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Racial differences explored in treatment response for hepatitis C

-treatment) between the two treatment groups will be compared to determine differences in treatment response.

Prior to therapy, variables such as gender, history of alcohol use and viral RNA levels will be studied to determine possible factors associated with sustained virological response and how they may differ between the treatment groups.

Potential mechanisms of anti-viral drug resistance will be explored via blood cells sampled from participants at various times in the trial. Among other molecular factors to be studied are measures of interferon signaling pathways and both host and viral genetics.


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Contact: Leslie H. Lang
llang@med.unc.edu
919-843-9687
University of North Carolina School of Medicine
15-May-2002


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