HOME >> BIOLOGY >> NEWS
Putting muscle in the nucleus

Scientists have long pondered how, inside the nucleus of a cell, long stretches of DNA are moved through the huge enzyme factories that transcribe DNA's genetic information into messages made of RNA. Now, for the first time, a team of scientists from the University of Illinois at Chicago has demonstrated the presence of a "molecular motor" inside the nucleus, where it appears to power the assembly line that forges RNA messages off of the long DNA templates.

The finding is reported in the Oct. 13 issue of the journal Science. The work was funded by the National Science Foundation (NSF), the National Institute of General Medical Sciences (one of the National Institutes of Health), the Czech Ministry of Education and the Academy of Sciences of the Czech Republic.

The motor molecule, called myosin-1, is a close chemical relative of the myosin responsible for muscle contraction.

"When your heart beats, when you take a breath, when you digest food or have a baby - anytime cells move or divide - myosin is involved," says Primal de Lanerolle, professor of physiology and biophysics at UIC, who led the international team.

Myosin, well-known since the 1920s, is a protein found in the cytoplasm of nearly every type of cell in the body. It had never before been found in the nucleus. DNA, on the other hand, resides in the nucleus, where it is transcribed into the RNA messages that then travel to the cytoplasm to guide the synthesis of the proteins - like myosin - that do all the work of the cell.

"This is a very significant development," said Eve Barak, acting deputy director of NSF's Division of Molecular and Cellular Biosciences. "The outcome of this work really underscores the importance of supporting 'risky' science. What started out as a project to substantiate a highly controversial observation - myosin in the nucleus - has turned out to be an important key for understanding just how cells
'"/>

Contact: Ketrina Jackson
kjackson@nsf.gov
703-292-8070
National Science Foundation
11-Oct-2000


Page: 1 2

Related biology news :

1. Putting energy into heart protection
2. Putting GPS to work, researchers shed light on road-following by pigeons
3. Putting genes in a pill
4. Putting microRNAs in their place
5. Putting randomness to work: unique form of nanoscale random motion may drive key cellular functions
6. Putting muscle in the nucleus
7. Putting a price tag on paradise
8. Putting medical research on-line to give patients the information they need
9. Putting Doesnt Pollute, Research Finds
10. Putting A Price Tag On Pollution
11. Putting Down Your Roots: How Plants Know To Do It

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2016)... SAN FRANCISCO , June 16, 2016 /PRNewswire/ ... Market size is expected to reach USD ... report by Grand View Research, Inc. Technological proliferation ... and banking applications are expected to drive the ... ) , The development of ...
(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
(Date:5/24/2016)... Ampronix facilitates superior patient care by providing unparalleled technology to leaders of the medical ... premium product recently added to the range of products distributed by Ampronix. ... ... ... Ampronix News ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... is pleased to announce the launch of their brand, UP4™ Probiotics, into Target ... over 35 years, is proud to add Target to its list of well-respected ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute approval ... of microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the ... at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application ... team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our ...
(Date:6/23/2016)... NEW YORK , June 23, 2016 ... the trading session at 4,833.32, down 0.22%; the Dow Jones ... the S&P 500 closed at 2,085.45, down 0.17%. Stock-Callers.com has ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ... BIND Therapeutics Inc. (NASDAQ: BIND ). Learn more ...
Breaking Biology Technology:
Cached News: