HOME >> BIOLOGY >> NEWS
Researcher is using nature's command and control network to develop ways to engineer organisms

BLACKSBURG, Va. July 10, 2002 -- Peter Kennelly, a professor of biochemistry at Virginia Tech, is probing nature's own command and control network to understand how it functions and to develop new strategies for genetically engineering organisms. By mapping the mechanisms already in place to find the switch that controls a certain action, Kennelly is working to find ways to turn on processes that normally would not be active.

"Living organisms do an amazing amount of chemistry," says Kennelly. "The goals of life sciences are not only to take advantage of that machinery, but to control it so it can do more sophisticated tasks," he says. "Currently when we want a desirable trait in an organism, we introduce a gene that we put under artificial control to make a large quantity of the protein product of that gene."

The protein forces the organism to perform the desired task, but this is an inefficient and stressful method because it requires cells to produce hundreds of times more protein than is needed. "We tend to stress the organism because it has to use most of its resources to do the task," he says.

In contrast, turning on a specific switch already in place within the organism is more efficient and economical because the response is more proportionate. The maintenance of a more balanced distribution of resources among cellular processes also makes the organism more viable and robust. One application of the new method is in the development of biosensors, enzymes that are intermediaries in the natural sensing of outside events.

"If we did this from scratch, it would take us a long time, but we're able to do it more quickly if we take advantage of nature's existing engineering and modify it," Kennelly says.

He likens the way he works to the process used to develop airplanes, in which inventors looked at birds for the basic components and then modified those parts to work in something man made.

Events taking place within
'"/>

Contact: Peter Kennelly
pjkennel@vt.edu
540-231-4317
Virginia Tech
10-Jul-2002


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/14/2018)... ... December 14, 2018 , ... uBiome, ... “Method and System for Microbiome-Derived Diagnostics and Therapeutics” by the US Patent and ... 2014. The patent is an invention by uBiome collaborators Dr. Zachary Apte, Dr. ...
(Date:12/13/2018)... Fla. (PRWEB) , ... December 12, 2018 , ... New ... preventing the growing problem of drowsy and distracted driving, one of the main causes ... under the guidance of Dr. Kanwal Gagneja , assistant professor of computer science, ...
(Date:12/5/2018)... ... December 05, 2018 , ... Surgical Theater brings ... TN, from December 6-9, 2018 at booth #312. AANS/CNS provides Pediatric Neurosurgeons an ... the treatment continuum – from the consultation, to surgical planning, and into the ...
Breaking Biology News(10 mins):
(Date:1/10/2019)... ... ... Rascal was adopted from a local shelter when he was around two years old. ... six weeks after he was adopted, he tore his right cruciate ligament. Though he ... after such a traumatic injury. , Sure enough, when Rascal was about nine years old, ...
(Date:1/7/2019)... ... January 07, 2019 , ... Kainos ... its Parkinson's Disease drug candidate, code-named "KM-819." KM-819 is an orally active ... took place in South Korea. , This Phase 1 randomized, double-blind, placebo-controlled ...
(Date:12/20/2018)... (PRWEB) , ... December 20, 2018 , ... New Year’s ... with major changes in regulations in the European Union (EU) on the horizon, Jim ... to consider. , “The transition to the EU Medical Device Regulation (MDR), digital health, ...
(Date:12/18/2018)... (PRWEB) , ... December 18, 2018 , ... Patients with ... lumpectomy have better quality of life post-treatment versus whole breast irradiation, a new study ... are typically treated with whole breast irradiation after removal of the cancerous tumor because ...
Breaking Biology Technology:
Cached News: