HOME >> BIOLOGY >> NEWS
Researcher traces gene development in 'last common link'

A researcher studying the last common link between invertebrate and vertebrate animals has found a key genetic change that separates the spineless from the backboned.

Jeremy Gibson-Brown, Ph.D., assistant professor of biology at Washington University in St. Louis, studies amphioxus, a small marine worm, a primitive invertebrate species that is the closest living invertebrate related to vertebrates like ourselves. Gibson-Brown has found that a gene involved in the development of a body layer in invertebrates duplicated within the vertebrate lineage after the development of amphioxus.

However, in vertebrates, this gene, AmphiEomes/Tbr1, gave rise to two genes, Eomesodermin and T-brain-1, involved in brain development. While the vertebrate Eomesodermin gene has retained its original function in forming the mesoderm, or "middle skin" layer,in all vertebrate studies from fish, to amphibians to humans, the duplicate copy has lost that function and instead has evolved a role in forebrain development.

"This shows us how old genes can give birth to new ones, and how the origins of novel developmental functions can be traced," said Gibson-Brown, who will have his results published in a forthcoming issue of the Journal of Experimental Zoology. His next step will be to look for these genes in lampreys, primitive jawless fish similar to the ancestors of later vertebrates.

"I want to see whether this gene duplication predated the separation of jawless fish and vertebrates and whether the role in forebrain development had yet been acquired."

Fruit flies, mice, worms and apes share an amazing amount of genetic information with us humans and with each other. For instance, there is only one-tenth of one percent genetic variation between a human and a chimpanzee.

A field of research has arisen to address what kinds of genetic change over time have occurred in different species to account for so many physical differences despite such gene
'"/>

Contact: Tony Fitzpatrick
tony_fitzpatrick@aismail.wustl.edu
314-935-5272
Washington University in St. Louis
16-Apr-2002


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researcher traces gene development last common link

(Date:2/5/2015)... Carolina , 5. Februar 2015 /PRNewswire/ ... als spezialisiertes Logistikunternehmen und hat eine neue ... klinische Logistikfirma (Clinical Logistics Organization – CLO) ... neuen Kampagne lautet First , mit ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... , January 28, 2015 ... Analysis, Size And Segment Forecasts To 2020 has Been ... IR camera market is expected to reach USD 5.10 ... Grand View Research, Inc. IR cameras help identify the ... are expected to witness surging demand in medical imaging ...
(Date:1/22/2015)... 22, 2015 Research and Markets ( http://www.researchandmarkets.com/research/4trb7t/biometrics_a ) ... Global Market Overview" report to their offering. , ... ensure that an individual is who she/he is claiming to ... of a person,s unique physical characteristics, such as fingerprint, hand ...
Breaking Biology News(10 mins):Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 3Biometrics - A Global Market Overview 2Biometrics - A Global Market Overview 3
(Date:3/4/2015)... Lancée par l,Assistance ... en décembre 2011, l,étude collaborative française randomisée ... compare   l es microsphères en résine ... le carcinome hépatocellulaire avancé, a recruté plus de ...   ; les résultats sont attendus fin 2016. ...
(Date:3/3/2015)... and TORONTO, March 3, 2015 /PRNewswire/ - Aptose Biosciences ... new therapeutics and molecular diagnostics that target the underlying ... quarter and seventh-month period ended December 31, 2014. ... fiscal year end from May 31 to December 31. ... are reporting today are for the quarter and the ...
(Date:3/3/2015)... WASHINGTON , March 3, 2015 NASA astronaut ... his launch this month to spend a year living and ... live satellite interviews from 5:30 to 7 a.m. EDT Monday, ... Moscow as he completes the final weeks of ... by a video on NASA Television highlighting his mission training ...
(Date:3/3/2015)... ON , March 3, 2015 /PRNewswire/ - BIOREM Inc. (TSXV: ... $3.7 million.  The orders are for odour control projects in ... and Asia . "Bidding activity ... , President and CEO. "After a high volume year for bidding ... into the New Year.  The recent orders reflect the organization,s renewed ...
Breaking Biology Technology:Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 2Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 3Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 4Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 5Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 2Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 3Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 4Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 5Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 7Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 8Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 9Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 10Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 11Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 12NASA Astronaut Scott Kelly Available for Interviews before One-Year Space Station Mission 2
Cached News: