HOME >> BIOLOGY >> NEWS
Putting muscle in the nucleus

Scientists have long pondered how, inside the nucleus of a cell, long stretches of DNA are moved through the huge enzyme factories that transcribe DNA's genetic information into messages made of RNA. Now, for the first time, a team of scientists from the University of Illinois at Chicago has demonstrated the presence of a "molecular motor" inside the nucleus, where it appears to power the assembly line that forges RNA messages off of the long DNA templates.

The finding is reported in the Oct. 13 issue of the journal Science. The work was funded by the National Science Foundation (NSF), the National Institute of General Medical Sciences (one of the National Institutes of Health), the Czech Ministry of Education and the Academy of Sciences of the Czech Republic.

The motor molecule, called myosin-1, is a close chemical relative of the myosin responsible for muscle contraction.

"When your heart beats, when you take a breath, when you digest food or have a baby - anytime cells move or divide - myosin is involved," says Primal de Lanerolle, professor of physiology and biophysics at UIC, who led the international team.

Myosin, well-known since the 1920s, is a protein found in the cytoplasm of nearly every type of cell in the body. It had never before been found in the nucleus. DNA, on the other hand, resides in the nucleus, where it is transcribed into the RNA messages that then travel to the cytoplasm to guide the synthesis of the proteins - like myosin - that do all the work of the cell.

"This is a very significant development," said Eve Barak, acting deputy director of NSF's Division of Molecular and Cellular Biosciences. "The outcome of this work really underscores the importance of supporting 'risky' science. What started out as a project to substantiate a highly controversial observation - myosin in the nucleus - has turned out to be an important key for understanding just how cells
'"/>

Contact: Ketrina Jackson
kjackson@nsf.gov
703-292-8070
National Science Foundation
11-Oct-2000


Page: 1 2

Related biology news :

1. Putting energy into heart protection
2. Putting GPS to work, researchers shed light on road-following by pigeons
3. Putting genes in a pill
4. Putting microRNAs in their place
5. Putting randomness to work: unique form of nanoscale random motion may drive key cellular functions
6. Putting muscle in the nucleus
7. Putting a price tag on paradise
8. Putting medical research on-line to give patients the information they need
9. Putting Doesnt Pollute, Research Finds
10. Putting A Price Tag On Pollution
11. Putting Down Your Roots: How Plants Know To Do It

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/4/2020)... PHOENIX (PRWEB) , ... July 03, 2020 , ... ... is proud to earn outstanding recognition and multiple awards for not only the ... the ABM portfolio, SoME® Skincare and Vivace® Microneedle RF. All the brands built ...
(Date:7/1/2020)... ... 01, 2020 , ... Catalent, a global leader in clinical ... packaging facility in Minakuchi, located in the Shiga prefecture of Japan. , Operating ... the new 60,000-square-foot facility will provide customers with flexible clinical supply solutions, serving ...
(Date:6/28/2020)... (PRWEB) , ... June 25, 2020 , ... In an ... on innovations in accelerated Point of Care Testing solutions (POCT). Check local listings for ... are collected at medical offices and are shipped to labs throughout the country. Results ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet ... to three different materials for use with CRM, neurostimulation, vascular, and related devices. ... to meet specific design requirements, performance, and cost criteria; especially where solid wire ...
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been ... webinar will cover the history of eSource, the reasons it did not take off ... wearables, to site source, the industry is moving towards capturing data electronically for clinical ...
(Date:7/31/2020)... (PRWEB) , ... July 30, ... ... of cloud-based software for the life sciences industry, today announced the release ... platform designed specifically for Medical Science Liaisons (MSLs) and other field medical ...
(Date:7/18/2020)... ... July 16, 2020 , ... After research model surgery and ... a great surgery is only the beginning of a successful study, while protecting and ... Join Brad Gien, Global Head of Surgery from Envigo in a ...
Breaking Biology Technology:
Cached News: