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Researchers identify protein that kills cancer cells

he researchers believe it may help existing therapies work better.

"Most therapeutic tools we currently use for cancer act by triggering cells to self-destruct," Dieckgraefe says. "So it's entirely possible that this might become a synergistic addition to existing therapies. By augmenting existing chemotherapy with CUGBP2, we might be able to make traditional therapies more effective."

In addition, the team says COX-2 might not be the only protein that CUGBP2 influences. Anant and Dieckgraefe say broad ranges of proteins have similar targets, so they believe CUGBP2 may have a role in regulating the production of those proteins, too.


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Contact: Jim Dryden
drydenj@msnotes.wustl.edu
314-286-0110
Washington University School of Medicine
17-Jan-2003


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