HOME >> BIOLOGY >> NEWS
Researcher traces gene development in 'last common link'

A researcher studying the last common link between invertebrate and vertebrate animals has found a key genetic change that separates the spineless from the backboned.

Jeremy Gibson-Brown, Ph.D., assistant professor of biology at Washington University in St. Louis, studies amphioxus, a small marine worm, a primitive invertebrate species that is the closest living invertebrate related to vertebrates like ourselves. Gibson-Brown has found that a gene involved in the development of a body layer in invertebrates duplicated within the vertebrate lineage after the development of amphioxus.

However, in vertebrates, this gene, AmphiEomes/Tbr1, gave rise to two genes, Eomesodermin and T-brain-1, involved in brain development. While the vertebrate Eomesodermin gene has retained its original function in forming the mesoderm, or "middle skin" layer,in all vertebrate studies from fish, to amphibians to humans, the duplicate copy has lost that function and instead has evolved a role in forebrain development.

"This shows us how old genes can give birth to new ones, and how the origins of novel developmental functions can be traced," said Gibson-Brown, who will have his results published in a forthcoming issue of the Journal of Experimental Zoology. His next step will be to look for these genes in lampreys, primitive jawless fish similar to the ancestors of later vertebrates.

"I want to see whether this gene duplication predated the separation of jawless fish and vertebrates and whether the role in forebrain development had yet been acquired."

Fruit flies, mice, worms and apes share an amazing amount of genetic information with us humans and with each other. For instance, there is only one-tenth of one percent genetic variation between a human and a chimpanzee.

A field of research has arisen to address what kinds of genetic change over time have occurred in different species to account for so many physical differences despite such gene
'"/>

Contact: Tony Fitzpatrick
tony_fitzpatrick@aismail.wustl.edu
314-935-5272
Washington University in St. Louis
16-Apr-2002


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researcher traces gene development last common link

(Date:7/29/2014)... world of science, researchers sometimes need to get ... did just that to study the impacts of ... coral reef ecosystems at two remote locations in ... animal tracking and computer simulation, McCauley, an assistant ... Marine Biology, and his colleagues sought to understand ...
(Date:7/29/2014)... journey to the edge of science, Clment Vidal takes ... Beginning and the End: Does our universe have a ... we alone in the universe? What is the role ... in science and committed to philosophical rigor, the book ... life is not an accident, but may well be ...
(Date:7/29/2014)... 29, 2014  When it comes to technology, healthcare is usually ... the last. However, when it comes to wearables, healthcare is trying ... for the Internet of Things and its wearable cousins is less ... the healthcare industry, whether it,s in the hospital for a major ... With that in mind, InformationWeek editor Rodney Brown ...
Breaking Biology News(10 mins):Underwater elephants 2Underwater elephants 3Book: 'The Beginning and the End' 2
(Date:7/30/2014)... 30, 2014 NCERC at Southern ... present his findings on corn stover pretreatment methods ... week in Washington, D.C. , “Arun’s selection ... is a testament to the success of our ... “Thanks to the foresight and vision of SIUE ...
(Date:7/30/2014)... LayerBio, Inc., an MIT spinoff developing ... round of seed financing from friends and family investors. ... develop a novel sustained-release product for ophthalmology. , "We ... their commitment to this important work," said Dr. Ken ... of many areas in which innovations in drug delivery ...
(Date:7/29/2014)...   Sequenom, Inc. (NASDAQ: SQNM ... analysis solutions, and Mayo Medical Laboratories (MML), ... the United States , have announced a ... "We have great appreciation for Mayo Clinic,s ... welcome the opportunity to partner with the organization,s leading ...
(Date:7/29/2014)... ELLICOTT CITY, Md. , July 29, 2014 ... has announced a new and updated program for ... October 10 – 12, 2014 in Amelia ... sponsors, CROs, sites and investigators remains unchanged, however, ... more purposeful exchange and networking opportunity among all ...
Breaking Biology Technology:NCERC at SIUE Researcher Takes Stage at Department of Energy Conference 2NCERC at SIUE Researcher Takes Stage at Department of Energy Conference 3Sequenom Enters Into License Agreement With Mayo Medical Laboratories 2Sequenom Enters Into License Agreement With Mayo Medical Laboratories 3Sequenom Enters Into License Agreement With Mayo Medical Laboratories 4TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 2TransCelerate, Lilly, Pfizer, and FDA Highlight Collaborative Program at the Site Solutions Summit 3
Cached News: