HOME >> BIOLOGY >> NEWS
Research funded to develop plant-based diabetes treatment

BLACKSBURG, Va., July 9, 2001 Virginia Tech biochemistry and biology researchers are exploring whether plants can be engineered to produce a human enzyme to treat Type 2 diabetes. The research is being funded by a grant from Virginias Commonwealth Health Research Board (CHRB).

If Glenda Gillaspy's research leads in the direction she expects, plants will cheaply produce the human enzyme that is now painstakingly and expensively synthesized to treat 16 million Americans suffering from Type 2 diabetes, The CHRB has provided funding to Gillaspy, assistant professor of biochemistry, and collaborator Cynthia Gibas, assistant professor of biology, to lay the groundwork for what is expected to be the creation of a transgenic plant that will produce D-chiro inositol.

Gillaspys previous work included manipulation of inositol synthesis genes in plants to increase production of D-Chiro inositol precursors. She will be using information from the Arabidopsis plant, whose genome was totally decoded last year.

"This is the very beginning of a long process," Gillaspy said. "Were looking into how plants and animals synthesize this compound. Once we figure that out, we can look into how to make plants produce it in large quantities." Tobacco is likely to be the plant Gillaspy will try to manipulate to produce the compound because its genes are relatively easy to work with and it produces large amounts of material from which the compound can be extracted. The lack of D-chiro inositol causes Type 2 diabetes. The disease can be treated by replacing the missing inositol through medication.

"We are looking to eventually generate this compound in large quantities," Gillaspy said. "We hope the compound produced by plants will have the same properties as that produced in humans. At a deeper level, however, we are seeking to understand why the synthesis of this compound changes the signaling at the molecular level."


'"/>

Contact: Stewart MacInnis
macinnis@vt.edu
540-231-5863
Virginia Tech
9-Jul-2001


Page: 1

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Schepens Eye Research Institute receives Roadmap grant to develop center for curing eye diseases
4. Researchers identify protein promoting vascular tumor growth
5. Researchers devise potent new tools to curb ivory poaching
6. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
7. Researchers ID chlorophyll-regulating gene
8. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
9. Research suggests new avenue for stopping, preventing colon cancer
10. Researchers develop fast track way to discover how cells are regulated
11. Research on carbohydrate metabolism receives historical recognition

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/6/2019)... ... June 05, 2019 , ... MedTech Breakthrough , an ... and medical technology market, announced that it has selected Medacta International’s MySpine® MC ... in the 2019 MedTech Breakthrough Awards program. , Medacta® is ...
(Date:6/6/2019)... ... , ... Ziegler, a specialty investment bank, is pleased to ... on its recent acquisition by PathGroup. , Headquartered in Lewisville (Dallas), Texas, ... one dozen hospitals and surgery centers in the Dallas-Fort Worth and broader Texas ...
(Date:6/4/2019)... ... June 04, 2019 , ... Molecular Devices, a global leader ... the new President of Molecular Devices, replacing Greg Milosevich who has been appointed ... , Since joining Molecular Devices in a scientific engineering role, Ms. Murphy has ...
Breaking Biology News(10 mins):
(Date:5/14/2019)... JOLLA, Calif. (PRWEB) , ... May 14, 2019 , ... ... an office expansion, effectively doubling its space from 2,500 to 5,000 square feet. ... SneakPeek Early Gender DNA tests ,” says Gateway Genomics CEO, Chris Jacob. “The SneakPeek ...
(Date:5/4/2019)... ... May 03, 2019 , ... More than three thousand ... Association, the scientist and ufologist Urandir Fernandes de Oliveira, last Thursday (25), during ... results of some research carried out by the association, in partnership with scientists ...
(Date:5/2/2019)... CITY, S.D. (PRWEB) , ... April 30, 2019 , ... ... society, from industrial scale macro breweries to local craft breweries, and even home brewing ... involves very complex chemical and biological processes, that when mastered can produce a superb ...
(Date:5/2/2019)... ... May 02, 2019 , ... Boston Robotic Hair ... area. Gone are the days of painful hair transplant procedures. Boston Robotic Hair ... is the only robotic intelligent solution to offer a minimally invasive procedure. With ...
Breaking Biology Technology:
Cached News: