HOME >> BIOLOGY >> NEWS
Researchers concerned over early egg retrieval after cancer treatment - doctors advised to monitor pregnancies as mice study reveals problems

An international team of fertility experts is asking doctors to monitor carefully the pregnancies and babies of all women who undergo egg retrieval and IVF after cancer chemotherapy.

Research on mice has shown that cylophosphamide - a commonly used drug belonging to a group of anti-cancer agents known as alkylating agents - causes fetal malformations and pregnancy failure. More importantly, the new study reveals that the effect on the embryo is influenced by the stage of egg follicle development at the time of exposure to the drug.

Although the researchers stress that there is no evidence as yet to suggest equivalent treatment-induced problems in human eggs, they believe that their findings indicate that eggs collected from women within six to 12 months of treatment could be particularly vulnerable to damage.

The study has been carried out by Dr Dror Meirow at the Rabin Medical Centre and Schneider Children Medical Centre in Israel, Drs Michal Epstein and Hadassa Lewis at the Hadassah Medical Centre in Jerusalem, Dr David Nugent at the University of Leeds in the UK, and Professor Roger Gosden at the Royal Victoria Hospital, Montreal, Canada.

The results are reported today* (Thursday 29 March) in Europe's leading fertility journal, Human Reproduction.

Although research has already shown that cyclophosphamide can induce genetic damage and has raised concerns about pregnancies in cancer survivors and the health of the children, all the studies on pregnancy outcome to date have been reassuring, suggesting that these concerns are unfounded. However, the research was on women who became pregnant a long time after treatment stopped.

New reproductive techniques mean that many centres offer egg retrieval and embryo freezing before starting cancer treatment that is likely to result in infertility. But delaying life-saving treatment while patients undergo egg-retrieval cycles may be inadvisable. So some centres now offer IVF and embryo cryopreser
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
44-0-1536 772181
European Society for Human Reproduction and Embryology
28-Mar-2001


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/4/2017)... VEGAS , Jan. 4, 2017  For the thousands of attendees ... a global leader in connected health and biometric measurement devices and services, ... monitors. On display in A&D Medical,s special CES Exhibit ... represent the ongoing expansion of the company,s WellnessConnected product platform.  ... ...
(Date:12/20/2016)... , Dec. 20, 2016 The ... sharing, rental and leasing is stoking significant interest ... radio frequency technology, Bluetooth low energy (BLE), biometrics ... as the next wave of wireless technologies in ... access system to advanced access systems opens the ...
(Date:12/16/2016)... The global wearable medical device market, in terms of value, is ... billion in 2016, at a CAGR of 18.0% during the forecast ... Growth ... devices, launch of a growing number of smartphone-based healthcare apps compatible ... and increasing focus on physical fitness. Furthermore, growing ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) today ... earnings conference call will be broadcast live over the ... Eastern Time.  A news release detailing the quarterly and ... Eastern Time the morning of the conference call. ... Zimmer Biomet,s Investor Relations website at http://investor.zimmerbiomet.com . ...
(Date:1/17/2017)... NEW YORK , Jan. 17, 2017 /PRNewswire/ ... mobile health coaching, is the first to offer ... and obesity. Noom,s Spanish diabetes prevention ... expand the reach and accessibility of lifestyle interventions ... of developing these conditions. Noom,s robust food database, ...
(Date:1/17/2017)... , Jan. 17, 2017  Only nine percent ... patients over profits, while only 16 percent believe health ... released today. Meanwhile, 36 percent of U.S. adults believe ... patients over profits, compared to hospitals (23%). ... maelstrom," said Wendy Salomon , vice president of ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... 2016 annual meeting of the North American Spine Society (NASS)1 demonstrate high ... the majority of cases, when PEEK-OPTIMA™ HA Enhanced is used for interbody-fusion ...
Breaking Biology Technology:
Cached News: