HOME >> BIOLOGY >> NEWS
Proteomics and alcoholism research

"Proteomics" refers to the study of proteins that are synthesized by cells, tissues and organs in the body. Recent advances in technology now allow scientists to separate and identify these proteins. According to symposium proceedings published in the February issue of Alcoholism: Clinical & Experimental Research, proteomics has important implications for alcoholism research in terms of identifying biomarkers of alcohol intake, understanding alcohol's effects, particularly on the liver, and developing drugs to treat alcoholism.

"The study of proteins involved in alcoholism has taken two different approaches," said Chinnaswamy Kasinathan, associate professor at the University of Medicine and Dentistry of New Jersey and symposium organizer. "One approach is to select a protein for study because of its role in a pathway believed to involve alcoholism. Since alcoholism is a behavioral disorder, many of the candidate proteins selected for study are involved in neurochemical pathways. An alternate proteomic approach is to study as many proteins as can be separated by a technique such as 2D gel electrophoresis and identified through mass spectrometry. This approach does not select any candidate protein in advance, rather, this approach incorporates and examines the entire proteosome of the body."

The symposium took place at the June 2003 Research Society on Alcoholism meeting in Fort Lauderdale, Florida. Some of the key points were:

  • Research designed to identify a urinary biomarker for alcohol intake has found the presence of two groups of proteins in the urine of alcohol-treated rats but not in the urine of control animals.

    "The ultimate goal of this research is to apply the animal findings to the development of good urinary biomarkers in humans as a measure of alcohol intake," said Kasinathan.

    "This would have important applications for many alcoholism treatment facilities," he added. "For example, there are a
    '"/>




  • 15-Feb-2004


    Page: 1 2 3

    Related biology news :

    1. Proteomics drives new generation of medical treatment
    2. Consortium for Archaeal Genomics and Proteomics established at Penn State
    3. A liking for sweets, combined with novelty seeking, may predict alcoholism
    4. Acamprosate: potential medication for treating alcoholism
    5. Gene linked to alcoholism
    6. Gene therapy reduces drinking in rats with genetic predisposition to alcoholism
    7. A sweet tooth may be a marker for the genetic risk for developing alcoholism
    8. Adult alcoholism and attention-deficit hyperactivity disorder are connected
    9. Researchers find three chromosomal areas with links to alcoholism vulnerability
    10. The eyes have it: Seeking expressions of the genetic risk for developing alcoholism
    11. Investigating a protective gene against alcoholism

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:6/2/2016)... 2, 2016 Perimeter Surveillance & ... Systems, Physical Infrastructure, Support & Other Service  ... offers comprehensive analysis of the global Border ... generate revenues of $17.98 billion in 2016. ... a leader in software and hardware technologies for advanced ...
    (Date:5/24/2016)... 24, 2016 Ampronix facilitates superior patient care by providing unparalleled technology to ... display is the latest premium product recently added to the range of products distributed ... ... ... Imaging- LCD Medical Display- Ampronix News ...
    (Date:5/16/2016)... YORK , May 16, 2016   EyeLock ... solutions, today announced the opening of an IoT Center ... to strengthen and expand the development of embedded iris ... an unprecedented level of convenience and security with unmatched ... authenticate one,s identity aside from DNA. EyeLock,s platform uses ...
    Breaking Biology News(10 mins):
    (Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
    (Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
    (Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
    (Date:6/23/2016)... ... June 23, 2016 , ... ... and technical consulting, provides a free webinar on Performing Quality Investigations: ... 2016 at 12pm CT at no charge. , Incomplete investigations are still a ...
    Breaking Biology Technology:
    Cached News: