HOME >> BIOLOGY >> NEWS
Research suggests new way to repair cartilage damage

DURHAM, N.C. -- Duke biomedical engineers have developed a technique to use a natural polymer to fill in and protect cartilage wounds within joints, and to provide supportive scaffolding for new cartilage growth. Their advance offers a potential solution for a central problem in generating new cartilage: providing a support for cartilage cells as they regenerate cartilage tissue.

In tests on rabbits, Lori Setton, associate professor of biomedical engineering at Duke's Pratt School of Engineering, and her research team stimulated new cartilage growth in knee joint cartilage defects using a light-activated polymer hydrogel composed from a specialized molecule, hyaluronan. The hyaluronan-based polymer creates a protective cap over the wound, enabling joint movement while providing the structural support and chemical environment for new cartilage tissue to grow and fill the defect.

Dana Nettles, a graduate student in Setton's laboratory, presented the research findings on Monday, March 8, 2004, at the Orthopedic Research Society Annual meeting in San Francisco. A paper titled "In Situ Crosslinkable Hyaluronan for Articular Cartilage Repair" will be published in the March 2004 issue of Annals of Biomedical Engineering.

"We feel that the outcomes from this study suggest that therapies like this one hold promise for future, successful cartilage repair procedures," said Nettles.

Trauma and injuries to the knees and hips commonly involve damage to the articular cartilage, the thin layer lining the ends of articulating joints. If left untreated, the cartilage defects do not repair because the local cells are unable to regenerate new tissue. Patients suffering from cartilage damage will go on to develop osteoarthritis, a degenerative joint disease characterized by the breakdown of the joint's cartilage, causing pain and loss of movement. Nearly 21 million Americans suffer from osteoarthritis, principally in joints of the hip and knee.


'"/>

Contact: Deborah Hill
dahill@duke.edu
919-401-0299
Duke University
8-Mar-2004


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Schepens Eye Research Institute receives Roadmap grant to develop center for curing eye diseases
4. Researchers identify protein promoting vascular tumor growth
5. Researchers devise potent new tools to curb ivory poaching
6. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
7. Researchers ID chlorophyll-regulating gene
8. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
9. Research suggests new avenue for stopping, preventing colon cancer
10. Researchers develop fast track way to discover how cells are regulated
11. Research on carbohydrate metabolism receives historical recognition

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... NEW YORK , March 30, 2017 ... by type (physiological and behavioral), by technology (fingerprint, AFIS, ... recognition, voice recognition, and others), by end use industry ... travel and immigration, financial and banking, and others), and ... Europe , Asia Pacific ...
(Date:3/24/2017)... 2017 The Controller General of Immigration from Maldives ... Algeen have received the prestigious international IAIR Award for the most ... Reading ... Maldives ... Abdulla Algeen (small picture on the right) have received the IAIR award ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... The Blavatnik ... Winners and six Finalists of the 2017 Blavatnik Regional Awards for Young Scientists. ... Foundation and administered by the New York Academy of Sciences to honor the ...
(Date:10/12/2017)... CA (PRWEB) , ... October ... ... (https://www.onramp.bio/ ) has launched Rosalind™, the first-ever genomics analysis platform specifically designed ... bioinformatics complexity. Named in honor of pioneering researcher Rosalind Franklin, who made ...
(Date:10/11/2017)... Md. (PRWEB) , ... October 11, 2017 , ... ... digital pathology, announced today it will be hosting a Webinar titled, “Pathology is ... Advanced Pathology Associates , on digital pathology adoption best practices and how Proscia ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh ... orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of ... SBT-100 is able to cross the cell membrane and bind intracellular STAT3 and ...
Breaking Biology Technology:
Cached News: