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Researchers Find Protein Abnormality Associated With Alzheimer's Disease

at Rhode Island Hospital and the lab of Justin Fallon, associate professor of neuroscience. Other authors include David Glass and George Yancopoulos, scientists at Regeneron Pharmaceuticals in Tarrytown, NY.

In previous research, Fallon showed that agrin contributes to development of the connection between nerve and muscle cells. Agrin causes "clustering" of neurotransmitter receptors on the muscle cell, to ensure proper communication with the nervous system.

All experiments in the study being reported this month were performed on post-mortem brain tissue donated to the Brown University Brain Bank. The study was supported by grants from the National Institutes of Health.


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Contact: Scott Turner
Scott_Turner@Brown.edu
401-863-1862
Brown University
25-May-1999


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