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Purdue researchers expose 'Docking Bay' for viral attack

likely be easier if we can borrow some mechanisms already proven by nature."

Such applications are admittedly pie in the sky for the moment, and Rossmann said the most valuable result of the research is the fundamental knowledge it reveals about viruses.

"We now have a close-up image of the machinery that guides the steps taken when a virus infects a cell," he said. "We hope further analyses will show even greater detail."

This research was funded in part by grants from the National Science Foundation, the Howard Hughes Medical Institute and the Human Frontiers Science Program.

Rossmann's team is associated with Purdue's Markey Center for Structural Biology, which consists of laboratories that use a combination of cryoelectron microscopy, crystallography and molecular biology to elucidate the processes of viral entry, replication and pathogenesis.


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Contact: Chad Boutin
cboutin@purdue.edu
765-494-2081
Purdue University
18-Aug-2003


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