HOME >> BIOLOGY >> NEWS
Purdue instrument to fashion custom-made proteomics chips

WEST LAFAYETTE, Ind. - Purdue University scientists are developing an instrument that can fabricate custom-made biochips for protein analysis, offering a potentially powerful new tool for drug development and basic medical research.

The instrument makes use of a new method to remove and isolate the tangle of proteins found within cells, a process necessary to reveal protein function within an organism. In contrast to other, more labor-intensive separation methods, the Purdue team's technique allows proteins with similar chemical properties to be separated in the gas phase based on their mass so that analysis can be accomplished in far fewer steps than previously required.

"This technique, when fully developed, will allow us to take hundreds of proteins from a cell without damaging them," said R. Graham Cooks, the Henry Bohn Hass Distinguished Professor of Analytical Chemistry in Purdue's School of Science. "We can then deposit these proteins in specific locations on a chip, where their functions can be analyzed quickly. We hope this chip-making instrument will streamline proteomics research."

The research involving the separation technique appears in this week's (8/13) online edition of Science.

Proteins are well known as the building blocks for all living things, but within plants and animals there are thousands of varieties of these complex molecules. Each performs a different task - transporting chemicals within cells, for example, or facilitating the transfer of energy.

Categorizing protein function is a young and promising field of biology called proteomics, which many scientists believe will provide untold medical advances over the next few decades. To make such advances, however, scientists must sift through the jumble of proteins inside a cell and isolate each one, which has not been an easy job.

"Proteins form a kind of complex soup inside your cells," said Zheng Ouyang, research scientist and co-author
'"/>

Contact: Chad Boutin
cboutin@purdue.edu
765-494-2081
Purdue University
14-Aug-2003


Page: 1 2 3

Related biology news :

1. Purdue study finds antioxidant protects metal-eating plants
2. Bright idea could doom cancer and viruses, say Purdue scientists
3. Purdue yeast makes ethanol from agricultural waste more effectively
4. IU and Purdue scientists to answer questions about Brood X periodical cicadas
5. Purdue scientists finding ways to outsmart crop-damaging bugs
6. Chestnut trees to spread across landscape again, says Purdue scientist
7. Purdue scientists: To stop cancer, keep your Icmt away from your Ras
8. Purdue chemists put the twist on protein building block
9. Purdue scientists: Genetically modified fish could damage ecology
10. Fat cells fight disease, Purdue University researchers find
11. Purdue chemist mussels in on secrets of natural adhesives

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/30/2017)... 30, 2017 Today, American Trucking Associations ... of face and eye tracking software, became the ... program. "Artificial intelligence and advanced ... monitor a driver,s attentiveness levels while on the ... to detect fatigue and prevent potential accidents, which ...
(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017  Veratad Technologies, LLC ( www.veratad.com ), ... and identity verification solutions, announced today they will participate ... May 15 thru May 17, 2017, in ... Trade Center. Identity impacts the lives ... today,s quickly evolving digital world, defining identity is critical ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... United States multicenter, prospective clinical study that demonstrates the accuracy of the ... of identifying clinically significant acute bacterial and viral respiratory tract infections by ...
(Date:10/11/2017)... ... 2017 , ... At its national board meeting in North ... the co-founder, CEO and chief research scientist of Minnesota-based Advanced Space Technology and ... ARCS Alumni Hall of Fame . ASTER Labs is a technology development ...
(Date:10/11/2017)... ... 11, 2017 , ... Proscia Inc ., a data ... titled, “Pathology is going digital. Is your lab ready?” with Dr. Nicolas Cacciabeve, ... and how Proscia improves lab economics and realizes an increase in diagnostic confidence.* ...
(Date:10/11/2017)... ... October 11, 2017 , ... A ... pregnancy rates in frozen and fresh in vitro fertilization (IVF) transfer ... age to IVF success. , After comparing the results from the fresh and ...
Breaking Biology Technology:
Cached News: