HOME >> BIOLOGY >> NEWS
Purdue instrument to fashion custom-made proteomics chips

WEST LAFAYETTE, Ind. - Purdue University scientists are developing an instrument that can fabricate custom-made biochips for protein analysis, offering a potentially powerful new tool for drug development and basic medical research.

The instrument makes use of a new method to remove and isolate the tangle of proteins found within cells, a process necessary to reveal protein function within an organism. In contrast to other, more labor-intensive separation methods, the Purdue team's technique allows proteins with similar chemical properties to be separated in the gas phase based on their mass so that analysis can be accomplished in far fewer steps than previously required.

"This technique, when fully developed, will allow us to take hundreds of proteins from a cell without damaging them," said R. Graham Cooks, the Henry Bohn Hass Distinguished Professor of Analytical Chemistry in Purdue's School of Science. "We can then deposit these proteins in specific locations on a chip, where their functions can be analyzed quickly. We hope this chip-making instrument will streamline proteomics research."

The research involving the separation technique appears in this week's (8/13) online edition of Science.

Proteins are well known as the building blocks for all living things, but within plants and animals there are thousands of varieties of these complex molecules. Each performs a different task - transporting chemicals within cells, for example, or facilitating the transfer of energy.

Categorizing protein function is a young and promising field of biology called proteomics, which many scientists believe will provide untold medical advances over the next few decades. To make such advances, however, scientists must sift through the jumble of proteins inside a cell and isolate each one, which has not been an easy job.

"Proteins form a kind of complex soup inside your cells," said Zheng Ouyang, research scientist and co-author
'"/>

Contact: Chad Boutin
cboutin@purdue.edu
765-494-2081
Purdue University
14-Aug-2003


Page: 1 2 3

Related biology news :

1. Purdue study finds antioxidant protects metal-eating plants
2. Bright idea could doom cancer and viruses, say Purdue scientists
3. Purdue yeast makes ethanol from agricultural waste more effectively
4. IU and Purdue scientists to answer questions about Brood X periodical cicadas
5. Purdue scientists finding ways to outsmart crop-damaging bugs
6. Chestnut trees to spread across landscape again, says Purdue scientist
7. Purdue scientists: To stop cancer, keep your Icmt away from your Ras
8. Purdue chemists put the twist on protein building block
9. Purdue scientists: Genetically modified fish could damage ecology
10. Fat cells fight disease, Purdue University researchers find
11. Purdue chemist mussels in on secrets of natural adhesives

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Purdue instrument fashion custom made proteomics chips

(Date:8/22/2014)... Calif. Thomson Reuters , a leading source ... researchers at the University of California, Riverside in its ... minds of our times." , To generate the list, ... to identify researchers whose published work has had enormous ... among some 3,200 individuals who published the greatest number ...
(Date:8/22/2014)... Jolla, CA Research presented at the 29th ... being developed by Hera Therapeutics Inc. combats three ... cause 70 percent of all cervical cancer. , ... HTI-1968 blocked the replication of HPV-16, HPV-18 and ... and Thomas Broker, Ph.D., who presented the findings ...
(Date:8/22/2014)... news release is available in French . ... drain of essential nutrients from African soils looming as a ... report released today finds that over the last five years, ... practices that have rejuvenated 1.6 million hectares and helped them ... the Alliance for a Green Revolution in Africa (AGRA) focuses ...
Breaking Biology News(10 mins):5 UC Riverside scientists among world's most influential scientific minds 2Effort to confront Africa's soil health crisis helps millions of farmers triple yields 2Effort to confront Africa's soil health crisis helps millions of farmers triple yields 3Effort to confront Africa's soil health crisis helps millions of farmers triple yields 4
(Date:8/21/2014)... , Aug. 21, 2014 Telomere ... of their Nutraceutical "TELO-20 for Dogs" with ... Telomere-lengthening supplement in the world for dogs. Telomeres ... every chromosome in the body. A wealth of ... experts in Telomere Science and Aging, including Nobel ...
(Date:8/21/2014)... 2014  Decision Resources Group finds that the ... and Mexico currently faces ... approved agents, the anticipated label extension of Boehringer ... of emerging biologics will substantially increase the competitiveness ... IL-5 inhibitors will introduce a new dynamic to the ...
(Date:8/21/2014)... YORK , Aug. 21, 2014 ... congratulates Immune Pharmaceuticals Inc., a biotechnology company, on ... Market.  Immune previously traded on OTCQX®, the best ... by OTC Markets Group. Logo - ... Pharmaceuticals on the successful execution of its growth ...
(Date:8/21/2014)... MOUNTAIN VIEW, Calif. , Aug. 21, 2014 ... their properties and behaviors based on external stimuli ... is poised to have a disruptive effect in ... will revolutionize the business landscape by printing objects ... the aerospace and automotive sectors. Logo ...
Breaking Biology Technology:Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 3Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 3OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 4
Cached News: