HOME >> BIOLOGY >> NEWS
Report on dietary supplements containing ephedra makes urgent call for research to develop dose guidelines, safety warnings

A study undertaken for the Food and Drug Administration to assess the safety of popular dietary supplements containing ephedra concludes that these products can pose severe health risks and even kill some people, prompting an urgent need to pinpoint those at greatest risk and establish safe daily doses for the supplements. Scientists at the University of California, San Francisco who conducted the study also say ephedra-containing products should be more uniformly and explicitly labeled.

The analysis will appear in the December 21 issue of The New England Journal of Medicine. It has been posted early on the journal's web site due to its health implications.

The paper draws on a study the UCSF team prepared for the FDA, assessing 140 reports the agency received on adverse effects from ephedrine-containing supplements. The full report was published in the Federal Register earlier this year.

Of the 140 reports the FDA received concerning adverse effects analyzed, the researchers found that just under a third (31 percent), or 43 of the people "definitely" or "probably" suffered an adverse effect from ephedrine in a dietary supplement. Of these 43, three died, seven suffered permanent injury and four more required on-going medical treatment, the report shows.

Serious effects among these people included five cardiac arrests - two fatal and three resulting in permanent brain damage and disability; four strokes and ten cases of hypertension.

When a second group was included in the analysis - those whose physical symptoms were "possibly" related to ephedrine products - the number of deaths rose to ten out of 87 people, and permanent disabilities rose to 13 out of the 87.

The researchers call for large-scale, controlled studies to quantify the dangers of ephedrine-containing products and to identify who is vulnerable to the serious side effects -- steps needed to determine a maximum daily safe dose.

The UCSF scientists also urge the FDA to move q
'"/>

Contact: Wallace Ravven
wravven@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
6-Nov-2000


Page: 1 2 3 4

Related biology news :

1. Report outlines vision and recommendations for microbiology in the 21st Century
2. Report outlines steps needed to lessen smallpox threat
3. Reporters from Science Magazine to receive ASM Public Communications Award
4. Report in BioScience details global decline of nonmarine mollusks
5. National Academies news: Report on EPAs particulate matter research
6. Report details growing climate change threat to coral reefs
7. Report to aid nation in managing freshwaters
8. Report examines use of antibiotics in agriculture
9. Report offers action plan for curbing diseases that kill millions
10. Report focuses on the science and safety of genetically modified crops
11. Report considers role of science in a world made vulnerable by terrorism

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... LOS ANGELES , March 30, 2017  On ... Hack the Genome hackathon at ... This exciting two-day competition will focus on developing health ... experience. Hack the Genome is ... has been tremendous. The world,s largest companies in the ...
(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/23/2017)... report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), Product ... by MarketsandMarkets, the market is expected to be worth USD 18.98 billion by ... Continue Reading ... ...      (Logo: http://photos.prnewswire.com/prnh/20160303/792302) ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... ... 2017 , ... The award-winning American Farmer television series will feature 3 Bar ... Tuesdays at 8:30aET on RFD-TV. , With global population estimates nearing ten billion ... continue to feed a growing nation. At the same time, many of our valuable ...
(Date:10/9/2017)... Phoenix, Arizona (PRWEB) , ... October 09, 2017 ... ... of Kindred, a four-tiered line of medical marijuana products targeting the needs of ... production and packaging of Kindred takes place in Phoenix, Arizona. , As operators ...
(Date:10/7/2017)... , ... October 06, 2017 ... ... experience providing advanced instruments and applications consulting for microscopy and surface analysis, ... in application consulting, Nanoscience Analytical offers a broad range of contract analysis ...
(Date:10/7/2017)... WALTHAM, Mass. , Oct. 6, 2017 /PRNewswire/ ... pioneering work of three scientists, Jacques Dubochet, ... whose breakthrough developments in cryo-electron microscopy ... this technology within the structural biology community. The ... Scientific. Scientists can now routinely produce highly resolved, ...
Breaking Biology Technology:
Cached News: