Research suggests possible marker, preventive treatment for preeclampsia

WINSTON-SALEM, N.C. - New research findings suggest a possible marker - and preventive treatment - for preeclampsia, the second leading cause of pre-term birth in the United States.

Researchers from Wake Forest University Baptist Medical Center (WFUBMC) in Winston-Salem, N.C., and the Pontificia University in Santiago, Chile, said levels of angiotensin-(1-7), a naturally occurring hormone that helps "brake" high blood pressure, increase during normal pregnancies and are low in pregnant women with preeclampsia. The findings were reported at a meeting of the American Heart Association's Council for High Blood Pressure Research.

"While the cause of preeclampsia is currently unknown, this research indicates a possible mechanism for the condition," said David Merrill, M.D., a specialist in obstetrics and maternal/fetal medicine at WFUBMC. "Additional research is needed to show if low levels of angiotensin-(1-7) early in a pregnancy can predict preeclampsia, and if levels can be altered to prevent the disorder."

Preeclampsia, which affects about 5 percent of pregnancies, is characterized by high blood pressure, fluid retention and protein in the urine. In severe cases, untreated preeclampsia can lead to fetal or maternal death. Currently, the only treatment for preeclampsia is pre-term delivery.

K. Bridget Brosnihan, Ph.D., hypertension researcher at WFUBMC, said these were the first studies of the role of angiotensin-(1-7) in pregnancy. The hormone, identified earlier by WFUBMC researchers, causes blood vessels to dilate and is believed to be the body's natural "braking system" against high blood pressure.

In one study, conducted by Brosnihan, Merrill and Michael Karoly, M.D., all of WFUMBC, researchers measured levels of angiotensin-(1-7) in blood samples from three groups of women. The hormone's levels increased by 50 percent in normal pregnancies compared to a non-pregnant control group. In pregnant women with preeclampsia, levels o

Contact: Karen Richardson
Wake Forest University Baptist Medical Center

Page: 1 2

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Schepens Eye Research Institute receives Roadmap grant to develop center for curing eye diseases
4. Researchers identify protein promoting vascular tumor growth
5. Researchers devise potent new tools to curb ivory poaching
6. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
7. Researchers ID chlorophyll-regulating gene
8. Environmental issues center of Inland Northwest Research Alliance 4th Annual Symposium
9. Research suggests new avenue for stopping, preventing colon cancer
10. Researchers develop fast track way to discover how cells are regulated
11. Research on carbohydrate metabolism receives historical recognition

Post Your Comments:

(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
(Date:4/17/2017)... 17, 2017 NXT-ID, Inc. (NASDAQ: NXTD ... filing of its 2016 Annual Report on Form 10-K on Thursday ... ... available in the Investor Relations section of the Company,s website at ... website at http://www.sec.gov . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... (PRWEB) , ... October 12, ... ... ) has launched Rosalind™, the first-ever genomics analysis platform specifically designed for ... complexity. Named in honor of pioneering researcher Rosalind Franklin, who made a ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... pathology, announced today it will be hosting a Webinar titled, “Pathology is going ... Pathology Associates , on digital pathology adoption best practices and how Proscia improves ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... Administration (FDA) has granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal ... the treatment of osteosarcoma. SBT-100 is able to cross the cell membrane and ...
(Date:10/10/2017)... , Oct. 10, 2017 International research firm Parks Associates ... will speak at the TMA 2017 Annual Meeting , October 11 ... in the residential home security market and how smart safety and security ... Parks Associates: ... "The residential security ...
Breaking Biology Technology:
Cached News: