HOME >> BIOLOGY >> NEWS
Recreational use of cocaine promotes blood clots

Cocaine activates platelets and increases the fomation of circulating platelet containing microaggregates in humans

Even occasional use of cocaine promotes the formation of blood clots, shows a study in Heart. This could explain why the risk of heart attacks is so much higher in people who use the drug, the research concludes.

The heart rates and blood chemical responses were monitored in fourteen 23 to 41 year olds up to two hours after having been given 2 mg per kg of body weight of cocaine, equivalent to recreational use and the same amount of a placebo. None of the volunteers had ever used cocaine before.

Compared with the placebo, cocaine slightly increased heart rate and blood pressure. But chemicals which indicate that the blood is "stickier" and which enhance the formation of clots (thrombosis) had significantly increased two hours after cocaine had been taken. And the bleeding time, a measure of how long it takes the blood to form a clot around a wound, had fallen in two thirds of the volunteers.

Bleeding of the linings of the nose and stomach is a frequent side-effect of snorting coke, say the authors, a factor which is not usually associated with thickening of the blood. But they say, cocaine has a systemic effect that has nothing to do with when or how the drug is taken. And it sets off a chain of events in the blood that promote clots, making the user susceptible to heart attacks.

"The data...add to mounting evidence disproving the widely held belief that occasional cocaine abuse poses little risk. The risk of thrombosis, similar to the risk of sudden cardiac death, is real and may affect even the first time user of small quantities of the drug."


'"/>

Contact: BMA Press Office
pressoffice@bma.org.uk
440-207-383-6254
BMJ Specialty Journals
14-May-2000


Page: 1

Related biology news :

1. Recreational use of the drug Ecstasy causes new kind of brain damage
2. Genes may be central to cocaine addiction
3. Genetically modified mice provide information on treatments for cocaine dependence
4. Research shows cocaine reward picture more complicated than scientists thought
5. New study validates criteria for safe, rapid treatment of patients with cocaine-related chest pain
6. A new approach holds promise for reducing cocaine craving
7. Natures own antidote to cocaine
8. Estrogen may protect against cocaine-induced brain dysfunction
9. Scientists identify process that plays key role in brain changes involved in cocaine addiction
10. Brain contains cocaine-like chemical
11. Scientists identify brain chemicals involved in switching on cocaine addiction

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2020)... ... August 18, 2020 , ... Sentien Biotechnologies, Inc., a clinical-stage ... Food and Drug Administration (FDA) has approved the company’s Investigational New Drug (IND) ... severe COVID-19. Approval of this IND allows Sentien to initiate a Phase 1/2 ...
(Date:8/21/2020)... ... August 20, 2020 , ... ... Movahhed , a Clinical Operations executive with expertise in clinical trial planning and ... firm as an Expert Consultant. Throughout his career, Mr. Movahhed has helped design ...
(Date:8/7/2020)... ... August 06, 2020 , ... Alucio™, ... to announce that Eric Chen and Jessica Wong have joined the company’s leadership ... Strategy, respectively. , Eric Chen heads development efforts for Alucio’s flagship product, Beacon, ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... HOUSTON (PRWEB) , ... August ... ... a biopharmaceutical cold chain validation engineering firm, is making available for ... driving the need to incorporate concurrent transport simulation testing into today’s biologics ...
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International ... only $3950. With 50 million stem cells total, patients may choose which extremities they ... works for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue ...
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been touted as the solution ... history of eSource, the reasons it did not take off as quickly as people ... the industry is moving towards capturing data electronically for clinical trials and then repurposing ...
(Date:7/18/2020)... , ... July 16, 2020 , ... “We are thrilled ... Wave Bioactives. “It’s the only technology of its kind on the market and we ... onions with the protective capacity of traditional cultured ingredients, creating a natural way to ...
Breaking Biology Technology:
Cached News: