The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Researcher Awarded Patent For System To Fight Multiple Diseases

led in 1984 that the invention was not far enough advanced to be patentable.

However, in 1984, when it became possible to introduce genes from one pathogen into attenuated strains of another pathogen, Curtiss began to introduce streptococcal genes into attenuated types of Salmonella typhimurium. This led to his filing a Continuation-In-Part application on Sept. 9, 1985, which ultimately served as the basis for the patent issued this year.

According to Curtiss, securing the patent required that he demonstrate to the patent examiner a number of different advantages in using Salmonella: the ability to express a diversity of antigen genes from various bacteria, viruses, parasites and fungi in Salmonella; and the importance of the secretory immunoglobin (IgA) response. The IgA response occurs in such secretions as breast milk, tears and saliva and other areas where bacteria and viruses can enter the body. Curtiss's system invokes IgA immunity as a first line of defense against infection. At the time of patent application filing, there was almost no information about mucosal immunity in standard textbooks on immunology.

The technology currently is being used to develop recombinant vaccines to prevent or therapeutically treat infections due to Heliobacter pylori, which causes ulcers, Campylobacter jejuni, which causes diarrhea in poultry and humans, Mycobacterium tuberculosis, hepatitis B virus and a number of other pathogens for agricultural animals.

The patent has been licensed to MEGAN Health, Inc., a biotechnology company in St. Louis that is commercializing much of the technology that has arisen from research in Curtiss' laboratory over the past 20 years. Curtiss has a financial interest in MEGAN Health.

Two vaccines using Curtiss approaches to attenuate bacteria have been approved by the United States Department of Agriculture and are being marketed for use in preventing Salmonella infections in poult
'"/>

Contact: Tony Fitzpatrick
314-935-5272
Washington University in St. Louis
13-Apr-1999


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researcher Awarded Patent For System Fight Multiple Diseases

(Date:11/20/2008)...le in German . , Halle/Saale. For the firs...verview of which alien species are present in Euro...ment and society. More than 11,000 alien species h...vasive Species Inventory for Europe), a unique thr...an scientists, funded by the European Union that p...
(Date:11/20/2008)...g it. It is relentless and terminal. Auguries and ... and science fiction writers, researchers and plas...in the pursuits of "turning back the clock." Yet, ...to our name, at most. , Technological wizardry ... span still elude us? , If you ask Arizona Stat...
(Date:11/19/2008)...al Academy of Sciences (NAS) announced today the c...," an initiative designed to connect entertainment...gineers to help the creators of television shows, ...ate science into their work. The Exchange represe... to the entertainment community and provide the cr...
(Date:11/19/2008)...since the ancient thinker Archimedes shouted "Eure...pill out, scientist though the ages have solved ma...low. Today, the field of fluid dynamics addresses ...ronomy, engineering, alternative energy, and medic...ing of the year devoted to the dynamics of fluids ...
Breaking Biology News(10 mins):11,000 alien species invade Europe 2Fountain of Youth to be found in the anthill? 2Fountain of Youth to be found in the anthill? 3Fountain of Youth to be found in the anthill? 4NAS announces initiative to connect entertainment industry with top experts 2NAS announces initiative to connect entertainment industry with top experts 3Jupiter's shrinking red spot 2Jupiter's shrinking red spot 3Jupiter's shrinking red spot 4Jupiter's shrinking red spot 5Jupiter's shrinking red spot 6Jupiter's shrinking red spot 7Jupiter's shrinking red spot 8Jupiter's shrinking red spot 9Jupiter's shrinking red spot 10Anesiva and Sigma Tau Announce Exclusive Marketing and Distribution Agreement for Zingo 28TM 29 in Six European Countries 11562 1Anesiva and Sigma Tau Announce Exclusive Marketing and Distribution Agreement for Zingo 28TM 29 in Six European Countries 11562 2Anesiva and Sigma Tau Announce Exclusive Marketing and Distribution Agreement for Zingo 28TM 29 in Six European Countries 11562 3Mesa Labs Reports Higher Quarterly Sales and Earnings 11559 1Mesa Labs Reports Higher Quarterly Sales and Earnings 11559 2Mesa Labs Reports Higher Quarterly Sales and Earnings 11559 3Mesa Labs Reports Higher Quarterly Sales and Earnings 11559 4Mesa Labs Reports Higher Quarterly Sales and Earnings 11559 5Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 1Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 2Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 3Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 4Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 5Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 6Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 7Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 8Anesiva Announces Fourth Quarter and Year End 2007 Financial Results and Provides 2008 Outlook 3192 9Most With High Blood Pressure Dont Follow Recommended Diet 11558 1Most With High Blood Pressure Dont Follow Recommended Diet 11558 2
Other News:
...onal Institutes of Health announcing recently that... the Mount Desert Island Biological Laboratory is ...le project.......The decision to fund the sequenci...itted by MDIBL, the Genome Sequencing Center of Wa...
Bethesda, MD When the bacterium Listeria monocytogenes invades the body, it commandeers its host cell's actin cytoskeleton to invade other cells. In a report published in the Journal of Biological Ch
DALLAS March 21, 2005 Two UT Southwestern Medical Center scientists, Dr. Zhijian "James" Chen and Dr. Michael Rosen, whose research programs span the forefront of chemistry and biology, were named H
...e (HHMI) today announced the selection of 43 of th... new HHMI investigators. Two of these scientists, ...Cold Spring Harbor Laboratory on Long Island (pho...to providing these scientists--and the nearly 300 ...
NIH skate choice follows MDI Bio Lab white paper 2Scientists discover that host cell lipids facilitate bacterial movement 2Two UT Southwestern researchers named Howard Hughes Medical Institute investigators 2Two UT Southwestern researchers named Howard Hughes Medical Institute investigators 3HHMI taps two Long Island researchers as among the nation's most promising scientists 2
... ophthalmologists are encouraged by promising new ...l to reduce the devastating effects of wet AMD for...radigm of care, according to presentations made at...f Ophthalmology in New Orleans. ......Many experts...
...ified a protein in the brain that halts the progre.... The protein, known as "transthyretin," protects ... another toxic protein that contributes to the dis...onmental Health Sciences, a component of the Natio...
...Georgia professor, research means the most fundame...fe and death.......Three years ago Jeffrey K. Spri...dvertising and public relations of the Grady Colle... successful surgery for prostate cancer after a ro...
...of tea could help improve your memory, new researc...team from the University of Newcastle upon Tyne fo...of certain enzymes in the brain which are associat...ished in the academic journal, Phytotherapy Resear...
health news:Growing epidemic of wet AMD ushers in new era in treatment of the disease 2health news:Growing epidemic of wet AMD ushers in new era in treatment of the disease 3health news:Growing epidemic of wet AMD ushers in new era in treatment of the disease 4health news:Researchers identify brain protein that halts progression of Alzheimer's 2health news:Researchers identify brain protein that halts progression of Alzheimer's 3health news:UGA professor receives $3 million grant from National Cancer Institute for breast cancer research 2health news:Tea could improve memory, study shows 2health news:Tea could improve memory, study shows 3
A drug used to treat lymphoma, rheumatoid arthritis and other immune disorders may enable newly-diagnosed type 1 diabetics to save some of their pancreas function and thereby reduce their susceptibili
...ecent years, maple syrup has been made with revers...his week, the University of Vermont's Proctor Mapl...ned a new research building to test exactly what e... and flavor of syrup.......It is the only such res...
...ple living with HIV/AIDS and other diseases in Eth...Initiative and Yale University have joined forces ...e Ethiopian Hospital Management Initiative (EHMI) ...m in Ethiopia.......EHMI began at the request of D...
...en)(ASX:ACU), and Hawaii Biotech, Inc. (Hawaii Bio...hat they have entered into a Definitive Agreement ...e combined business, as yet unnamed, will be 50% o... and Avantogen Limited and will focus exclusively ...
health news:Study to test drug's potential to preserve insulin production in newly diagnosed type 1 diabetics 2health news:Study to test drug's potential to preserve insulin production in newly diagnosed type 1 diabetics 3health news:Tasting maple syrup, for science 2health news:Clinton Foundation, Yale and Ethiopian Ministry of Health forge partnership 2health news:Clinton Foundation, Yale and Ethiopian Ministry of Health forge partnership 3health news:Avantogen and Hawaii Biotech to combine vaccine businesses 2