HOME >> BIOLOGY >> NEWS
Researcher is using nature's command and control network to develop ways to engineer organisms

BLACKSBURG, Va. July 10, 2002 -- Peter Kennelly, a professor of biochemistry at Virginia Tech, is probing nature's own command and control network to understand how it functions and to develop new strategies for genetically engineering organisms. By mapping the mechanisms already in place to find the switch that controls a certain action, Kennelly is working to find ways to turn on processes that normally would not be active.

"Living organisms do an amazing amount of chemistry," says Kennelly. "The goals of life sciences are not only to take advantage of that machinery, but to control it so it can do more sophisticated tasks," he says. "Currently when we want a desirable trait in an organism, we introduce a gene that we put under artificial control to make a large quantity of the protein product of that gene."

The protein forces the organism to perform the desired task, but this is an inefficient and stressful method because it requires cells to produce hundreds of times more protein than is needed. "We tend to stress the organism because it has to use most of its resources to do the task," he says.

In contrast, turning on a specific switch already in place within the organism is more efficient and economical because the response is more proportionate. The maintenance of a more balanced distribution of resources among cellular processes also makes the organism more viable and robust. One application of the new method is in the development of biosensors, enzymes that are intermediaries in the natural sensing of outside events.

"If we did this from scratch, it would take us a long time, but we're able to do it more quickly if we take advantage of nature's existing engineering and modify it," Kennelly says.

He likens the way he works to the process used to develop airplanes, in which inventors looked at birds for the basic components and then modified those parts to work in something man made.

Events taking place within
'"/>

Contact: Peter Kennelly
pjkennel@vt.edu
540-231-4317
Virginia Tech
10-Jul-2002


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2018)... ... August 13, 2018 , ... NRD, LLC – NRD® is ... Ionizing Gun. , The ionizing gun features ergonomic design and rugged construction. ... filter and electropolished OSHA-compliant tip. This can be cleanroom packaged (P-2021-5502) or normally ...
(Date:8/14/2018)... ... August 14, 2018 , ... From ... movie “Wonder,” to a better understanding of congenital heart defects, 3-D printing is ... the latest special issue of Birth Defects Research (DOI: 10.1002/bdr2.1367). ...
(Date:8/7/2018)... ... 06, 2018 , ... Nurse practitioners and ... their healthcare careers in the past year, according to the second annual survey ... jobseekers with a wide variety of career- and employment-related resources including physician/candidate database, ...
Breaking Biology News(10 mins):
(Date:7/24/2018)... ... ... R3 Stem Cell is now offering regenerative therapies for COPD lung disease ... Certified providers, with outcomes significantly improving patient quality of life. , Traditional therapies for ... help repair and regenerate damaged lung tissues. Stem cell therapy for COPD ...
(Date:7/24/2018)... ... 24, 2018 , ... On August 6, 2018, BioMedGPS will ... Not just a pretty face, SmartTRAK 3.0’s latest improvements were inspired by its ... world’s first online and real-time data portal that specializes in providing competitive market ...
(Date:7/22/2018)... ... July 19, 2018 , ... Mitotech ... with Essex Bio-Investment for Phase 3 clinical program in Dry Eye Disease. Under ... SkQ1 with approximately $17m allocated towards the first Phase 3 study starting as ...
(Date:7/22/2018)... ... July 20, 2018 , ... ... automation and IT solutions with 150 employees on both the east and west ... Program. Superior Controls met the high criteria for application expertise, operational excellence ...
Breaking Biology Technology:
Cached News: