HOME >> BIOLOGY >> NEWS
Researchers to compare prenatal treatments for serious twin complication

-birth circulation.

Both treatments aim to obtain a more normal balance of amniotic fluid between the twins, although only the laser treatment addresses the underlying anatomical defect. However, the two treatments have not previously been directly compared in a clinical trial.

This study will evaluate which treatment, laser photocoagulation or amnioreduction, results in better survival rates and better cardiac, neurological and developmental outcomes. In addition to studying health outcomes immediately after birth, the researchers also will assess the twins neurodevelopment at age 18 to 22 months.

Twelve medical centers throughout the United States will participate in the TTTS trial, sponsored by the National Institutes of Health. While all 12 centers perform amnioreduction, only two, The Childrens Hospital of Philadelphia and the University of California, San Francisco, also perform fetoscopic laser coagulation. Those two institutions also are the only centers in the world offering comprehensive treatments in fetal surgery.

Enrollment for the multicenter TTTS study began in March 2002 and is scheduled to continue through March 2005. Throughout the country, researchers expect to recruit a total of 150 patients for the trial, of which approximately half will be recruited by The Children's Hospital of Philadelphia.

Because of the requirements of randomized studies, each mother who enrolls in the trial will be randomly assigned to either amnioreduction treatment or laser treatment. Participating centers will not perform the laser treatment outside of the clinical trial.


'"/>

Contact: John Ascenzi
Ascenzi@email.chop.edu
215-590-7332
Children's Hospital of Philadelphia
22-Apr-2002


Page: 1 2

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/9/2016)... 9, 2016 Elevay is currently ... expanding freedom for high net worth professionals seeking travel ... globally connected world, there is still no substitute for ... duplicate sealing your deal with a firm handshake. This ... taking advantage of citizenship via investment programs like those ...
(Date:4/28/2016)... -- First quarter 2016:   , Revenues ... first quarter of 2015 The gross margin was 49% ... and the operating margin was 40% (-13) Earnings per ... from operations was SEK 249.9 M (21.2) , Outlook ... 7,000-8,500 M. The operating margin for 2016 is estimated ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016   Boston Biomedical , an ... designed to target cancer stemness pathways, announced that ... Orphan Drug Designation from the U.S. Food and ... cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin is ... inhibit cancer stemness pathways by targeting STAT3, and ...
(Date:6/23/2016)... 2016  The Prostate Cancer Foundation (PCF) is pleased to announce ... cures for prostate cancer. Members of the Class of 2016 were selected from ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... In a ... Hospital in Denmark detail how a patient who developed lymphedema after being treated for ... The results could change the paradigm for dealing with this debilitating, frequent side effect ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... exhibiting at the Pennsylvania Convention Center and will showcase its product’s latest features ... will also be presenting a scientific poster on Disrupting Clinical Trials in The ...
Breaking Biology Technology:
Cached News: