Rensselaer awarded $2.7 million NIH grant to improve drug development process

TROY, N.Y. -- The National Institutes of Health (NIH) has awarded Rensselaer Polytechnic Institute a $2.7 million, four-year grant to develop new tools for drug discovery. The grant, awarded in partnership with the University of California, Berkeley, Massachusetts Institute of Technology (MIT), and Oak Ridge National Laboratory, will support basic research intended to produce effective pharmaceuticals faster and more economically.

Jonathan Dordick, the Howard P. Isermann '42 Professor of Chemical and Biological Engineering at Rensselaer, leads the research team that includes Shekhar Garde, assistant professor of chemical and biological engineering at Rensselaer; Alexander Klibanov, professor of chemistry and bioengineering at MIT; Douglas Clark and Jeffrey Reimer, professors of chemical engineering at U.C. Berkeley; and Brian Davison, director of life sciences at Oak Ridge.

"This is a stellar partnership that relies on many different skill sets to complete the research," Dordick said. "Our goal is to develop a key set of tools to synthesize and screen promising compounds rapidly, and identify those most suitable for further development as potential new drugs." The current process of developing a single new therapeutic drug can take many years and cost up to $1.7 billion, according to a recent report in Chemical & Engineering News.

Recent advances in chemistry and screening techniques make it possible to identify large numbers of promising compounds, known as derivative libraries. Yet the subsequent testing required to evaluate each compound is expensive and slow. The resulting bottleneck in drug development has attracted considerable attention among researchers seeking to advance more efficient and affordable processes.

Dordick and the team are proposing a novel set of techniques that will, if successful, remove this bottleneck. "With this research," Dordick said, "we will be able to generate completely new compounds, accessing a w

Contact: Robert Pini
Rensselaer Polytechnic Institute

Page: 1 2

Related biology news :

1. Rensselaer marks the opening of the center for biotechnology and interdisciplinary studies
2. Rensselaer receives NIH grant to develop virtual surgery simulator
3. New software developed at Rensselaer predicts promising ingredients for new drugs
4. National Institutes of Health grant to Rensselaer to further research on healing bone injuries
5. Kimberly-Clark Worldwide donates intellectual property to Rensselaer
6. Rensselaer effort to pull mussels at Lake George looks promising
7. NASA Funds New Origin Of Life Center at Rensselaer Polytechnic Institute
8. Ecology of infectious diseases grants awarded
9. Joslin President awarded medal from international diabetes organization
10. UNC researchers awarded $8.65 million from National Institute on Aging
11. ESA awarded new SEEDS grant

Post Your Comments:

(Date:3/18/2019)... ... 18, 2019 , ... Early engagement not only improves and ... improves participation by better balancing scientific objectives with patient goals. , Reaching out ... entire process from development to market. Involving these groups in this manner ensures ...
(Date:3/14/2019)... ... ... Highmark Health’s VITAL Innovation Platform has been named the winner in the “Corporate Innovation” ... top honors in the awards. Winners were announced at an event on March 12 ... May 10 that also raises funds for Carnegie Science Center programs that inspire young ...
(Date:3/12/2019)... ... March 12, 2019 , ... FEITIAN Technologies ... all-in-one smart cards, announced today the launch of two new payment card types ... Dynamic CVV Payment cards. These advanced technologies will help all elements of the ...
Breaking Biology News(10 mins):
(Date:3/12/2019)... LIÈGE, Belgium (PRWEB) , ... March 12, 2019 ... ... for sample preparation and epigenetics research, has launched its third generation long-fragment DNA ... the second generation instrument with a user-friendly interface, automated processing, and the ...
(Date:3/5/2019)... ... 2019 , ... San Fransisko, or Sisko for short, is a German warmblood ... to pursue a career in dressage. According to Deborah, dressage came easy to ... ever worked with. Unfortunately, Sisko suffered an injury while playing in his pasture. ...
(Date:2/26/2019)... ... 2019 , ... The idea for Visikol began originally at ... tissue clearing technology for improved tissue characterization. From this initial idea, Visikol emerged ... primarily a services focused company. , Today, Visikol operates as a contract ...
(Date:2/16/2019)... TORONTO (PRWEB) , ... February 14, 2019 , ... ... data visualization, analytics, and knowledge sharing capability that also provides the flexibility for ... and play” functionality. It also provides a shared workbench to conduct quick analytics ...
Breaking Biology Technology:
Cached News: