HOME >> BIOLOGY >> NEWS
Researchers develop first mouse model of epithelial ovarian cancer

in the United States.

Early detection of these tumors is challenging because there is no standard screening available for the disease. When ovarian cancer is diagnosed at early stages, the survival rate approaches 90 percent. However, the vast majority of cases of ovarian cancer are not identified until late stages, when the survival rate drops to only 30 to 40 percent.

"The development of mouse models of epithelial ovarian cancer may significantly facilitate advances in early detection and treatment of the disease," said Thomas C. Hamilton, Ph.D., senior member of the medical science division at Fox Chase Cancer Center and leader of the ovarian cancer research program. "Models such as this are critical to cancer research because they will allow us to study the progression of ovarian cancer from the very earliest stages to advanced disease.

"The next step is to test chemotherapeutic and chemopreventive agents that we hope will translate into meaningful improvements in the prevention and treatment of ovarian cancer. We'll also study the relevant oncogenes and tumor-suppressor genes for their ability to allow or trigger the cancer to develop," Hamilton added.

Other contributing researchers include Rudi Bao, M.D., Kasie C. Stephens, Timothy W. Poole, Ph.D., Xiang Hua and Skye S. Harris of Fox Chase Cancer Center; Alexander Yu. Nikitin, M.D., Ph.D., of Cornell University; and Barbara C. Vanderhyden, Ph.D., of the University of Ottawa.

Funding for this research is provided in part by a grant from the National Cancer Institute's Mouse Models of Human Cancers Consortium (MMHCC), of which Hamilton is a member. Mouse models that recapitulate many aspects of the genesis, progression and clinical course of human cancers are valuable resources to cancer researchers engaged in a variety of basic, translational, clinical and epidemiological investigations.

MMHCC is a collaborative program designed to derive and characteri
'"/>

Contact: Karen Mallet
k_carter@fccc.edu
215-728-2700
Fox Chase Cancer Center
15-Mar-2003


Page: 1 2 3

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: