HOME >> BIOLOGY >> NEWS
Research: Breast Cancer Gene Screening Not Warranted For All

By DAVID WILLIAMSON
UNC-CH News Services

CHAPEL HILL -- Screening for mutations in a gene known as BRCA1 that is believed to predispose women to breast cancer should not be done routinely because the mutations are less prevalent than researchers thought, according to a new study.

Widespread screening of breast cancer patients or unaffected women in the absence of family history would waste considerable money and is more likely to yield results that are hard to interpret, say scientists at the universities of North Carolina at Chapel Hill and Washington at Seattle. Testing may be helpful for women from families in which both breast and ovarian cancer have occurred or in which at least four cases of breast cancer have been identified.

"Women who inherit an altered form of this gene from either parent are at increased risk of breast cancer sometime during their lives," said Dr. Beth Newman, assistant professor of epidemiology at the UNC-CH School of Public Health. "Most previous comparable research took place among patients attending specialized cancer clinics so it was estimated that between 11 percent and 20 percent of women carried a defective gene. We found the frequency of breast cancer due to BRCA1 to be considerably lower than that."

For the first time, Newman and colleagues studied women with breast cancer who were not selected on the basis of their age at diagnosis or their family medical history to develop a better estimate of how common mutations in the gene were. Included were 211 N.C. breast cancer patients, ages 20 to 74, and 188 women without the illness who served as controls. About half the subjects were white, and about half were black.

A report on the findings appears in Wednesday's (March 25) issue of the Journal of the American Medical Association.


'"/>

Contact: David Williamson
rdtokids@email.unc.edu
919-962-8596
University of North Carolina at Chapel Hill
24-Mar-1998


Page: 1 2 3

Related biology news :

1. Research: Coral reefs decline actually began centuries ago
2. Research: U.S. boys also reaching puberty earlier than in past years
3. New Research: Children Inhale Higher Percentage Of Pollution
4. Progress In Prion Research: Three-Dimensional Structure Of Prion Protein Fully Uncovered
5. Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
6. Breastfeeding decreases infant mortality
7. Breast cancer study suggests role for tissue in carcinogenesis
8. Breast self examination increases womens concerns but has no effect on mortality
9. Breast cancer follow-ups no longer guess-work thanks to new physics research
10. Final media advisory for the 4th European Breast Cancer Conference (EBCC-4)
11. The 4th European Breast Cancer Conference (EBCC4)

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/1/2020)... ... ... More than 600 people undergo genetic counseling and testing each year as ... two genetic counselors. , My Gene Counsel , a digital health company that ... Rick Program to ensure that UConn’s patients who have undergone genetic testing for cancer ...
(Date:4/30/2020)... ... April 29, 2020 , ... ... continued growth – delivering innovative solutions for a wide range of industries including ... government agencies. A month into the new decade, it was clear to company ...
(Date:4/26/2020)... ... 23, 2020 , ... A team of researchers at the Icahn School of ... SARS-CoV-2, the virus that causes coronavirus disease (COVID-19). This antibody is intended to block ... for COVID-19. , The efforts are being led by Mone Zaidi, MD, PhD, MACP, ...
Breaking Biology News(10 mins):
(Date:5/30/2020)... ... May 29, 2020 , ... The Conference Forum ... newsletter solely dedicated to the unique role of the Chief Medical Officer in ... the responsibilities, problem-solving, best practices and career development of CMOs and Heads of ...
(Date:5/28/2020)... Md. (PRWEB) , ... May 28, 2020 , ... The ... biometrics and security leaders as the 2020 winners of the Women in Biometrics ... with sponsors IDEMIA , Biometric Update and the SIA Women ...
(Date:5/21/2020)... (PRWEB) , ... May 21, 2020 , ... ... of clinical trials will cause long-term harm , Contrary to conventional wisdom that ... Institute study finds many companies will emerge from the pandemic commercially weaker, ...
(Date:5/21/2020)... ... May 19, 2020 , ... Eaton Square is pleased to announce ... and Company, a biotechnology and medical technology-focused strategy and M&A advisory firm. , This ... United States, linking US and Asia Pacific healthcare innovators with capital and investors. , ...
Breaking Biology Technology:
Cached News: