The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Resistance exercise resets the body clock

Resistance exercise may directly reset the body clocks in skeletal muscle, according to research published in Genome Biology this week. This result may partly explain how exercising early in the day helps jet-lagged bodies readjust to their new time zone.

Many processes in the body vary in a 24-hour rhythm called the circadian rhythm. These rhythms are controlled by molecular clocks, in organs such as the liver, in tissues such as skeletal muscle, and in the hypothalamus, a part of the brain. The clock in the hypothalamus is the central controller and keeps all the peripheral clocks in synch.

Exercise can reset circadian rhythms. Most scientists thought this process was mediated purely by inputs to the hypothalamus, which can alter the expression of genes in the central clock. Now researchers, from the Gladstone Institute of Cardiovascular Disease, the University of California, and Northwestern University, have found that exercise can also alter the expression of clock genes in the muscles themselves.

The research team, headed by Bruce Conklin, analysed the expression of a wide range of genes in human skeletal muscle biopsies. These biopsies were taken from both legs of four male volunteers, 6 and 18 hours after they had exercised only their right leg for half an hour.

To find out if the expression of different genes in skeletal muscle varied over time, the researchers assessed which genes were 'switched on or off' at different times of the day in the unexercised legs. They discovered hundreds of genes that increased or decreased their expression over time. By studying previously published results from similar experiments in mice, they found 44 genes that are regulated in a circadian rhythm in one or more mouse tissues and human skeletal muscle. These included some genes involved in the molecular clock, namely Per1, Per2 and Clock.

The team then went on to see if the timing of the expression of these genes could be altered b
'"/>

Contact: Gemma Bradley
press@biomedcentral.com
44-207-323-0323
BioMed Central
24-Sep-2003


Page: 1 2

Related biology news :

1. Insect antibiotics Resistance is futile!
2. Resistance training complements aerobic exercise for women
3. K-State Researchers Study Pest Resistance Management
4. Maggots Could Help Address Problems Of Antibiotic Resistance
5. In The Genes: Extra Belly Fat, Insulin Resistance Linked
6. Researchers Report Emergence Of Antibiotic Resistance During Vancomycin Therapy
7. A "Fossil" Virus Involved In AIDS Drug Resistance?
8. Alcohol Consumption, Resistance To Its Effects Related To Levels Of Neurotransmitter, Say UW Researchers
9. Scientists Locate A Genetic On/Off Switch In Diphtheria; Find May Yield Antibiotics That Wont Boost Bacterial Resistance
10. Local Approaches To Combating Antibiotic Resistance Are Doomed To Failure
11. Structure Of Enzyme Involved In Gentamicin Resistance Revealed For First Time

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Resistance exercise resets the body clock

(Date:11/4/2009)..., Calif., Nov. 4 GenVault Corporat...ody, M.D., Ph.D., has joined its Board of Director... of the Salk Institute, is an acclaimed physician-... the Salk Institute, Dr. Brody served as president...of the National Academy of Engineering and the Ins...
(Date:11/3/2009)...ark may be the ultimate loner of the ocean, cruisi...am of researchers has discovered that the sharks h...ion that over tens of thousands of years the white...arated themselves into a population genetically di...ite sharks are a large, highly mobile species," sa...
(Date:11/3/2009)...EST LAFAYETTE, Ind. - Chief executives in 35 of th... 129 times their "ideal salaries" in 2008, accordi...by a Purdue University researcher to determine fai...economic and corporate governance issues of the da... said Venkat Venkatasubramanian, a professor of ch...
Breaking Biology News(10 mins):Dr. William Brody, President of the Salk Institute for Biological Studies, Appointed to GenVault's Board of Directors 2Dr. William Brody, President of the Salk Institute for Biological Studies, Appointed to GenVault's Board of Directors 3Tags reveal white sharks have neighborhoods in the north Pacific, say Stanford researchers 2Tags reveal white sharks have neighborhoods in the north Pacific, say Stanford researchers 3Tags reveal white sharks have neighborhoods in the north Pacific, say Stanford researchers 4New theory on fairness in economics targets CEO pay 2New theory on fairness in economics targets CEO pay 3New theory on fairness in economics targets CEO pay 4New Certification Commission for Healthcare Interpreters Opens Doors to Improve Provider Patient Communication 26 Quality Medical Care 57223 1New Certification Commission for Healthcare Interpreters Opens Doors to Improve Provider Patient Communication 26 Quality Medical Care 57223 2New Certification Commission for Healthcare Interpreters Opens Doors to Improve Provider Patient Communication 26 Quality Medical Care 57223 3Gene Switch May Help Drive Excess Fluid in Lungs 57218 1Comprehensive cardiac CT scan may give clearer picture of significant heart disease 57214 1Comprehensive cardiac CT scan may give clearer picture of significant heart disease 57214 2
(Date:11/6/2009)... Intarcia Therapeutics, Inc. delivered two present...us delivery of exenatide) program for the treatmen...Technology Meeting in San Francisco, CA: ,, (Lo...SFTU126LOGO ) ,, Continuous Subcutaneous Deli...se, HbA1c and Reduces Weight in a 28-day Phase 1b ...
(Date:11/5/2009)...irstCall/ -- GenVec, Inc. (Nasdaq: GNVC ) today a...er ended September 30, 2009. GenVec reported a net...ree months ended September 30, 2009 compared to a ...comparable quarter of 2008. For the nine months en...1 million ($0.15 per share), compared to a net los...
(Date:11/5/2009).../ -- Imagenetix, Inc. (OTC Bulletin Board: IAGX), ...d CEO of Imagenetix, will be presenting the Compan... Thursday, December 3rd, at 10:30 AM PST at the Lu..., LD MICRO is a by-invitation only newsletter fir... the micro-cap space. Since 2002, the firm has pub...
(Date:11/5/2009)...ll/ -- Transgenomic, Inc. (OTC Bulletin Board: TBI...er ended September 30, 2009. The Company,s financi.... ,, Third Quarter 2009 ,, The Company rep...r the third quarter of 2009 as compared to a net l...uarter of 2008. ,, Net sales were $5.0 million...
Breaking Biology Technology:Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 2Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 3Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 4Intarcia Therapeutics, Inc. Presents Positive Results from Two Studies of ITCA 650 for the Treatment of Type 2 Diabetes at the Ninth Annual Diabetes Technology Meeting 5GenVec Reports Third Quarter 2009 Financial Results 2GenVec Reports Third Quarter 2009 Financial Results 3GenVec Reports Third Quarter 2009 Financial Results 4GenVec Reports Third Quarter 2009 Financial Results 5GenVec Reports Third Quarter 2009 Financial Results 6Imagenetix to Present at 2nd Annual LD MICRO Conference at the Luxe Sunset Bel Air 2Transgenomic, Inc. Reports Third Quarter 2009 Results 2Transgenomic, Inc. Reports Third Quarter 2009 Results 3Transgenomic, Inc. Reports Third Quarter 2009 Results 4Transgenomic, Inc. Reports Third Quarter 2009 Results 5Transgenomic, Inc. Reports Third Quarter 2009 Results 6Transgenomic, Inc. Reports Third Quarter 2009 Results 7
Other News:
...id drawn from the crustal rocks that make up most ...dence yet to support the controversial assertion t...ding to H. Paul Johnson, a University of Washingto...t being published March 25 in the American Geophys...
...ter report that a group of rare urological defects......may be more common in children conceived throug...ution, however, that the findings are preliminary,...considering the procedure.......Information collec...
Two new faculty members have been selected as Clare Boothe Luce Assistant Professors in the Department of Civil and Environmental Engineering. Sarah L. Billington and Alexandria B. Boehm, who joined t
...cells make connections with one another by extendi...e growing tips of these nerve cell processes are g...lar cues in the environment. ......A Salk Institu... interaction that guides nerve cells along specifi...
15-foot hypodermic needles provide evidence for vast oceanic crustal biosphere 215-foot hypodermic needles provide evidence for vast oceanic crustal biosphere 315-foot hypodermic needles provide evidence for vast oceanic crustal biosphere 4In vitro fertilization may be linked to bladder defects 2Sarah Billington and Alexandria Boehm named Clare Boothe Luce Assistant Professors 2
...July 19, 2005, at the Society of Conservation Biol... Hole Research Center and the Instituto de Pesquis...ational symposium on the prospects for large-scale...asin. ......This region has entered a new era of ...
...OKEN, N.J. -- Stevens Institute of Technology, Sou...ent of Environmental Protection have announced a j...rk Harbor. The technology/education partnership wa...m South Street Seaport on June 22.... The Seaport ...
...diff (UK) scientists are playing a major role in a...ing matter in the icy layers beneath the surface o... make a historic encounter with Comet Tempel-1 on ...into the comet and tunnel through its outer layers...
...n Diego, June 29th) -- Investigators from the Univ...Ludwig Institute for Cancer Research (LICR) and Ni... to identify thousands of regulatory sequences in ...oday in Nature.......Genes are defined by their ab...
Historic schooner carries Stevens technology to monitor NY Harbor 2NASA probe could reveal comet life, scientists claim 2Whole genome promoter mapping - Human Genome Project v2.0? 2