HOME >> BIOLOGY >> NEWS
Researchers concerned over early egg retrieval after cancer treatment - doctors advised to monitor pregnancies as mice study reveals problems

An international team of fertility experts is asking doctors to monitor carefully the pregnancies and babies of all women who undergo egg retrieval and IVF after cancer chemotherapy.

Research on mice has shown that cylophosphamide - a commonly used drug belonging to a group of anti-cancer agents known as alkylating agents - causes fetal malformations and pregnancy failure. More importantly, the new study reveals that the effect on the embryo is influenced by the stage of egg follicle development at the time of exposure to the drug.

Although the researchers stress that there is no evidence as yet to suggest equivalent treatment-induced problems in human eggs, they believe that their findings indicate that eggs collected from women within six to 12 months of treatment could be particularly vulnerable to damage.

The study has been carried out by Dr Dror Meirow at the Rabin Medical Centre and Schneider Children Medical Centre in Israel, Drs Michal Epstein and Hadassa Lewis at the Hadassah Medical Centre in Jerusalem, Dr David Nugent at the University of Leeds in the UK, and Professor Roger Gosden at the Royal Victoria Hospital, Montreal, Canada.

The results are reported today* (Thursday 29 March) in Europe's leading fertility journal, Human Reproduction.

Although research has already shown that cyclophosphamide can induce genetic damage and has raised concerns about pregnancies in cancer survivors and the health of the children, all the studies on pregnancy outcome to date have been reassuring, suggesting that these concerns are unfounded. However, the research was on women who became pregnant a long time after treatment stopped.

New reproductive techniques mean that many centres offer egg retrieval and embryo freezing before starting cancer treatment that is likely to result in infertility. But delaying life-saving treatment while patients undergo egg-retrieval cycles may be inadvisable. So some centres now offer IVF and embryo cryopreser
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
44-0-1536 772181
European Society for Human Reproduction and Embryology
28-Mar-2001


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/12/2018)... PARK, Calif. (PRWEB) , ... September 10, 2018 ... ... that a paper detailing the performance of its new Multiplexed Ion Beam Imaging ... the September 6 issue. This study will also be shared during a webinar ...
(Date:9/12/2018)... Fla. (PRWEB) , ... September 12, 2018 , ... ... and intuitive spine fusion solutions announced today it has received 510(k) clearance from ... Pedicle Screw complementing its TowerLOX® MIS Pedicle Screw System. , TowerLOX-EXT MIS Extended ...
(Date:9/7/2018)... ... September 06, 2018 , ... CTL Medical Corporation has entered ... spine business, which includes its complete portfolio of spine-related patents and 510ks, as ... it. The deal will make CTL Medical the world’s exclusive provider of silicon ...
Breaking Biology News(10 mins):
(Date:8/23/2018)... ... August 22, 2018 , ... Crucial Data Solutions, Inc. ... it the first fully-featured app for electronic data capture (EDC) and electronic participant ... constitute 99 percent of the market share for mobile devices worldwide; in turn, ...
(Date:8/17/2018)... ... August 16, 2018 , ... The opening of the new Titusville facility ... Services in 2016. Chemko had a well established local presence, servicing the Space Coast ... projects such as the ongoing work at the Mobile Launch Platform (MLP) in support ...
(Date:8/14/2018)... , ... August 13, 2018 , ... ... chemical fume hoods and biological safety cabinets. In addition, Labconco produces other lab ... one measure of its commitment to quality and consistency in design and manufacturing. ...
(Date:8/9/2018)... ... August 08, 2018 , ... ... platform by combining its deep pharmaceutical compliance and technical expertise with professional ... periodic pharmaceutical GxP training requirements. , Bringing training to life for ...
Breaking Biology Technology:
Cached News: