HOME >> BIOLOGY >> NEWS
Researchers uncover surprising degree of large-scale variation in the human genome

nd susceptibility to health problems such as neurological disease, cancer, and obesity is an intriguing possibility. The study revealed considerable structural variation in the human genome, most of which was not previously apparent by other methods of genomic analysis.

Previous studies by others using different methods had identified only a handful of such large-scale copy number polymorphisms in human DNA. The increased CNP detection frequency in the new study stems from the greater resolving power of the ROMA technology (which currently employs one probe every 35 kb) relative to other methods. Moreover, several features of ROMA result in a signal-to-background ratio superior to that which can be obtained by hybridization of total genomic DNA to an array of BACs. Further refinements of ROMA, which promise to reveal more information about large-scale polymorphisms in the human genome, are underway.


'"/>

Contact: Peter Sherwood
sherwood@cshl.edu
516-367-6947
Cold Spring Harbor Laboratory
22-Jul-2004


Page: 1 2

Related biology news :

1. Researchers determine genetic cause of Timothy syndrome
2. Researchers find color sensitive atomic switch in bacteria
3. Researchers identify protein promoting vascular tumor growth
4. Researchers devise potent new tools to curb ivory poaching
5. Researchers create nanotubes that change colors, form nanocarpet and kill bacteria
6. Researchers ID chlorophyll-regulating gene
7. Researchers develop fast track way to discover how cells are regulated
8. Researchers identify distinctive signature for metastatic prostate cancer
9. Researchers report new gene test for isolated cleft lip and palate
10. Researchers discover why mutant gene causes colon cancer
11. Researchers identify the genomes controlling elements

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/23/2019)... ... , ... NanoFUSE is pleased to announce the ... spine and orthopedic use. Bioactive glass is a calcium phosphate coated silica that ... orthopedics for over 30 years and now NanoFUSE Biologics has used advanced research ...
(Date:7/19/2019)... ... July 19, 2019 , ... ... and Crystalline States – Insights from Synchrotron X-ray Pair Distribution (SXPDF) Studies”. The ... with Chris Benmore of Argonne National Laboratory and Gabriel de Araujo of the ...
(Date:7/17/2019)... Pa. (PRWEB) , ... July 15, 2019 , ... ... of computational science expertise exclusively for Life Sciences and Healthcare companies, announces the ... provide critical advisory services and strategic direction to start-up and emerging bio-pharma companies ...
Breaking Biology News(10 mins):
(Date:6/11/2019)... Fla. (PRWEB) , ... June 10, 2019 , ... ... in science and technology in an upcoming episode, scheduled to broadcast 4Q/2019. Check ... the Eppendorf Group) and will educate viewers about how its technology facilitates laboratories ...
(Date:6/11/2019)... POWAY, Calif. (PRWEB) , ... June 11, 2019 ... ... parent company of Personalized Stem Cells Inc. (PSC) , has announced that ... of Public Health, Food and Drug Branch for manufacturing. This is an ...
(Date:5/31/2019)... ... May 29, 2019 , ... For many years, the primary forms of cancer ... breakthrough therapies. Advances in immuno-oncology have led to the advent of Chimeric Antigen Receptor ... T cell receptors known as “CARs”. The CAR enables the final product to produce ...
(Date:5/31/2019)... ... May 30, 2019 , ... Object ... announce the strategic acquisition of Metabiologics, Inc., a globally recognized leader in the ... ownership and commercialization rights to a full spectrum of botulinum neurotoxins, as well ...
Breaking Biology Technology:
Cached News: