Researchers find possible link between pre-natal alcohol consumption and diabetes

April 9, 2003 (San Diego) -- The name is misleading but diabetes insipidus is not associated with diabetes mellitus (which is also called sugar diabetes). Victims of this disorder have kidneys that fail to adequately concentrate urine very well, leading to increased frequency of urination. Diabetes insipidus patients are thirsty all the time, finding the need to consume liquids every hour. The causes of diabetes insipidus are unclear. In some, a part of the brain (called the hypothalamus) doesn't make enough antidiuretic hormone (called ADH, and also called by its chemical name, arginine-vasopressin or AVP); in others, the kidneys don't work with this hormone the way they should. Most people with diabetes insipidus are diagnosed following an injury to the head or after brain surgery. A brain tumor is sometimes present in those with this disease; about one in four have no discernible reason for diabetes insipidus.

A new study conducted under the auspices of the Departments of Defense and Army may have found that prenatal ethanol exposure in rats can lead to a partial central diabetes insipidus evident in the young adult. This is supported by the observations that pre-natal ethanol (PE)-exposed rats drank twice as much water, had reduced pituitary content of AVP, a 50 percent reduction in the genetic material in the hypothalamus necessary for the synthesis of AVP, a reduced response of AVP release to an osmotic stimulus, and increased basal plasma salt concentration (osmolality). [Note: Vasopressin regulates blood volume and salt concentration. Animals deprived of water detect increases in salt concentration in the hypothalamus, which causes the release of vasopressin, thereby increasing water retention. Feedback from the kidneys, through release of renin and activation of angiotensin, elevates blood pressure and leads to activation of cells in the lateral hypothalamus, which control drinking behavior.]

These findings may be significant for those

Contact: Donna Krupa
American Physiological Society

Page: 1 2 3 4

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:

(Date:11/19/2019)... ... November 19, 2019 , ... Project Lifeline – ... Stores (NACDS) Foundation to address substance use disorder (SUD) – will take ... who have led to the program’s effectiveness in preventing and treating opioid abuse in ...
(Date:11/19/2019)... ... 19, 2019 , ... The inaugural Cell & Gene Therapy Day takes place ... one-day event will be chaired by Dr Aiman Shalabi, VP R&D, Cell and Gene ... “We are witnessing significant innovation in cell and gene therapies, and we are at ...
(Date:11/14/2019)... ... 13, 2019 , ... NDA Partners Chairman Carl Peck, ... and program management executive with more than 33 years of regulatory and product ... as an Expert Consultant. , Robert Peterson has extensive experience in formulating ...
Breaking Biology News(10 mins):
(Date:12/18/2019)... ... December 17, 2019 , ... ... is pleased to announce that it has hired Dr. Alia Orbin, Ph.D., J.D., ... is experienced in the preparation, filing and prosecution of patent applications related to ...
(Date:12/6/2019)... Calif. (PRWEB) , ... December ... ... device manufacturer Vascular Medcure, Inc. has received FDA 510(k) clearance for its ... The company’s early clinical data suggests the CAPERE® offers great benefits for ...
(Date:12/4/2019)... , ... December 03, 2019 , ... Bold Brahim aka ... on his right front leg. After several weeks of medical management, his condition worsened ... of California Equine Orthopedics . Results revealed Jesse had a severe injury to ...
(Date:12/4/2019)... ... 2019 , ... The technology at the heart of Nanopareil revolves ... on the pharmaceutical industry could be massive. , “The pharmaceutical industry really needs this ... South Dakota School of Mines & Technology and one of the researchers to ...
Breaking Biology Technology:
Cached News: