-L1 expression on lung cancer ...
Breaking Biology Technology:
Cached News: