Researchers seek siblings with Parkinson's disease for national genetic study

INDIANAPOLIS -- In one of the largest studies of its kind, researchers are seeking siblings diagnosed with Parkinson's disease to identify the genetic markers that may indicate a predisposition for developing this movement disorder.

Indiana University School of Medicine is the principal institution of the 49 centers in the United States, Puerto Rico and Canada participating in the five-year study known as PROGENI (Parkinson's Research: The Organized Genetic Initiative).

P. Michael Conneally, Ph.D., distinguished professor of medical and molecular genetics and of neurology at the IU School of Medicine, is the principal investigator for the $6 million study funded by the National Institute of Neurological Diseases and Stroke, part of the National Institutes of Health.

"This is an enormous undertaking; we are seeking 600 pairs of siblings who have Parkinson's disease," said Dr. Conneally. "Our goal is to understand the genetics of Parkinson's by isolating the genetic markers that contribute to a predisposition to the disease."

Information from the U.S. Human Genome Project will be used to help isolate the genetic markers for Parkinson's disease. Researchers believe greater understanding of the genes contributing to Parkinson's disease will likely lead to more effective treatments.

To be eligible for the study, two or more brothers and sisters with Parkinson's disease must both be available for clinical evaluation. Siblings do not need to live in the same city. Participants will be asked to complete a screening questionnaire, undergo a neurological examination and permit the drawing of blood to obtain DNA. The physical and neurological evaluation, as well as the blood draw, are administered at no cost to the participant and all information is strictly confidential.

To enroll in the project or to request additional information, please contact Cheryl Halter at the IU School of Medicine, toll free at 1-8

Contact: Mary Hardin
Indiana University

Page: 1 2

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:

(Date:7/10/2020)... ... July 08, 2020 , ... ... Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, 2020 • 1:30 p.m.-3:00 ... but what is the most effective way to complete one? Will the study ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. ... of Neihulizumab, a biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), ... Dr. Paul J Martin of the Fred Hutchinson Cancer Research Center, this single-arm, ...
(Date:7/1/2020)... ... July 01, 2020 , ... ... and solutions for glioblastoma—the most common and aggressive adult brain cancer—announced today the ... PhD. Senior Fellows are charged with supporting the organization’s initiatives and overall vision. ...
Breaking Biology News(10 mins):
(Date:8/3/2020)... ... August 03, 2020 , ... ERT, the global ... has been named one of the 100 most inspiring individuals in the life-sciences ... are selected based on how they have inspired their colleagues and affected positive ...
(Date:7/31/2020)... , ... July 29, 2020 , ... ... solid-state radar transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, ... that can drive one or two switches in a push-pull configuration; yielding fast ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... the top radiation centers in 16 countries, has reached its 20th anniversary of ... now in routine use at top universities including University of Pennsylvania, University of ...
(Date:7/18/2020)... ... ... “We are thrilled to deliver this new technology to the industry” said Matt Hundt, ... market and we were pleased that the IFT jury recognized that.” reFRESH™ couples the ... natural way to extend the shelf life and improve the safety of perishable foods ...
Breaking Biology Technology:
Cached News: