HOME >> BIOLOGY >> NEWS
Rice finds 'on-off switch' for buckyball toxicity

HOUSTON, Sept. 24, 2004 -- Researchers at Rice University's Center for Biological and Environmental Nanotechnology (CBEN) have demonstrated a simple way to reduce the toxicity of water-soluble buckyballs by a factor of more than ten million.

The research will appear in an upcoming issue of the journal Nano Letters, published by the American Chemical Society, the world's largest scientific society. One of the first toxicological studies of buckyballs, the research was published online by the journal on Sept. 11.

Buckyballs, whose chemical notation is C60, are hollow, soccerball-shaped molecules containing 60 carbon atoms. Their diameter is just one-billionth of a meter, or one nanometer, and their discovery at Rice in 1985 is widely regarded as an early milestone in the field of nanotechnology.

While buckyballs show great promise in applications as diverse as fuel cells, batteries, pharmaceuticals and coatings, some scientists and activists have raised concerns about their potential toxicity to humans and animals.

CBEN's study is the first cytotoxicity study of human cells exposed to buckyballs. Cytotoxicity refers to toxic effects on individual cells. The study found that even minor alterations to the surface of the buckyballs can dramatically affect how toxic they are to individual cells, and the researchers identified specific alterations that render them much less toxic.

"There are many cases where toxicity is desirable," said Vicki Colvin, CBEN director, professor of chemistry and chemical engineering, and the principal investigator for the research. "For example, we might want particles that kill cancer cells or harmful bacteria. In other cases -- like applications where particles may make their way into the environment -- toxicity is undesirable."

In the study, the researchers exposed two types of human cells to various solutions containing different concentrations of buckyballs. Four types of solutions were test
'"/>

Contact: Jade Boyd
jadeboyd@rice.edu
713-348-6778
Rice University
24-Sep-2004


Page: 1 2 3

Related biology news :

1. Cigarette smoke causes breaks in DNA and defects to a cells chromosomes, Pitt study finds
2. DNA barcode finds four new bird species
3. Folic acid vitamin use by women reaches all-time high, March of Dimes survey finds
4. South Dakota Tech grad student finds rare whale
5. Purdue study finds antioxidant protects metal-eating plants
6. Medication reconciliation, pharmacist involvement vital to reducing medication errors, study finds
7. Scientist who discovered Sly syndrome finds new research path to explore for treating the disease
8. Study finds anti-HIV protein evolved millions of years before the emergence of AIDS
9. Drug prevents chemotherapy-induced hearing loss, study finds
10. Old is young, study finds
11. Study finds plant enzyme function changes with location in cell

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... VENICE, Calif. (PRWEB) , ... July 01, 2020 ... ... focused on building awareness and solutions for glioblastoma—the most common and aggressive adult ... and Lisa Haile, JD, PhD. Senior Fellows are charged with supporting the organization’s ...
(Date:6/28/2020)... , ... June 25, 2020 , ... In an upcoming ... innovations in accelerated Point of Care Testing solutions (POCT). Check local listings for more ... collected at medical offices and are shipped to labs throughout the country. Results are ...
(Date:6/23/2020)... (PRWEB) , ... June 23, ... ... provider of gene-to-protein and monoclonal antibody development services, today announced that the ... products and services to the pharmaceutical, diagnostics, and research industries. The decision ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... July 16, 2020 , ... Medial EarlySign , ... and prevention of high-burden diseases, and Centric Consulting, a business and technology consulting ... utilize existing data in order to identify and prioritize patients for care. , ...
(Date:7/10/2020)... ... July 09, 2020 , ... PathSensors Inc., ... has expanded the company’s exclusive license to include clinical applications for CANARY™ ... market, focusing initially on the SARS-CoV-2 biosensor. CANARY’s™ fast and highly ...
(Date:7/7/2020)... (PRWEB) , ... July 06, 2020 , ... R3 International ... program featuring up to 200 million stem cells. Depending on the patient's condition, treatment ... in the US will die having some form of Alzheimers dementia, and the incidence ...
(Date:7/1/2020)... Ohio (PRWEB) , ... June 29, 2020 , ... ... offers access to competitively procured purchasing contracts to its membership, recently named ... provide TIPS members with the opportunity to purchase ergonomic seating, cafeteria tables, book ...
Breaking Biology Technology:
Cached News: