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Researchers unlock secrets of directional cell movement

hen became evenly distributed around the outside of the cell and that the cells became equally sensitive at all points.

"What this tells us is that a cell can sense all over its surface but it can only lead with its front end," says Devreotes. The researchers say that although others have suggested that an uneven distribution of proteins might be involved in chemotaxis, theirs is the first such protein to be concretely identified as doing so.

For more information on chemotaxis research, travel to the Devreotes Lab at http://www.med.jhu.edu/devreotes/ . Graphics are also available at this site.

Other authors of the study are Tian Jin, Ning Zhang, Yu Long, and Carole Parent. The National Institutes of Health funded the research.


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Contact: Kate O'Rourke
korourke@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
10-Feb-2000


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