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Researchers Make Breakthrough In Gene Transfer

use, in a matter of days, people will be able to make cell populations that express a gene of interest," Rice says. "The transfected cells are normal and capable of division. This is a tremendous advantage in studies where you don't want the vector to perturb the biology of the cell."

Agapov EV, Frolov I, Lindenbach B, Pragai BM, Schlesinger S, Rice CM (1998). Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. Proceedings of the National Academy of Sciences, 95.

Grants from the Public Health Service supported this research.


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Contact: Linda Sage
sage@medicine.WUSTL.edu
314-286-0119
Washington University School of Medicine
27-Oct-1998


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