HOME >> BIOLOGY >> NEWS
Purdue instrument to fashion custom-made proteomics chips

WEST LAFAYETTE, Ind. - Purdue University scientists are developing an instrument that can fabricate custom-made biochips for protein analysis, offering a potentially powerful new tool for drug development and basic medical research.

The instrument makes use of a new method to remove and isolate the tangle of proteins found within cells, a process necessary to reveal protein function within an organism. In contrast to other, more labor-intensive separation methods, the Purdue team's technique allows proteins with similar chemical properties to be separated in the gas phase based on their mass so that analysis can be accomplished in far fewer steps than previously required.

"This technique, when fully developed, will allow us to take hundreds of proteins from a cell without damaging them," said R. Graham Cooks, the Henry Bohn Hass Distinguished Professor of Analytical Chemistry in Purdue's School of Science. "We can then deposit these proteins in specific locations on a chip, where their functions can be analyzed quickly. We hope this chip-making instrument will streamline proteomics research."

The research involving the separation technique appears in this week's (8/13) online edition of Science.

Proteins are well known as the building blocks for all living things, but within plants and animals there are thousands of varieties of these complex molecules. Each performs a different task - transporting chemicals within cells, for example, or facilitating the transfer of energy.

Categorizing protein function is a young and promising field of biology called proteomics, which many scientists believe will provide untold medical advances over the next few decades. To make such advances, however, scientists must sift through the jumble of proteins inside a cell and isolate each one, which has not been an easy job.

"Proteins form a kind of complex soup inside your cells," said Zheng Ouyang, research scientist and co-author
'"/>

Contact: Chad Boutin
cboutin@purdue.edu
765-494-2081
Purdue University
14-Aug-2003


Page: 1 2 3

Related biology news :

1. Purdue study finds antioxidant protects metal-eating plants
2. Bright idea could doom cancer and viruses, say Purdue scientists
3. Purdue yeast makes ethanol from agricultural waste more effectively
4. IU and Purdue scientists to answer questions about Brood X periodical cicadas
5. Purdue scientists finding ways to outsmart crop-damaging bugs
6. Chestnut trees to spread across landscape again, says Purdue scientist
7. Purdue scientists: To stop cancer, keep your Icmt away from your Ras
8. Purdue chemists put the twist on protein building block
9. Purdue scientists: Genetically modified fish could damage ecology
10. Fat cells fight disease, Purdue University researchers find
11. Purdue chemist mussels in on secrets of natural adhesives

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Purdue instrument fashion custom made proteomics chips

(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a ... announced that its DigitalPersona ® Pro Enterprise ... have been deployed throughout First Bank branch locations ... South Carolina and Virginia. First Bank, ... Southern Pines, North Carolina , selected ...
(Date:11/21/2014)... , Nov. 19, 2014  Earlier this year ... York College, and one of the most prolific inventors ... that are transmitted from Smartphones to third party agencies. ... and has one of the earliest known patents in ... usage in the military, child care, elder care and ...
(Date:11/18/2014)... WASHINGTON , Nov. 18, 2014  The ... Security Industry Association today jointly announce the formation ... and release of its Identity and Biometric ... (Framework). The Framework received official support from BORDERPOL, ... governments to improve and provide expertise regarding border ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
(Date:12/19/2014)... FL (PRWEB) December 18, 2014 ... the nation’s leading specialty pharmacies, has an expanded ... as clinical pharmacy consultants for prescriber offices in ... expertise. , “We have a variety of ... For example, those specializing in hepatitis C help ...
(Date:12/19/2014)... LayerBio is an MIT spin-off developing ... The National Eye Institute (NEI) at the National Institutes ... SBIR grant to develop a drug-eluting intraocular lens (IOL) ... cause of vision loss in people over age 40 ... Dr. Ken Mandell, LayerBio’s Founder and CEO, "There is ...
(Date:12/19/2014)... 2014 Reports from CDC ... suffer from one or more chronic health conditions - ... can address some of these diseases, but may not ... sufferers face. While implanted nerve stimulation devices today offer ... nerve, which can induce side effects. , To ...
(Date:12/19/2014)... In contrast to traditional LED lights where the ... uses proprietary LED technology to incorporate their spectra in ... is critical in low proximity installations. The Valoya L-series ... lifetime which is up to four times longer than ... cost was clearly higher when compared to traditional fluorescent ...
Breaking Biology Technology:BioPlus Specialty Pharmacy Expands ‘Regional Pharmaceutical Care Liaison’ Team 2BioPlus Specialty Pharmacy Expands ‘Regional Pharmaceutical Care Liaison’ Team 3LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2
Cached News: