HOME >> BIOLOGY >> NEWS
Rapid movements of living biomolecules visualised

Dutch researcher Chris Molenaar has made the rapid movements of proteins, DNA and RNA molecules visible in living cells. With this technique researchers can study the dynamics of biomolecules in their natural environment.

Molenaar developed a method which makes it possible to follow the movements of RNA molecules in living cells. The researcher also made the movements and interactions between proteins in living cells visible with the aid of the revolutionary "Green Fluorescent Protein".

Much of the present knowledge about molecular compositions of the cell and the mechanisms in which biomolecules such as DNA, RNA and proteins play a role, is based on experiments in tests tubes with biomolecules isolated from cells. However, with these molecules it is difficult to simulate the behaviour in a living cell. Dynamic processes in the cell can only be understood with living cell microscopy.

Molenaar used fluorescent probes which specifically bind to the molecule he wanted to study. By using a fluorescent microscope to examine where a fluorescent molecule was at different times, the movement of the structures containing these molecules could be followed. For example, the researcher followed the tips of chromosomes (telomeres) in three dimensions over the course of time.

The mobility of populations of molecules was visualised using FRAP (Fluorescence Recovery After Photobleaching). The fluorescent molecules in a small part of the cell are destroyed when a laser is focussed on them. However, although it no longer fluoresces, the biomolecule to which the fluorescent molecule is attached remains intact. The rate at which the fluorescent molecules from the surroundings move into this dark area says something about the mobility of, for example, a certain type of RNA or protein. This mobility in turns provides further information about the functioning of the molecules.

In addition to the movement of the biomolecules, Molenaar also visuali
'"/>

Contact: Nalinie Moerlie
news@nwo.nl
31-70-344-0713
Netherlands Organization for Scientific Research
24-Jun-2003


Page: 1 2

Related biology news :

1. Rapidly evolving genes providing new insights in plant evolution
2. Rapid evolution helps hunted outwit their predators
3. Rapid weight gain in infancy may lead to obesity at age 7
4. Worlds largest scientific society convenes its regional meeting June 11-13 in Grand Rapids, Mich.
5. Rapid size change in introduced fruit fly indicates it is evolving as it invades North America
6. Rapid Population Growth Is Still A Problem
7. Ancient Volcanic Winter Tied To Rapid Genetic Divergence In Humans
8. Penn Researchers Invent Worlds First Device To Rapidly Assess Lung Function
9. Northwestern Researchers Develop Rapid Diagnostic Test To Detect Antibiotic-Resistant Bacteria
10. Rapid Progress Reported On New Class Of Anti-Cancer Drugs
11. Virginia Tech Researchers Receive Patent For Rapid Virus Detection Technology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... 2017  Veratad Technologies, LLC ( www.veratad.com ), an ... identity verification solutions, announced today they will participate as ... 15 thru May 17, 2017, in Washington ... Center. Identity impacts the lives of ... quickly evolving digital world, defining identity is critical to ...
(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
(Date:4/13/2017)... According to a new market research report "Consumer IAM Market by Solution ... Authentication Type, Deployment Mode, Vertical, and Region - Global Forecast to 2022", ... 14.30 Billion in 2017 to USD 31.75 Billion by 2022, at a ... ... MarketsandMarkets Logo ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Palo Alto, CA, USA (PRWEB) , ... October 11, 2017 , ... ... is set to take place on 7th and 8th June 2018 in San Francisco, ... and policy influencers as well as several distinguished CEOs, board directors and government officials ...
(Date:10/11/2017)... ... October 11, 2017 , ... Disappearing forests and increased emissions are the ... million people each year. Especially those living in larger cities are affected by air ... one of the most pollution-affected countries globally - decided to take action. , “I ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that ... Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los ...
(Date:10/10/2017)... 10, 2017 SomaGenics announced the receipt of ... develop RealSeq®-SC (Single Cell), expected to be the first ... (including microRNAs) from single cells using NGS methods. The ... to accelerate development of approaches to analyze the heterogeneity ... "New techniques for measuring levels of mRNAs in individual ...
Breaking Biology Technology:
Cached News: